Generation of a Yeast Cell Model Potentially Useful to Identify the Mammalian Mitochondrial


Journal

Biomolecules
ISSN: 2218-273X
Titre abrégé: Biomolecules
Pays: Switzerland
ID NLM: 101596414

Informations de publication

Date de publication:
10 05 2023
Historique:
received: 24 04 2023
revised: 07 05 2023
accepted: 08 05 2023
medline: 29 5 2023
pubmed: 27 5 2023
entrez: 27 5 2023
Statut: epublish

Résumé

The human mitochondrial carrier family (MCF) consists of 53 members. Approximately one-fifth of them are still orphans of a function. Most mitochondrial transporters have been functionally characterized by reconstituting the bacterially expressed protein into liposomes and transport assays with radiolabeled compounds. The efficacy of this experimental approach is constrained to the commercial availability of the radiolabeled substrate to be used in the transport assays. A striking example is that of

Identifiants

pubmed: 37238678
pii: biom13050808
doi: 10.3390/biom13050808
pmc: PMC10216676
pii:
doi:

Substances chimiques

N-acetylglutamic acid MA61H539YZ
Arginine 94ZLA3W45F
Ornithine E524N2IXA3

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Ruggiero Gorgoglione (R)

Department of Bioscience, Biotechnology and Environment, University of Bari, 70125 Bari, Italy.

Roberta Seccia (R)

Department of Bioscience, Biotechnology and Environment, University of Bari, 70125 Bari, Italy.

Amer Ahmed (A)

Department of Bioscience, Biotechnology and Environment, University of Bari, 70125 Bari, Italy.

Angelo Vozza (A)

Department of Bioscience, Biotechnology and Environment, University of Bari, 70125 Bari, Italy.

Loredana Capobianco (L)

Department of Biological and Environmental Sciences and Technologies, University of Salento, 73100 Lecce, Italy.

Alessia Lodi (A)

Department of Nutritional Sciences, College of Natural Sciences, The University of Texas at Austin, Austin, TX 78712, USA.
Dell Pediatric Research Institute, Dell Medical School, The University of Texas at Austin, Austin, TX 78723, USA.

Federica Marra (F)

Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy.

Eleonora Paradies (E)

CNR Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies (IBIOM), 70125 Bari, Italy.

Luigi Palmieri (L)

Department of Bioscience, Biotechnology and Environment, University of Bari, 70125 Bari, Italy.

Vincenzo Coppola (V)

Department of Cancer Biology and Genetics, College of Medicine, The Ohio State University and Arthur G. James Comprehensive Cancer Center, Columbus, OH 43210, USA.

Vincenza Dolce (V)

Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy.

Giuseppe Fiermonte (G)

Department of Bioscience, Biotechnology and Environment, University of Bari, 70125 Bari, Italy.

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Classifications MeSH