Persisting symptoms after Cryptosporidium hominis outbreak: a 10-year follow-up from Östersund, Sweden.


Journal

Parasitology research
ISSN: 1432-1955
Titre abrégé: Parasitol Res
Pays: Germany
ID NLM: 8703571

Informations de publication

Date de publication:
Jul 2023
Historique:
received: 22 03 2023
accepted: 08 05 2023
medline: 19 6 2023
pubmed: 18 5 2023
entrez: 18 5 2023
Statut: ppublish

Résumé

In late 2010, an outbreak of Cryptosporidium hominis affected 27,000 inhabitants (45%) of Östersund, Sweden. Previous research shows that abdomen and joint symptoms commonly persist up to 5 years post-infection. It is unknown whether Cryptosporidium is associated with sequelae for a longer duration, how persisting symptoms present over time, and whether sequelae are associated with prolonged infection. In this prospective cohort study, a randomly selected cohort in Östersund was surveyed about cryptosporidiosis symptoms in 2011 (response rate 69.2%). A case was defined as a respondent reporting new diarrhoea episodes during the outbreak. Follow-up questionnaires were sent after 5 and 10 years. Logistic regressions were used to examine associations between case status and symptoms reported after 10 years, with results presented as adjusted odds ratios (aOR) with 95% confidence intervals. Consistency of symptoms and associations with case status and number of days with symptoms during outbreak were analysed using X

Identifiants

pubmed: 37199767
doi: 10.1007/s00436-023-07866-8
pii: 10.1007/s00436-023-07866-8
pmc: PMC10193336
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1631-1639

Informations de copyright

© 2023. The Author(s).

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Auteurs

Marije Boks (M)

Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden. marije.boks@umu.se.

Mikael Lilja (M)

Unit of Research, Education and Development - Östersund, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.

Micael Widerström (M)

Department of Clinical Microbiology, Umeå University, Umeå, Sweden.

Pontus Karling (P)

Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.

Anna Lindam (A)

Unit of Research, Education and Development - Östersund, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.

Malin Sjöström (M)

Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.

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Classifications MeSH