Time trajectories of key cardiometabolic parameters and of cardiovascular risk in subjects with diabetes in a real world setting.
Cardiometabolic parameters
Diabetes
Time trajectories
UKPDS risk Engine
Journal
Diabetes & metabolic syndrome
ISSN: 1878-0334
Titre abrégé: Diabetes Metab Syndr
Pays: Netherlands
ID NLM: 101462250
Informations de publication
Date de publication:
Jun 2023
Jun 2023
Historique:
received:
20
05
2022
revised:
07
04
2023
accepted:
28
04
2023
medline:
19
6
2023
pubmed:
23
5
2023
entrez:
22
5
2023
Statut:
ppublish
Résumé
Diabetes is associated with increased cardiovascular risk. Glycated haemoglobin (HbA We linked the diabetes electronic health records to the laboratory information system so as to investigate the trajectories of key metabolic parameters from 3 years prior to the diagnosis of diabetes to 10 years after diagnosis. We calculated the cardiovascular risk at the different time points during this period using the United Kingdom Prospective Study (UKPDS) risk engine. The study included 21,288 patients. The median age at diagnosis was 56 years and 55.3% were male. There was a sharp decrease in HbA Our data suggest that lipid control should be tightened with increasing duration of diabetes since this is more readily achievable than HbA
Sections du résumé
BACKGROUND AND AIMS
OBJECTIVE
Diabetes is associated with increased cardiovascular risk. Glycated haemoglobin (HbA
METHODS
METHODS
We linked the diabetes electronic health records to the laboratory information system so as to investigate the trajectories of key metabolic parameters from 3 years prior to the diagnosis of diabetes to 10 years after diagnosis. We calculated the cardiovascular risk at the different time points during this period using the United Kingdom Prospective Study (UKPDS) risk engine.
RESULTS
RESULTS
The study included 21,288 patients. The median age at diagnosis was 56 years and 55.3% were male. There was a sharp decrease in HbA
CONCLUSIONS
CONCLUSIONS
Our data suggest that lipid control should be tightened with increasing duration of diabetes since this is more readily achievable than HbA
Identifiants
pubmed: 37216853
pii: S1871-4021(23)00073-5
doi: 10.1016/j.dsx.2023.102777
pii:
doi:
Substances chimiques
Lipids
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
102777Informations de copyright
Copyright © 2023 Research Trust of DiabetesIndia (DiabetesIndia) and National Diabetes Obesity and Cholesterol Foundation (N-DOC). Published by Elsevier Ltd. All rights reserved.