A Synthetic Cumate-Inducible Promoter for Graded and Homogenous Gene Expression in Pseudomonas aeruginosa.


Journal

Applied and environmental microbiology
ISSN: 1098-5336
Titre abrégé: Appl Environ Microbiol
Pays: United States
ID NLM: 7605801

Informations de publication

Date de publication:
28 06 2023
Historique:
medline: 30 6 2023
pubmed: 18 5 2023
entrez: 18 5 2023
Statut: ppublish

Résumé

Inducible gene expression systems are powerful genetic tools to study bacterial physiology, probing essential and toxic gene functions, gene dosage effects, and overexpression phenotypes. For the opportunistic human pathogen Pseudomonas aeruginosa, dedicated inducible gene expression systems are scarce. In the current study, we developed a minimal synthetic 4-isopropylbenzoic acid (cumate)-inducible promoter, called P

Identifiants

pubmed: 37199671
doi: 10.1128/aem.00211-23
pmc: PMC10304978
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0021123

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

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Auteurs

Alexander Klotz (A)

Biozentrum, University of Basel, Basel, Switzerland.

Andreas Kaczmarczyk (A)

Biozentrum, University of Basel, Basel, Switzerland.

Urs Jenal (U)

Biozentrum, University of Basel, Basel, Switzerland.

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Classifications MeSH