Total Chemical Synthesis of Glycosylated TREM2 Ectodomain.

Animals Humans Alzheimer Disease / metabolism Glycosylation Phagocytosis Microglia / metabolism Mutation Mammals / metabolism Membrane Glycoproteins / genetics Receptors, Immunologic / genetics
Alzheimer’s disease TREM2 glycosylation native chemical ligation

Journal

ACS chemical neuroscience
ISSN: 1948-7193
Titre abrégé: ACS Chem Neurosci
Pays: United States
ID NLM: 101525337

Informations de publication

Date de publication:
07 06 2023
Historique:
medline: 8 6 2023
pubmed: 26 5 2023
entrez: 26 5 2023
Statut: ppublish

Résumé

Mutations in a microglia-associated gene

Identifiants

DOI: 10.1021/acschemneuro.3c00257 PMID: 37235776
pubmed: 37235776
doi: 10.1021/acschemneuro.3c00257
doi:

Substances chimiques

TREM2 protein, human 0
Membrane Glycoproteins 0
Receptors, Immunologic 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2243-2251

Subventions

Organisme : NIA NIH HHS
ID : P01 AG002132
Pays : United States
Organisme : NIGMS NIH HHS
ID : R24 GM137786
Pays : United States
Organisme : NIA NIH HHS
ID : R15 AG080493
Pays : United States
Organisme : NIGMS NIH HHS
ID : P20 GM113117
Pays : United States

Auteurs

Gayani Wijegunawardena (G)

Department of Chemistry and Biochemistry, Wichita State University, Wichita, Kansas 67260, United States.

Erika Castillo (E)

Institute for Neurodegenerative Diseases, University of California, San Francisco, California 94158, United States.
ORCID: 0000-0003-2492-901X

Brandy Henrickson (B)

Department of Chemistry and Biochemistry, Wichita State University, Wichita, Kansas 67260, United States.

Regan Davis (R)

Department of Chemistry and Biochemistry, Wichita State University, Wichita, Kansas 67260, United States.

Carlo Condello (C)

Institute for Neurodegenerative Diseases, University of California, San Francisco, California 94158, United States.
Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, California 94158, United States.

Haifan Wu (H)

Department of Chemistry and Biochemistry, Wichita State University, Wichita, Kansas 67260, United States.
ORCID: 0000-0002-2050-9950

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Total Chemical Synthesis of Glycosylated TREM2...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Total Chemical Synthesis of Glycosylated TREM2...
questionsmedicales.fr › Troubles mentaux › Troubles neurocognitifs › Démence › Maladie d'Alzheimer › Total Chemical Synthesis of Glycosylated TREM2...
questionsmedicales.fr › Métabolisme › Métabolisme glucidique › Glycosylation › Total Chemical Synthesis of Glycosylated TREM2...
questionsmedicales.fr › Phénomènes du système immunitaire › Phagocytose › Total Chemical Synthesis of Glycosylated TREM2...
questionsmedicales.fr › Cellules › Névroglie › Microglie › Total Chemical Synthesis of Glycosylated TREM2...
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Mutation › Total Chemical Synthesis of Glycosylated TREM2...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Total Chemical Synthesis of Glycosylated TREM2...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Glycoprotéines membranaires › Total Chemical Synthesis of Glycosylated TREM2...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs immunologiques › Total Chemical Synthesis of Glycosylated TREM2...