Effects of Probiotic
AGS cell line
Saccharomyces boulardii
anticancer properties
postbiotic
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
27 Apr 2023
27 Apr 2023
Historique:
received:
27
03
2023
revised:
11
04
2023
accepted:
15
04
2023
medline:
15
5
2023
pubmed:
13
5
2023
entrez:
13
5
2023
Statut:
epublish
Résumé
Gastric cancer has been recognized as the second most probable cause of death in humans from cancer diseases around the world. Postbiotics, supernatant, and metabolites from probiotic microorganisms have recently been used widely to prevent and treat cancer diseases in humans, without any undesirable side effects. This study explores the antiproliferative and antitumor activities of the probiotic We evaluated cell growth inhibitory and mechanical properties of the cytoplasmic membrane and the downregulation of SBS significantly inhibits the AGS cell growth, and the concentrations with IC Considering the antitumor activities of SBS on AGS cell line, it can be regarded as a prospective therapeutic and preventive strategy against human stomach cancer disease.
Sections du résumé
BACKGROUND
BACKGROUND
Gastric cancer has been recognized as the second most probable cause of death in humans from cancer diseases around the world. Postbiotics, supernatant, and metabolites from probiotic microorganisms have recently been used widely to prevent and treat cancer diseases in humans, without any undesirable side effects. This study explores the antiproliferative and antitumor activities of the probiotic
METHODS
METHODS
We evaluated cell growth inhibitory and mechanical properties of the cytoplasmic membrane and the downregulation of
RESULTS
RESULTS
SBS significantly inhibits the AGS cell growth, and the concentrations with IC
CONCLUSIONS
CONCLUSIONS
Considering the antitumor activities of SBS on AGS cell line, it can be regarded as a prospective therapeutic and preventive strategy against human stomach cancer disease.
Identifiants
pubmed: 37175663
pii: ijms24097945
doi: 10.3390/ijms24097945
pmc: PMC10178855
pii:
doi:
Substances chimiques
Survivin
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Références
Rev Argent Microbiol. 2020 Jan - Mar;52(1):27-30
pubmed: 31262611
Cancer Med. 2019 Aug;8(10):4709-4721
pubmed: 31222971
Clin Ther. 2020 Sep;42(9):1637-1648
pubmed: 32800382
Gut Pathog. 2022 Apr 25;14(1):16
pubmed: 35468857
Pharmaceutics. 2022 Jul 29;14(8):
pubmed: 36015202
Lancet. 2020 Aug 29;396(10251):635-648
pubmed: 32861308
Trends Immunol. 2019 Apr;40(4):310-327
pubmed: 30890304
Mol Cell Biochem. 2008 Jun;313(1-2):125-32
pubmed: 18398671
Adv Nutr. 2019 Jan 1;10(suppl_1):S49-S66
pubmed: 30721959
Food Sci Nutr. 2020 Nov 29;9(2):692-700
pubmed: 33598154
Molecules. 2023 Jan 27;28(3):
pubmed: 36770898
J Fungi (Basel). 2020 Jun 04;6(2):
pubmed: 32512834
J Dairy Sci. 2013;96(12):7511-20
pubmed: 24140317
Int J Mol Sci. 2022 Apr 07;23(8):
pubmed: 35456891
Cancer Lett. 2013 May 28;332(2):225-8
pubmed: 22410464
J Immunol. 2003 Aug 1;171(3):1526-33
pubmed: 12874246
Cancer Metastasis Rev. 2020 Dec;39(4):1179-1203
pubmed: 32894370
Nutrients. 2023 Feb 28;15(5):
pubmed: 36904230
Asian Pac J Cancer Prev. 2011;12(7):1675-9
pubmed: 22126543
J Anim Sci Biotechnol. 2022 Apr 8;13(1):38
pubmed: 35392985
World J Gastroenterol. 2022 Mar 28;28(12):1187-1203
pubmed: 35431510
Probiotics Antimicrob Proteins. 2022 Dec 22;:
pubmed: 36547769
Probiotics Antimicrob Proteins. 2023 Jan 2;:
pubmed: 36588138
Nutr Cancer. 2018 Jan;70(1):83-96
pubmed: 29144773
Probiotics Antimicrob Proteins. 2022 Dec;14(6):1130-1138
pubmed: 35094296
Clin Gastroenterol Hepatol. 2020 Mar;18(3):534-542
pubmed: 31362118
Probiotics Antimicrob Proteins. 2022 Sep 1;:
pubmed: 36048406
CA Cancer J Clin. 2021 May;71(3):264-279
pubmed: 33592120
Nat Rev Gastroenterol Hepatol. 2023 May;20(5):271-287
pubmed: 36631716
Med Res Rev. 2019 May;39(3):887-909
pubmed: 30421440