A prospective comparison of UK and Malaysian patients with irritable bowel syndrome in secondary care.
Journal
Alimentary pharmacology & therapeutics
ISSN: 1365-2036
Titre abrégé: Aliment Pharmacol Ther
Pays: England
ID NLM: 8707234
Informations de publication
Date de publication:
07 2023
07 2023
Historique:
revised:
18
04
2023
received:
22
03
2023
accepted:
16
05
2023
medline:
26
6
2023
pubmed:
1
6
2023
entrez:
1
6
2023
Statut:
ppublish
Résumé
The prevalence of irritable bowel syndrome (IBS) is now known to be similar in various geographical regions, but there has been no study directly comparing characteristics of patients with IBS between populations. To evaluate clinical and psychological differences between adults with IBS seen in secondary care in the United Kingdom (UK) and Malaysia. Age- and sex-matched patients with IBS from a single centre in the UK (Leeds) and two centres in Malaysia (Kuala Lumpur and Kota Bharu), who fulfilled Rome III criteria, were recruited prospectively. Demographic characteristics and gastrointestinal and psychological symptoms were compared between both groups. A total of 266 (133 UK and 133 Malaysian) age- and sex-matched patients with Rome III IBS were recruited (mean age: 45.1 years Malaysia, vs. 46.5 years UK; 57.9% female). UK patients were more likely to consume alcohol than Malaysian patients (54.1% vs. 10.5%, p < 0.001). Compared with Malaysian patients, UK patients had more frequent abdominal pain, abdominal bloating, meal-related symptoms (p < 0.001 for all), higher symptom scores (mean 268.0 vs 166.0; p < 0.001), greater limitation of activities due to IBS (p = 0.007) and were more likely to report abnormal anxiety scores (p < 0.001). Higher perceived stress (mean 21.3 vs. 19.1, p = 0.014) and gastrointestinal symptom-specific anxiety scores (mean 50.8 vs. 43.0, p < 0.001) were also observed in UK patients. Finally, UK patients had higher somatoform symptom-reporting scores (mean 8.9 vs. 6.9, p < 0.001). IBS is more severe and is associated with a higher level of psychological symptoms in the UK compared with Malaysian patients in secondary care.
Sections du résumé
BACKGROUND
The prevalence of irritable bowel syndrome (IBS) is now known to be similar in various geographical regions, but there has been no study directly comparing characteristics of patients with IBS between populations.
AIMS
To evaluate clinical and psychological differences between adults with IBS seen in secondary care in the United Kingdom (UK) and Malaysia.
METHODS
Age- and sex-matched patients with IBS from a single centre in the UK (Leeds) and two centres in Malaysia (Kuala Lumpur and Kota Bharu), who fulfilled Rome III criteria, were recruited prospectively. Demographic characteristics and gastrointestinal and psychological symptoms were compared between both groups.
RESULTS
A total of 266 (133 UK and 133 Malaysian) age- and sex-matched patients with Rome III IBS were recruited (mean age: 45.1 years Malaysia, vs. 46.5 years UK; 57.9% female). UK patients were more likely to consume alcohol than Malaysian patients (54.1% vs. 10.5%, p < 0.001). Compared with Malaysian patients, UK patients had more frequent abdominal pain, abdominal bloating, meal-related symptoms (p < 0.001 for all), higher symptom scores (mean 268.0 vs 166.0; p < 0.001), greater limitation of activities due to IBS (p = 0.007) and were more likely to report abnormal anxiety scores (p < 0.001). Higher perceived stress (mean 21.3 vs. 19.1, p = 0.014) and gastrointestinal symptom-specific anxiety scores (mean 50.8 vs. 43.0, p < 0.001) were also observed in UK patients. Finally, UK patients had higher somatoform symptom-reporting scores (mean 8.9 vs. 6.9, p < 0.001).
CONCLUSIONS
IBS is more severe and is associated with a higher level of psychological symptoms in the UK compared with Malaysian patients in secondary care.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
168-174Commentaires et corrections
Type : CommentIn
Type : CommentIn
Informations de copyright
© 2023 The Authors. Alimentary Pharmacology & Therapeutics published by John Wiley & Sons Ltd.
Références
Mearin F, Lacy BE, Chang L, Chey WD, Lembo AJ, Simren M, et al. Bowel disorders. Gastroenterology. 2016;150:1393-407.
Ford AC, Forman D, Bailey AG, Axon ATR, Moayyedi P. Effect of dyspepsia on survival: a longitudinal 10-year follow-up study. Am J Gastroenterol. 2012;107:912-21.
Black CJ, Ford AC. Global burden of irritable bowel syndrome: trends, predictions and risk factors. Nat Rev Gastroenterol Hepatol. 2020;17(8):473-86.
Chuah KH, Cheong SY, Lim SZ, Mahadeva S. Functional dyspepsia leads to more healthcare utilization in secondary care compared with other functional gastrointestinal disorders. J Dig Dis. 2022;23(2):111-7.
Chuah KH, Beh KH, Mahamad Rappek NA, Mahadeva S. The epidemiology and quality of life of functional gastrointestinal disorders according to Rome III vs Rome IV criteria: a cross-sectional study in primary care. J Dig Dis. 2021;22(3):159-66.
Sperber AD, Bangdiwala SI, Drossman DA, Ghoshal UC, Simren M, Tack J, et al. Worldwide prevalence and burden of functional gastrointestinal disorders, results of Rome Foundation Global Study. Gastroenterology. 2021;160(1):99-114.e3.
Lovell RM, Ford AC. Global prevalence of, and risk factors for, irritable bowel syndrome: a meta-analysis. Clin Gastroenterol Hepatol. 2012;10:712-21.
Eijsbouts C, Zheng T, Kennedy NA, Bonfiglio F, Anderson CA, Moutsianas L, et al. Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders. Nat Genet. 2021;53(11):1543-52.
Zamani M, Alizadeh-Tabari S, Zamani V. Systematic review with meta-analysis: the prevalence of anxiety and depression in patients with irritable bowel syndrome. Aliment Pharmacol Ther. 2019;50(2):132-43.
Chuah KH, Mahadeva S. Cultural factors influencing functional gastrointestinal disorders in the east. J Neurogastroenterol Motil. 2018;24:536-43.
Chang FY, Lu CL, Chen TS. The current prevalence of irritable bowel syndrome in Asia. J Neurogastroenterol Motil. 2010;16(4):389-400.
Black CJ, Yiannakou Y, Houghton LA, Ford AC. Epidemiological, clinical, and psychological characteristics of individuals with self-reported irritable bowel syndrome based on the Rome IV vs Rome III criteria. Clin Gastroenterol Hepatol. 2020;18:392-8.
Black CJ, Yiannakou Y, Houghton LA, Shuweihdi F, West R, Guthrie E, et al. Anxiety-related factors associated with symptom severity in irritable bowel syndrome. Neurogastroenterol Motil. 2020;32:e13872.
Whitehead WE. Development and validation of the Rome III diagnostic questionnaire. In: Drossman DA, Corazziari E, Delvaux M, Spiller RC, Talley NJ, Thompson WG, et al., editors. Rome III: the functional gastrointestinal disorders. 3. McLean, Virginia: Degnon Associates; 2006. p. 835-53.
Palsson OS, Whitehead WE, van Tilburg MA, Chang L, Chey W, Crowell MD, et al. Rome IV diagnostic questionnaires and tables for investigators and clinicians. Gastroenterology. 2016;150:1481-91.
Lee YY, Waid A, Tan HJ, Chua SB, Whitehead WE. Validity and reliability of the Malay-language translation of the Rome III Diagnostic Questionnaire for irritable bowel syndrome. J Gastroenterol Hepatol. 2012;27(4):746-50.
Longstreth GF, Thompson WG, Chey WD, Houghton LA, Mearin F, Spiller RC. Functional bowel disorders. Gastroenterology. 2006;130(5):1480-91.
Francis CY, Morris J, Whorwell PJ. The irritable bowel severity scoring system: a simple method of monitoring irritable bowel syndrome and its progress. Aliment Pharmacol Ther. 1997;11:395-402.
Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67:361-70.
Fatt QK, Atiya AS, Heng NC, Beng CC. Validation of the hospital anxiety and depression scale and the psychological disorder among premature ejaculation subjects. Int J Impot Res. 2007;19(3):321-5.
Spiller RC, Humes DJ, Campbell E, Hastings M, Neal KR, Dukes GE, et al. The Patient Health Questionnaire 12 Somatic Symptom scale as a predictor of symptom severity and consulting behaviour in patients with irritable bowel syndrome and symptomatic diverticular disease. Aliment Pharmacol Ther. 2010;32:811-20.
Kroenke K, Spitzer RL, Williams JBW. The PHQ-15: validity of a new measure for evaluating the severity of somatic symptoms. Psychosom Med. 2002;64:258-66.
Ozolins U, Hale S, Cheng X, Hyatt A, Schofield P. Translation and back-translation methodology in health research-a critique. Expert Rev Pharmacoecon Outcomes Res. 2020;20(1):69-77.
Labus JS, Bolus R, Chang L, Wiklund I, Naesdal J, Mayer EA, et al. The Visceral Sensitivity Index: development and validation of a gastrointestinal symptom-specific anxiety scale. Aliment Pharmacol Ther. 2004;20:89-97.
Cohen S, Kamarck T, Mermelstein R. A global measure of perceived stress. J Health Soc Behav. 1983;24:385-96.
Sandhu SS, Ismail NH, Rampal KG. The Malay version of the perceived stress scale (PSS)-10 is a reliable and valid measure for stress among nurses in Malaysia. Malays J Med Sci. 2015;22(6):26-31.
Cohen S, Williamson G. Perceived stress in a probability sample of the united states. In: Spacapan S, Oskamp S, editors. The social psychology of health: claremont symposium on applied social psychology. Newbury Park, CA: Sage; 1988. p. 31-67.
Black CJ, Craig O, Gracie DJ, Ford AC. Comparison of the Rome IV criteria with the Rome III criteria for the diagnosis of irritable bowel syndrome in secondary care. Gut. 2021;70:1110-6.
Ghoshal UC, Rahman MM, Pratap N, Misra A, Sarker SA, Hasan M, et al. Comparisons of the Rome III and Rome IV criteria for diagnosis of irritable bowel syndrome in Indian and Bangladeshi communities and internal shifts in the diagnostic categories of bowel disorders of gut-brain interactions. Neurogastroenterol Motil. 2023;35:e14579.
Banerjee A, Sarkhel S, Sarkar R, Dhali GK. Anxiety and depression in irritable bowel syndrome. Indian J Psychol Med. 2017;39(6):741-5.
Drossman DA. Do psychosocial factors define symptom severity and patient status in irritable bowel syndrome? Am J Med. 1999;107(5a):41s-50s.
Fan WJ, Xu D, Chang M, Zhu LM, Fei GJ, Li XQ, et al. Predictors of healthcare-seeking behavior among Chinese patients with irritable bowel syndrome. World J Gastroenterol. 2017;23(42):7635-43.
Shiha MG, Asghar Z, Thoufeeq M, Kurien M, Ball AJ, Rej A, et al. Increased psychological distress and somatization in patients with irritable bowel syndrome compared with functional diarrhea or functional constipation, based on Rome IV criteria. Neurogastroenterol Motil. 2021;33(10):e14121.
Patel P, Bercik P, Morgan DG, Bolino C, Pintos-Sanchez MI, Moayyedi P, et al. Irritable bowel syndrome is significantly associated with somatisation in 840 patients, which may drive bloating. Aliment Pharmacol Ther. 2015;41(5):449-58.
Trindade IA, Melchior C, Tornblom H, Simren M. Quality of life in irritable bowel syndrome: exploring mediating factors through structural equation modelling. J Psychosom Res. 2022;159:110809.
Charatcharoenwitthaya P, Liangpunsakul S, Piratvisuth T. Alcohol-associated liver disease: east versus west. Clin Liver Dis. 2020;16(6):231-5.
Lim SZ, Chuah KH, Rajaram RB, Stanley K, Shahrani S, Chan WK, et al. Epidemiological trends of gastrointestinal and liver diseases in Malaysia: a single-center observational study. J Gastroenterol Hepatol. 2022;37(9):1732-40.
McKenzie YA, Bowyer RK, Leach H, Gulia P, Horobin J, O'Sullivan NA, et al. British Dietetic Association systematic review and evidence-based practice guidelines for the dietary management of irritable bowel syndrome in adults (2016 update). J Hum Nutr Diet. 2016;29(5):549-75.
Rakhra V, Galappaththy SL, Bulchandani S, Cabandugama PK. Obesity and the western diet: how we got here. Mo Med. 2020;117(6):536-8.
Miranda J, Vázquez-Polo M, Pérez-Junkera G, Fernández-Gil MDP, Bustamante MÁ, Navarro V, et al. FODMAP intake in Spanish population: open approach for risk assessment. Int J Environ Res Public Health. 2020;17(16):5882. https://doi.org/10.3390/ijerph17165882
Na W, Lee Y, Kim H, Kim YS, Sohn C. High-fat foods and FODMAPs containing gluten foods primarily contribute to symptoms of irritable bowel syndrome in Korean adults. Nutrients. 2021;13(4):1308. https://doi.org/10.3390/nu13041308
Wong Z, Mok CZ, Majid HA, Mahadeva S. Early experience with a low FODMAP diet in Asian patients with irritable bowel syndrome. JGH Open. 2018;2(5):178-81.
Black CJ, Staudacher HM, Ford AC. Efficacy of a low FODMAP diet in irritable bowel syndrome: systematic review and network meta-analysis. Gut. 2022;71:1117-26.
Vasant DH, Paine PA, Black CJ, Houghton LA, Everitt HA, Corsetti M, et al. British Society of Gastroenterology guidelines on the management of irritable bowel syndrome. Gut. 2021;70:1214-40.
Gwee KA, Gonlachanvit S, Ghoshal UC, Chua ASB, Miwa H, Wu J, et al. Second Asian consensus on irritable bowel syndrome. J Neurogastroenterol Motil. 2019;25(3):343-62.
Dong Y, Berens S, Eich W, Schaefert R, Tesarz J. Is body mass index associated with symptom severity and health-related quality of life in irritable bowel syndrome? A cross-sectional study. BMJ Open. 2018;8(10):e019453.
Wulan SN, Westerterp KR, Plasqui G. Ethnic differences in body composition and the associated metabolic profile: a comparative study between Asians and Caucasians. Maturitas. 2010;65(4):315-9.
Sperber AD, Bor S, Fang X, Bangdiwala SI, Drossman DA, Ghoshal UC, et al. Face-to-face interviews versus Internet surveys: comparison of two data collection methods in the Rome foundation global epidemiology study: implications for population-based research. Neurogastroenterol Motil. 2023;35(6):e14583.