Content aware image restoration improves spatiotemporal resolution in luminescence imaging.
Journal
Communications biology
ISSN: 2399-3642
Titre abrégé: Commun Biol
Pays: England
ID NLM: 101719179
Informations de publication
Date de publication:
13 05 2023
13 05 2023
Historique:
received:
24
05
2022
accepted:
28
04
2023
medline:
15
5
2023
pubmed:
14
5
2023
entrez:
13
5
2023
Statut:
epublish
Résumé
Luminescent reporters are due to their intrinsically high signal-to-noise ratio a powerful labelling tool for microscopy and macroscopic in vivo imaging in biomedical research. However, luminescence signal detection requires longer exposure times than fluorescence imaging and is consequently less suited for applications requiring high temporal resolution or throughput. Here we demonstrate that content aware image restoration can drastically reduce the exposure time requirements in luminescence imaging, thus overcoming one of the major limitations of the technique.
Identifiants
pubmed: 37179375
doi: 10.1038/s42003-023-04886-z
pii: 10.1038/s42003-023-04886-z
pmc: PMC10183019
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
518Informations de copyright
© 2023. The Author(s).
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