Prematurity and Hyperoxia Have Different Effects on Alveolar and Microvascular Lung Development in the Rabbit.


Journal

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
ISSN: 1551-5044
Titre abrégé: J Histochem Cytochem
Pays: United States
ID NLM: 9815334

Informations de publication

Date de publication:
05 2023
Historique:
medline: 29 5 2023
pubmed: 18 5 2023
entrez: 18 5 2023
Statut: ppublish

Résumé

Bronchopulmonary dysplasia (BPD) is a developmental disorder of infants born prematurely, characterized by disrupted alveolarization and microvascular maturation. However, the sequence of alveolar and vascular alterations is currently not fully understood. Therefore, we used a rabbit model to evaluate alveolar and vascular development under preterm birth and hyperoxia, respectively. Pups were born by cesarean section 3 days before term and exposed for 7 days to hyperoxia (95% O

Identifiants

pubmed: 37199233
doi: 10.1369/00221554231177757
pmc: PMC10227883
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

259-271

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Auteurs

Giacomo Rößler (G)

Institute of Functional and Applied Anatomy, Hannover Medical School, Hannover, Germany.
Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.

Jonas Labode (J)

Institute of Functional and Applied Anatomy, Hannover Medical School, Hannover, Germany.
Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.

Yannick Regin (Y)

Department of Development and Regeneration, KU Leuven, Leuven, Belgium.

Thomas Salaets (T)

Department of Development and Regeneration, KU Leuven, Leuven, Belgium.
Department of Paediatrics, UZ Leuven, Leuven, Belgium.

André Gie (A)

Department of Development and Regeneration, KU Leuven, Leuven, Belgium.
Department of Paediatrics and Child Health, Faculty of Medicine, Stellenbosch University, Cape Town, South Africa.

Jaan Toelen (J)

Department of Development and Regeneration, KU Leuven, Leuven, Belgium.
Department of Paediatrics, UZ Leuven, Leuven, Belgium.

Christian Mühlfeld (C)

Institute of Functional and Applied Anatomy, Hannover Medical School, Hannover, Germany.
Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.
Research Core Unit Electron Microscopy, Hannover Medical School, Hannover, Germany.

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Classifications MeSH