Equity and bias in electronic health records data.
Community engagement
Health equity
Health literacy
Patient-reported outcomes
Social determinants of health
Journal
Contemporary clinical trials
ISSN: 1559-2030
Titre abrégé: Contemp Clin Trials
Pays: United States
ID NLM: 101242342
Informations de publication
Date de publication:
07 2023
07 2023
Historique:
received:
13
03
2023
revised:
20
04
2023
accepted:
19
05
2023
pmc-release:
01
07
2024
medline:
14
6
2023
pubmed:
25
5
2023
entrez:
24
5
2023
Statut:
ppublish
Résumé
Embedded pragmatic clinical trials (ePCTs) are conducted during routine clinical care and have the potential to increase knowledge about the effectiveness of interventions under real world conditions. However, many pragmatic trials rely on data from the electronic health record (EHR) data, which are subject to bias from incomplete data, poor data quality, lack of representation from people who are medically underserved, and implicit bias in EHR design. This commentary examines how the use of EHR data might exacerbate bias and potentially increase health inequities. We offer recommendations for how to increase generalizability of ePCT results and begin to mitigate bias to promote health equity.
Identifiants
pubmed: 37225122
pii: S1551-7144(23)00161-1
doi: 10.1016/j.cct.2023.107238
pmc: PMC10330606
mid: NIHMS1905043
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
107238Subventions
Organisme : NCCIH NIH HHS
ID : UH3 AT009838
Pays : United States
Organisme : NIAMS NIH HHS
ID : UH3 AR076387
Pays : United States
Organisme : NIA NIH HHS
ID : UH3 AG067593
Pays : United States
Organisme : NIDA NIH HHS
ID : UG3 DA047003
Pays : United States
Organisme : NCCIH NIH HHS
ID : UG3 AT009844
Pays : United States
Organisme : NHLBI NIH HHS
ID : UH3 HL144163
Pays : United States
Organisme : NCCIH NIH HHS
ID : U24 AT010961
Pays : United States
Organisme : NCCIH NIH HHS
ID : UH3 AT011265
Pays : United States
Organisme : NCCIH NIH HHS
ID : UH3 AT010739
Pays : United States
Organisme : NCCIH NIH HHS
ID : UH3 AT010621
Pays : United States
Organisme : NCCIH NIH HHS
ID : UG3 AT009838
Pays : United States
Organisme : NCCIH NIH HHS
ID : UG3 AT010621
Pays : United States
Organisme : NIDA NIH HHS
ID : UH3 DA047003
Pays : United States
Organisme : NIAMS NIH HHS
ID : UG3 AR076387
Pays : United States
Organisme : NHLBI NIH HHS
ID : UG3 HL144163
Pays : United States
Organisme : NCCIH NIH HHS
ID : UG3 AT011265
Pays : United States
Organisme : NINR NIH HHS
ID : UH3 NR019943
Pays : United States
Organisme : NCCIH NIH HHS
ID : UH3 AT009844
Pays : United States
Organisme : NIA NIH HHS
ID : UG3 AG067593
Pays : United States
Organisme : NCCIH NIH HHS
ID : UG3 AT010739
Pays : United States
Organisme : NINR NIH HHS
ID : UG3 NR019943
Pays : United States
Informations de copyright
Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest ECO Reports grants to her institution from Pfizer, BMS, and Novartis. KM reports grants and contracts to his institution from Novartis, Amgen, Seqirus, Genentech, BMS, and Boehringer Ingelheim. ADB reports grants from Alike Health, travel from Microsoft. All other authors have nothing to disclose.
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