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High-quality and high-resolution magnetic resonance (MR) images can provide more details for diagnosis and analyses. Recently, MR images guided neurosurgery has become an emerging technique in clinics. Unlike other medical imaging techniques, it is impossible to achieve both real-time imaging and high image quality in MR imaging. The real-time performance is closely related to the nuclear magnetic equipment itself as well as the collection strategy of the k space data. Optimizing the imaging time cost via the corresponding algorithm is harder than enhancing image quality. Further, in reconstructing low-resolution and noise-rich MR images, getting relatively high-definition and resolution MR images as references are difficult or impossible. In addition, the existing methods are restricted in learning the controllable functions under the supervision of known degradation types and levels. As a result, severely bad results are inevitable when the modeling assumptions are far apart from the actual situation. To address these problems, we propose a novel adaptive adjustment method based on real MR images via opinion-unaware measurements for real super-resolution (A

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Copyright © 2023. Published by Elsevier Ltd.

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Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.