Health consequences of exposure to aircraft contaminated air and fume events: a narrative review and medical protocol for the investigation of exposed aircrew and passengers.

Humans Aircraft Air Pollution Air Pollution, Indoor Organophosphates Review Literature as Topic
Aerotoxic syndrome Aircrew Bleed air Cabin air Fume events Oil fumes Organophosphates

Journal

Environmental health : a global access science source
ISSN: 1476-069X
Titre abrégé: Environ Health
Pays: England
ID NLM: 101147645

Informations de publication

Date de publication:
16 05 2023
Historique:
received: 21 12 2022
accepted: 31 03 2023
medline: 18 5 2023
pubmed: 17 5 2023
entrez: 16 5 2023
Statut: epublish

Résumé

Thermally degraded engine oil and hydraulic fluid fumes contaminating aircraft cabin air conditioning systems have been well documented since the 1950s. Whilst organophosphates have been the main subject of interest, oil and hydraulic fumes in the air supply also contain ultrafine particles, numerous volatile organic hydrocarbons and thermally degraded products. We review the literature on the effects of fume events on aircrew health. Inhalation of these potentially toxic fumes is increasingly recognised to cause acute and long-term neurological, respiratory, cardiological and other symptoms. Cumulative exposure to regular small doses of toxic fumes is potentially damaging to health and may be exacerbated by a single higher-level exposure. Assessment is complex because of the limitations of considering the toxicity of individual substances in complex heated mixtures.There is a need for a systematic and consistent approach to diagnosis and treatment of persons who have been exposed to toxic fumes in aircraft cabins. The medical protocol presented in this paper has been written by internationally recognised experts and presents a consensus approach to the recognition, investigation and management of persons suffering from the toxic effects of inhaling thermally degraded engine oil and other fluids contaminating the air conditioning systems in aircraft, and includes actions and investigations for in-flight, immediately post-flight and late subsequent follow up.

Identifiants

DOI: 10.1186/s12940-023-00987-8 PMID: 37194087 PMC: PMC10186727
pubmed: 37194087
doi: 10.1186/s12940-023-00987-8
pii: 10.1186/s12940-023-00987-8
pmc: PMC10186727
doi:

Substances chimiques

Organophosphates 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

43

Subventions

Organisme : NIEHS NIH HHS
ID : P42 ES004696
Pays : United States

Commentaires et corrections

Type : ErratumIn

Informations de copyright

© 2023. The Author(s).

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Auteurs

Jonathan Burdon (J)

Respiratory Physician, St Vincent's Private Hospital, East Melbourne, Australia.

Lygia Therese Budnik (LT)

Institute for Occupational and Maritime Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Xaver Baur (X)

European Society for Environmental and Occupational Medicine, Berlin, Germany.
University of Hamburg, Hamburg, Germany.

Gerard Hageman (G)

Department of Neurology, Medisch Spectrum Twente, Hospital Enschede, Enschede, The Netherlands.

C Vyvyan Howard (CV)

Centre for Molecular Biosciences, University of Ulster, Coleraine, Northern Ireland, UK.

Jordi Roig (J)

Department of Pulmonary Medicine, Clínica Creu Blanca, Barcelona, Spain.

Leonie Coxon (L)

Clinical and Forensic Psychologist, Mount Pleasant Psychology, Perth, Australia.

Clement E Furlong (CE)

Departments of Medicine (Div. Medical Genetics) and Genome Sciences, University of Washington, Seattle, USA.

David Gee (D)

Centre for Pollution Research and Policy, Visiting Fellow, Brunel University, London, UK.

Tristan Loraine (T)

Technical Consultant, Spokesperson for the Global Cabin Air Quality Executive, London, UK.

Alvin V Terry (AV)

Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, USA.

John Midavaine (J)

Lifemedic Bilthoven, Bilthoven, The Netherlands.

Hannes Petersen (H)

Faculty of Medicine, University of Iceland, Akureyri Hospital, Akureyri, Iceland.

Denis Bron (D)

Federal Department of Defence, Civil Protection and Sport (DDPS), Aeromedical Institute (FAI)/AeMC, Air Force, Dübendorf, Switzerland.

Colin L Soskolne (CL)

School of Public Health, University of Alberta, Edmonton, AB, Canada.

Susan Michaelis (S)

Occupational and Environmental Health Research Group, Honorary Senior Research Fellow, University of Stirling, Scotland / Michaelis Aviation Consulting, West Sussex, England. susan@susanmichaelis.com.

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Classifications MeSH

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questionsmedicales.fr › Technologie, industrie et agriculture › Transports › Aviation › Véhicules de transport aérien › Health consequences of exposure to aircraft...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pollution de l'environnement › Pollution de l'air › Health consequences of exposure to aircraft...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pollution de l'environnement › Pollution de l'air › Pollution de l'air intérieur › Health consequences of exposure to aircraft...
questionsmedicales.fr › Composés chimiques organiques › Composés organiques du phosphore › Organophosphates › Health consequences of exposure to aircraft...
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