Roles of inflammasomes in viral myocarditis.
cytokines
infection
inflammasome
interleukin-1β
viral myocarditis
Journal
Frontiers in cellular and infection microbiology
ISSN: 2235-2988
Titre abrégé: Front Cell Infect Microbiol
Pays: Switzerland
ID NLM: 101585359
Informations de publication
Date de publication:
2023
2023
Historique:
received:
23
01
2023
accepted:
28
03
2023
medline:
2
6
2023
pubmed:
31
5
2023
entrez:
31
5
2023
Statut:
epublish
Résumé
Viral myocarditis (VMC), characterized by viral infection-induced inflammation, is a life-threatening disease associated with dilated cardiomyopathy or heart failure. Innate immunity plays a crucial role in the progression of inflammation, in which inflammasomes provide a platform for the secretion of cytokines and mediate pyroptosis. Inflammasomes are rising stars gaining increasing attention. The nucleotide oligomerization domain-, leucine-rich repeat-, and pyrin domain-containing protein 3 (NLRP3) inflammasome, the caspase recruitment domain-containing protein 8 (CARD8) inflammasome, and the caspase-11 inflammasome are three inflammasomes that were reported to affect the process and prognosis of VMC. These inflammasomes can be activated by a wide range of cellular events. Accumulating evidence has suggested that inflammasomes are involved in different stages of VMC, including the trigger and progression of myocardial injury and remodeling after infection. In this review, we summarized the pathways involving inflammasomes in VMC and discussed the potential therapies targeting inflammasomes and related pathways.
Identifiants
pubmed: 37256114
doi: 10.3389/fcimb.2023.1149911
pmc: PMC10225676
doi:
Substances chimiques
Inflammasomes
0
NLR Family, Pyrin Domain-Containing 3 Protein
0
Apoptosis Regulatory Proteins
0
CARD8 protein, human
0
Neoplasm Proteins
0
CARD Signaling Adaptor Proteins
0
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1149911Informations de copyright
Copyright © 2023 Xu, Zhou, Zheng, Yang, Huang and Li.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
J Virol. 2008 Apr;82(7):3782-90
pubmed: 18216106
JAMA Cardiol. 2020 Jul 1;5(7):819-824
pubmed: 32219357
Circulation. 2003 Jun 10;107(22):2793-8
pubmed: 12771005
Nat Immunol. 2008 Aug;9(8):847-56
pubmed: 18604214
Cell Physiol Biochem. 2017;44(6):2269-2280
pubmed: 29262411
Nature. 2018 Aug;560(7717):198-203
pubmed: 30046112
Acta Histochem. 2021 Jan;123(1):151653
pubmed: 33246224
Immunology. 1998 Jun;94(2):263-70
pubmed: 9741351
Genes Dev. 1999 Apr 15;13(8):1015-24
pubmed: 10215628
Cardiovasc Res. 2020 May 1;116(6):1097-1100
pubmed: 32227090
J Exp Med. 2022 Oct 3;219(10):
pubmed: 36129454
Cardiovasc Res. 2003 Oct 15;60(1):11-25
pubmed: 14522403
J Heart Lung Transplant. 2003 Feb;22(2):214-7
pubmed: 12581773
Circulation. 2001 Aug 28;104(9):1076-82
pubmed: 11524405
Eur J Heart Fail. 2004 Mar 1;6(2):137-44
pubmed: 14984720
Sci Signal. 2010 Jan 19;3(105):cm1
pubmed: 20086235
Annu Rev Immunol. 2022 Apr 26;40:323-348
pubmed: 35113729
Physiol Rev. 2018 Jan 1;98(1):505-553
pubmed: 29351514
Mediators Inflamm. 2018 Mar 4;2018:6054069
pubmed: 29686531
Physiol Rev. 2003 Jul;83(3):731-801
pubmed: 12843408
Eur Heart J. 2020 May 14;41(19):1804-1806
pubmed: 32293672
Cardiovasc Res. 2003 Oct 15;60(1):5-10
pubmed: 14522402
N Engl J Med. 2009 Apr 9;360(15):1526-38
pubmed: 19357408
Cells. 2019 Dec 03;8(12):
pubmed: 31816901
Front Pediatr. 2021 Jan 18;8:635080
pubmed: 33537271
Cell. 2007 Dec 14;131(6):1047-58
pubmed: 18083096
Am J Physiol Heart Circ Physiol. 2014 Nov 15;307(10):H1438-47
pubmed: 25260607
mBio. 2019 Feb 5;10(1):
pubmed: 30723129
ESC Heart Fail. 2022 Apr;9(2):925-941
pubmed: 35178861
J Virol. 2010 Jan;84(1):254-60
pubmed: 19846534
Circulation. 1996 Dec 1;94(11):2930-7
pubmed: 8941123
Cell Mol Biol Lett. 2019 Dec 04;24:66
pubmed: 31844417
J Exp Med. 2016 May 2;213(5):771-90
pubmed: 27069117
Am J Physiol Heart Circ Physiol. 2011 Sep;301(3):H841-7
pubmed: 21666116
J Mol Cell Cardiol. 2010 Mar;48(3):468-73
pubmed: 19729021
Nature. 2014 Oct 9;514(7521):187-92
pubmed: 25119034
Immunity. 2011 Feb 25;34(2):213-23
pubmed: 21349431
Circulation. 2007 Jan 2;115(1):94-102
pubmed: 17190866
PLoS Pathog. 2018 Jan 23;14(1):e1006872
pubmed: 29360865
J Atheroscler Thromb. 2017 May 1;24(5):443-451
pubmed: 28260724
Science. 2013 Sep 13;341(6151):1246-9
pubmed: 23887873
Cell Commun Signal. 2021 Nov 3;19(1):107
pubmed: 34732218
Cell. 2006 Feb 24;124(4):823-35
pubmed: 16497591
J Immunol. 2003 May 1;170(9):4731-7
pubmed: 12707353
J Immunother Cancer. 2018 Jun 15;6(1):56
pubmed: 29907163
Mol Immunol. 2016 Jun;74:47-58
pubmed: 27148820
Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20446-51
pubmed: 19074283
J Pathol. 1996 Dec;180(4):450-4
pubmed: 9014868
J Biol Chem. 2001 Jan 5;276(1):125-32
pubmed: 11016935
Heart Rhythm. 2020 Sep;17(9):1463-1471
pubmed: 32387246
Immunol Res. 2008;42(1-3):3-18
pubmed: 18626576
J Clin Invest. 2015 Jun;125(6):2458-62
pubmed: 25938787
Lab Invest. 2004 Feb;84(2):173-81
pubmed: 14688801
Herz. 2020 May;45(3):230-232
pubmed: 32140732
PLoS One. 2012;7(5):e35144
pubmed: 22574112
Cardiovasc Revasc Med. 2021 Feb;23:107-113
pubmed: 32847728
Annu Rev Immunol. 2022 Apr 26;40:249-269
pubmed: 35080918
Cell Death Differ. 2007 Sep;14(9):1590-604
pubmed: 17599095
Nature. 2004 Jul 8;430(6996):213-8
pubmed: 15190255
Circ Res. 2020 Apr 24;126(9):1260-1280
pubmed: 32324502
Trends Biochem Sci. 2023 Apr;48(4):331-344
pubmed: 36336552
J Virol. 2017 Mar 29;91(8):
pubmed: 28148804
Nat Immunol. 2012 Mar 19;13(4):333-42
pubmed: 22430786
J Am Coll Cardiol. 1999 Apr;33(5):1400-7
pubmed: 10193745
Cell Mol Biol Lett. 2020 Feb 19;25:6
pubmed: 32099552
Int J Mol Sci. 2020 Nov 10;21(22):
pubmed: 33182829
Proc Natl Acad Sci U S A. 2015 Oct 27;112(43):13237-42
pubmed: 26464513
J Biol Chem. 2002 Jun 14;277(24):21119-22
pubmed: 11967258
Circ Heart Fail. 2017 Sep;10(9):
pubmed: 28912259
Sci Rep. 2022 Nov 22;12(1):20077
pubmed: 36418383
Nat Commun. 2017 Aug 4;8(1):202
pubmed: 28779175
J Clin Immunol. 2009 Nov;29(6):730-7
pubmed: 19826933
Am J Emerg Med. 2020 Jul;38(7):1504-1507
pubmed: 32317203
JAMA Cardiol. 2020 Nov 1;5(11):1281-1285
pubmed: 32730555
Nat Immunol. 2021 May;22(5):550-559
pubmed: 33707781
Basic Res Cardiol. 2019 Jan 23;114(2):11
pubmed: 30673858
FASEB J. 2019 Jan;33(1):942-952
pubmed: 30080445
Nature. 2009 Mar 26;458(7237):514-8
pubmed: 19158675
Clin Respir J. 2017 Nov;11(6):859-866
pubmed: 26663885
Lancet Respir Med. 2020 Jul;8(7):681-686
pubmed: 32473124
Circulation. 2020 Nov 10;142(19):1865-1870
pubmed: 32997947
Crit Care Med. 2016 Aug;44(8):1630-1
pubmed: 27428134
Front Med (Lausanne). 2015 Apr 08;2:21
pubmed: 25905103
Cell. 2006 Feb 24;124(4):783-801
pubmed: 16497588
Stem Cell Rev Rep. 2021 Feb;17(1):266-277
pubmed: 32691370
Front Physiol. 2018 Apr 11;9:382
pubmed: 29695980
N Engl J Med. 2017 Sep 21;377(12):1119-1131
pubmed: 28845751
Basic Res Cardiol. 2022 Aug 23;117(1):40
pubmed: 35997820
Int J Cardiol. 2016 Aug 1;216:58-65
pubmed: 27140338
N Engl J Med. 2022 Oct 20;387(16):1488-1500
pubmed: 36260793
Nat Med. 2015 Jul;21(7):677-87
pubmed: 26121197
Rev Esp Cardiol (Engl Ed). 2020 Jun;73(6):503-504
pubmed: 32345547
Hum Vaccin Immunother. 2014;10(5):1284-94
pubmed: 24614684
J Virol. 2002 Apr;76(7):3365-73
pubmed: 11884562
Nat Rev Cardiol. 2015 Nov;12(11):670-80
pubmed: 26194549
Antiviral Res. 2015 Jul;119:68-77
pubmed: 25956163
Life Sci Alliance. 2018 Dec 6;1(6):e201800237
pubmed: 30564782
Can J Cardiol. 2020 Jul;36(7):1068-1080
pubmed: 32425328
PLoS One. 2011;6(9):e25212
pubmed: 21966458
J Biol Chem. 2011 Jan 7;286(1):35-41
pubmed: 21051542
Signal Transduct Target Ther. 2021 Sep 6;6(1):338
pubmed: 34489396
Rev Med Virol. 2020 Nov;30(6):1-14
pubmed: 32720461
Card Electrophysiol Clin. 2022 Mar;14(1):53-62
pubmed: 35221085
Nat Rev Immunol. 2015 Feb;15(2):87-103
pubmed: 25614319
Cardiovasc Res. 2021 Nov 22;117(13):2639-2651
pubmed: 34117866
Prog Cardiovasc Dis. 1985 May-Jun;27(6):373-94
pubmed: 2988014
J Immunol. 1992 Dec 1;149(11):3535-41
pubmed: 1385527
Cardiology. 2020;145(3):187-198
pubmed: 31968347
J Cell Mol Med. 2020 Nov;24(21):12341-12354
pubmed: 33047847
Pharmacol Ther. 2020 May;209:107511
pubmed: 32097669
Cell Death Differ. 2002 Apr;9(4):358-61
pubmed: 11965488
Am J Pathol. 2004 Dec;165(6):1883-94
pubmed: 15579433
Am J Physiol Heart Circ Physiol. 2004 Oct;287(4):H1730-9
pubmed: 15165989
J Immunol. 2009 Jul 15;183(2):787-91
pubmed: 19570822
Yonsei Med J. 2016 Jan;57(1):5-14
pubmed: 26632377
Circulation. 2020 May 19;141(20):1648-1655
pubmed: 32200663
J Clin Pharm Ther. 2021 Jun;46(3):862-864
pubmed: 33403664
J Clin Invest. 1993 Apr;91(4):1327-36
pubmed: 8097205
Cancers (Basel). 2020 Nov 10;12(11):
pubmed: 33182653
Nat Rev Immunol. 2013 Jun;13(6):397-411
pubmed: 23702978
Cytokine Growth Factor Rev. 2021 Oct;61:2-15
pubmed: 34183243
Nat Immunol. 2013 May;14(5):454-60
pubmed: 23502856
Ann Rheum Dis. 2006 Aug;65(8):1006-12
pubmed: 16396977
J Exp Med. 2022 Oct 3;219(10):
pubmed: 36129453
Physiol Rev. 2007 Oct;87(4):1285-342
pubmed: 17928585
Virology. 2010 May 25;401(1):42-8
pubmed: 20206372
J Immunol. 2015 Aug 15;195(4):1685-97
pubmed: 26195813
EMBO Mol Med. 2018 Feb;10(2):200-218
pubmed: 29295868
Science. 2013 Sep 13;341(6151):1250-3
pubmed: 24031018
Nat Struct Biol. 2001 Oct;8(10):874-8
pubmed: 11573093
Genes Cells. 1999 Jun;4(6):353-62
pubmed: 10421844
Rev Med Virol. 2020 Nov;30(6):1-9
pubmed: 32845568
Trends Mol Med. 2022 May;28(5):421-434
pubmed: 35341684
Front Immunol. 2022 Apr 07;13:834289
pubmed: 35464402
Nature. 2012 Dec 6;492(7427):123-7
pubmed: 23143333
Cell. 2004 Jan 23;116(2):281-97
pubmed: 14744438
J Mol Cell Cardiol. 2018 Dec;125:149-161
pubmed: 30393107
Cell. 2020 Apr 16;181(2):271-280.e8
pubmed: 32142651
Apoptosis. 2007 Mar;12(3):513-24
pubmed: 17195095
Science. 2008 May 2;320(5876):674-7
pubmed: 18403674
Diabetes. 2016 Jan;65(1):255-68
pubmed: 26470784
Lancet. 2012 Feb 25;379(9817):738-47
pubmed: 22185868
Prog Cardiovasc Dis. 2010 Jan-Feb;52(4):274-88
pubmed: 20109598
Eur Heart J. 1995 Dec;16 Suppl O:150-2
pubmed: 8682086
PLoS One. 2012;7(9):e46515
pubmed: 23029542
Nature. 2011 Jan 13;469(7329):221-5
pubmed: 21124315
Nat Rev Cardiol. 2021 Mar;18(3):169-193
pubmed: 33046850
Am J Transl Res. 2020 May 15;12(5):1954-1964
pubmed: 32509190
Immunol Rev. 2018 Jan;281(1):99-114
pubmed: 29247998
Nat Immunol. 2009 Mar;10(3):266-72
pubmed: 19158679
Crit Care Med. 2016 Aug;44(8):e751-4
pubmed: 27031379
Nat Immunol. 2014 Dec;15(12):1126-33
pubmed: 25326752
Methods. 2007 Jan;41(1):118-22
pubmed: 17161308
Immunol Rev. 2020 Sep;297(1):13-25
pubmed: 32558991