Role of p38 MAPK, Akt and NFκB in renoprotective effects of nebivolol on renal ischemia-reperfusion injury in rats.

Rats Male Animals p38 Mitogen-Activated Protein Kinases / metabolism NF-kappa B / metabolism Proto-Oncogene Proteins c-akt / metabolism Nebivolol / pharmacology Caspase 3 / metabolism Rats, Sprague-Dawley Rats, Wistar Reperfusion Injury / drug therapy Ischemia Inflammation / metabolism Kidney
Akt NFκB ischemia kidney nebivolol p38 MAPK rat renoprotection reperfusion

Journal

Biotechnic & histochemistry : official publication of the Biological Stain Commission
ISSN: 1473-7760
Titre abrégé: Biotech Histochem
Pays: England
ID NLM: 9107378

Informations de publication

Date de publication:
Nov 2023
Historique:
medline: 19 7 2023
pubmed: 22 5 2023
entrez: 22 5 2023
Statut: ppublish

Résumé

Renal ischemia-reperfusion (I-R) injury is a complex pathophysiologic condition characterized by oxidative stress, inflammation and apoptosis. We investigated the potential renoprotective effect of nebivolol, a β

Identifiants

DOI: 10.1080/10520295.2023.2212412 PMID: 37211827
pubmed: 37211827
doi: 10.1080/10520295.2023.2212412
doi:

Substances chimiques

p38 Mitogen-Activated Protein Kinases EC 2.7.11.24
NF-kappa B 0
Proto-Oncogene Proteins c-akt EC 2.7.11.1
Nebivolol 030Y90569U
Caspase 3 EC 3.4.22.-

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

401-411

Auteurs

Zahide Cavdar (Z)

Department of Molecular Medicine, Health Sciences Institute, Dokuz Eylül University, Izmir, Turkey.
ORCID: 0000-0002-5457-198X

Ayse Kocak (A)

Department of Molecular Medicine, Health Sciences Institute, Dokuz Eylül University, Izmir, Turkey.

Cemre Ural (C)

Department of Molecular Medicine, Health Sciences Institute, Dokuz Eylül University, Izmir, Turkey.
ORCID: 0000-0002-4613-4528

Aysan Afagh (A)

Department of Molecular Medicine, Health Sciences Institute, Dokuz Eylül University, Izmir, Turkey.

Sibel Ersan (S)

Department of Nephrology, Izmir Tepecik Research and Training Hospital, Izmir, Turkey.

Seda Ozbal (S)

Department of Histology and Embryology, Faculty of Medicine, Dokuz Eylül University, Izmir, Turkey.

Merve Tatli (M)

Department of Histology and Embryology, Faculty of Medicine, Dokuz Eylül University, Izmir, Turkey.

Asli Celik (A)

Department of Laboratory Animal Science, Health Sciences Institute, Dokuz Eylül University, Izmir, Turkey.

Sevki Arslan (S)

Department of Biology, Faculty of Science, Pamukkale University, Denizli, Turkey.
ORCID: 0000-0002-4215-5006

Caner Cavdar (C)

Department of Nephrology, Faculty of Medicine, Dokuz Eylül University, Izmir, Turkey.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Role of p38 MAPK, Akt and NFκB in...
questionsmedicales.fr › Eucaryotes › Animaux › Role of p38 MAPK, Akt and NFκB in...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protein-Serine-Threonine Kinases › Mitogen-Activated Protein Kinases › p38 Mitogen-Activated Protein Kinases › Role of p38 MAPK, Akt and NFκB in...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteur de transcription NF-kappa B › Role of p38 MAPK, Akt and NFκB in...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines tumorales › Protéines oncogènes › Protéines proto-oncogènes › Protéines proto-oncogènes c-akt › Role of p38 MAPK, Akt and NFκB in...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Benzopyranes › Nébivolol › Role of p38 MAPK, Akt and NFκB in...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protéines régulatrices de l'apoptose › Caspases › Caspases effectrices › Caspase-3 › Role of p38 MAPK, Akt and NFκB in...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Rat Sprague-Dawley › Role of p38 MAPK, Akt and NFκB in...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Rat Wistar › Role of p38 MAPK, Akt and NFκB in...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Complications postopératoires › Lésion d'ischémie-reperfusion › Role of p38 MAPK, Akt and NFκB in...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Ischémie › Role of p38 MAPK, Akt and NFκB in...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Inflammation › Role of p38 MAPK, Akt and NFκB in...
questionsmedicales.fr › Appareil urogénital › Voies urinaires › Rein › Role of p38 MAPK, Akt and NFκB in...