Loop2 Size Modification Reveals Significant Impacts on the Potency of α-Conotoxin TxID.

Rats Animals Conotoxins / chemistry Conus Snail / chemistry Receptors, Nicotinic / metabolism Alanine Nicotinic Antagonists / pharmacology
CD spectra electrophysiology loop size modification α-conotoxin TxID α3β4 nAChR

Journal

Marine drugs
ISSN: 1660-3397
Titre abrégé: Mar Drugs
Pays: Switzerland
ID NLM: 101213729

Informations de publication

Date de publication:
01 May 2023
Historique:
received: 05 04 2023
revised: 27 04 2023
accepted: 29 04 2023
medline: 29 5 2023
pubmed: 26 5 2023
entrez: 26 5 2023
Statut: epublish

Résumé

α4/6-conotoxin TxID, which was identified from

Identifiants

DOI: 10.3390/md21050286 PMID: 37233480 PMC: PMC10222858
pubmed: 37233480
pii: md21050286
doi: 10.3390/md21050286
pmc: PMC10222858
pii:
doi:

Substances chimiques

Conotoxins 0
Receptors, Nicotinic 0
Alanine OF5P57N2ZX
Nicotinic Antagonists 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Guangxi Natural Science Foundation
ID : 2022GXNSFBA035662
Organisme : Guangxi Science and Technology Base & Talents Fund
ID : GUIKE AD22035948
Organisme : Major Intergovernmental Joint Research Project of National Key R & D Program of China
ID : 2022YFE0132700
Organisme : the 111 Project
ID : D20010
Organisme : the National Natural Science Foundation of China
ID : 82104059
Organisme : the National Natural Science Foundation of China
ID : 81872794
Organisme : the National Natural Science Foundation of China
ID : 41966003

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Auteurs

Jianying Dong (J)

School of Medicine, Guangxi University, Nanning 530004, China.

Panpan Zhang (P)

School of Medicine, Guangxi University, Nanning 530004, China.

Junjie Xie (J)

School of Medicine, Guangxi University, Nanning 530004, China.

Ting Xie (T)

School of Medicine, Guangxi University, Nanning 530004, China.

Xiaopeng Zhu (X)

School of Medicine, Guangxi University, Nanning 530004, China.
ORCID: 0000-0001-8830-4954

Dongting Zhangsun (D)

Key Laboratory of Tropical Biological Resources, Ministry of Education, Key Laboratory for Marine Drugs of Haikou, Hainan University, Haikou 570228, China.

Jinpeng Yu (J)

School of Medicine, Guangxi University, Nanning 530004, China.

Sulan Luo (S)

School of Medicine, Guangxi University, Nanning 530004, China.
Key Laboratory of Tropical Biological Resources, Ministry of Education, Key Laboratory for Marine Drugs of Haikou, Hainan University, Haikou 570228, China.
ORCID: 0000-0002-9358-5970

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Loop2 Size Modification Reveals Significant...
questionsmedicales.fr › Eucaryotes › Animaux › Loop2 Size Modification Reveals Significant...
questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Venins › Venins de mollusque › Conotoxines › Loop2 Size Modification Reveals Significant...
questionsmedicales.fr › Eucaryotes › Animaux › Invertébrés › Mollusca › Gastropoda › Conus › Loop2 Size Modification Reveals Significant...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux neuromédiateurs › Récepteurs cholinergiques › Récepteurs nicotiniques › Loop2 Size Modification Reveals Significant...
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Alanine › Loop2 Size Modification Reveals Significant...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Agents neuromédiateurs › Agents cholinergiques › Antagonistes cholinergiques › Antagonistes nicotiniques › Loop2 Size Modification Reveals Significant...