Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox.
MPXV
T cells
VACV
infectious diseases
long-lived memory T cells
monkeypox
mpox
vaccinia virus
viral immunity
Journal
Cell host & microbe
ISSN: 1934-6069
Titre abrégé: Cell Host Microbe
Pays: United States
ID NLM: 101302316
Informations de publication
Date de publication:
14 06 2023
14 06 2023
Historique:
received:
28
02
2023
revised:
06
04
2023
accepted:
19
04
2023
medline:
19
6
2023
pubmed:
27
5
2023
entrez:
26
5
2023
Statut:
ppublish
Résumé
Mpox represents a persistent health concern with varying disease severity. Reinfections with mpox virus (MPXV) are rare, possibly indicating effective memory responses to MPXV or related poxviruses, notably vaccinia virus (VACV) from smallpox vaccination. We assessed cross-reactive and virus-specific CD4
Identifiants
pubmed: 37236191
pii: S1931-3128(23)00166-X
doi: 10.1016/j.chom.2023.04.015
pmc: PMC10211501
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
928-936.e4Subventions
Organisme : NIAID NIH HHS
ID : 75N93019C00065
Pays : United States
Informations de copyright
Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of interests M.B. is a consultant for Oxford Immunotec, Mabtech, Bristol-Myers Squibb, and MSD.
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