Recurrence patterns among patients with sinonasal mucosal melanoma: A multi-institutional study.

Humans Female Male Nasal Mucosa Paranasal Sinus Neoplasms / surgery Disease-Free Survival Retrospective Studies Melanoma / therapy Neoplasm Recurrence, Local / epidemiology Survival Rate
cancer mucosal melanoma nasal cavity recurrence sinus

Journal

International forum of allergy & rhinology
ISSN: 2042-6984
Titre abrégé: Int Forum Allergy Rhinol
Pays: United States
ID NLM: 101550261

Informations de publication

Date de publication:
Dec 2023
Historique:
revised: 09 05 2023
received: 02 04 2023
accepted: 31 05 2023
medline: 4 12 2023
pubmed: 2 6 2023
entrez: 2 6 2023
Statut: ppublish

Résumé

To evaluate recurrence patterns and survival after recurrence among patients with sinonasal mucosal melanoma (SNMM). This was a multi-institutional retrospective review from seven U.S. institutions of patients with SNMM from 1991 to 2022. Recurrence was categorized as local, regional, distant, or multifocal. Kaplan-Meier tests were used to evaluate disease-free survival (DFS), overall survival (OS), and post-recurrence survival (PRS) reported with standard errors (SE) and log-rank testing used for comparison. Cox-regression was further used, with hazard ratios (HR) and 95% confidence intervals (CI) reported. Among 196 patients with SNMM, there were 146 patients with recurrence (74.5%). Among all patients, 60-month DFS (SE) was 15.5% (2.9%), 60-month OS (SE) was 44.7% (3.7%), mean age ± standard deviation at diagnosis was 69.7 ± 12.5 years, and 54.6% were female. In 26 patients who underwent primary treatment of the neck, 60-month DFS did not differ from no treatment (p > 0.05). Isolated distant recurrence was most common (42.8%), followed by local (28.3%), multifocal (20.7%), and regional recurrence (8.3%). Among patients with regional recurrence in the neck, there was no 60-month PRS benefit for patients undergoing salvage neck dissection or radiation (p > 0.05). Among patients with distant recurrence, only immunotherapy was associated with improved 12-month PRS (HR = 0.32, 95% CI = 0.11-0.92, p = 0.034), and no treatment group was associated with improved 24- or 60-month PRS (p > 0.05). SNMM is associated with a high recurrence rate and poor survival. Primary treatment of the neck was not associated with reduced recurrence, and immunotherapy for treatment of distant recurrence was associated with increased 12-month PRS.

Identifiants

DOI: 10.1002/alr.23204 PMID: 37265013
pubmed: 37265013
doi: 10.1002/alr.23204
doi:

Types de publication

Multicenter Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2156-2164

Informations de copyright

© 2023 ARS-AAOA, LLC.

Références

Low CM, Price DL, Moore EJ, et al. Nodal and distant metastases in sinonasal mucosal melanoma: a population-based analysis. Laryngoscope. 2020;130(3):622-627.
Sun CZ, Li QL, Hu ZD, Jiang YE, Song M, Yang AK. Treatment and prognosis in sinonasal mucosal melanoma: a retrospective analysis of 65 patients from a single cancer center. Head Neck. 2014;36(5):675-681.
Lombardi D, Bottazzoli M, Turri-Zanoni M, et al. Sinonasal mucosal melanoma: a 12-year experience of 58 cases. Head Neck. 2016;38(1):E1737-E1745. Suppl.
Amit M, Tam S, Abdelmeguid AS, et al. Patterns of treatment failure in patients with sinonasal mucosal melanoma. Ann Surg Oncol. 2018;25(6):1723-1729.
Khan MN, Kanumuri VV, Raikundalia MD, et al. Sinonasal melanoma: survival and prognostic implications based on site of involvement. Int Forum Allergy Rhinol. 2014;4(2):151-155.
Ding W, Xie L, Liang J, et al. Pattern and prognostic value of lymph node metastasis in sinonasal mucosal melanoma. Ear Nose Throat J. 2022:1455613221112350. doi:10.1177/01455613221112350. Epub ahead of print.
Amit M, Tam S, Abdelmeguid AS, et al. Approaches to regional lymph node metastasis in patients with head and neck mucosal melanoma. Cancer. 2018;124(3):514-520.
De Virgilio A, Costantino A, Canzano F, et al. Regional disease control in sinonasal mucosal melanoma: systematic review and meta-analysis. Head Neck. 2021;43(2):705-715.
Na'Ara S, Mukherjee A, Billan S, Gil Z. Contemporary multidisciplinary management of sinonasal mucosal melanoma. Onco Targets Ther. 2020;13:2289-2298.
Steininger J, Gellrich FF, Schulz A, Westphal D, Beissert S, Meier F. Systemic therapy of metastatic melanoma: on the road to cure. Cancers (Basel). 2021;13(6):1-28.
Yentz S, Lao CD. Immunotherapy for mucosal melanoma. Ann Transl Med. 2019;7(S3):S118-S118.
Ganti A, Raman A, Shay A, et al. Treatment modalities in sinonasal mucosal melanoma: a national cancer database analysis. Laryngoscope. 2020;130(2):275-282.
Edge SB, Compton CC. The American Joint Committee on Cancer: the 7th Edition of the AJCC Cancer Staging Manual and the Future of TNM. Ann Surg Oncol. 2010;17(6):1471-1474.
Amit M, Tam S, Abdelmeguid AS, et al. Role of adjuvant treatment in sinonasal mucosal melanoma. J Neurol Surg B Skull Base. 2017;78(6):512-518.
Wang T, Huang Y, Lu J, Xiang M. Sinonasal mucosal melanoma: a 10-year experience of 36 cases in China. Ann Transl Med. 2020;8(16):1022-1022.
Johnson BJ, Guo R, Moore EJ, et al. Sinonasal mucosal melanoma: an analysis of treatment-related adverse events and associated factors. Int Forum Allergy Rhinol. 2023;13(6):1037-1041. doi:10.1002/alr.23118. Epub ahead of print
Zebary A, Jangard M, Omholt K, Ragnarsson-Olding B, Hansson J. KIT, NRAS and BRAF mutations in sinonasal mucosal melanoma: a study of 56 cases. Br J Cancer. 2013;109(3):559-564.
Daud AI, Wolchok JD, Robert C, et al. Programmed death-ligand 1 expression and response to the anti-programmed death 1 antibody pembrolizumab in melanoma. J Clin Oncol. 2016;34(34):4102-4109.
Guo R, Jenkins SM, Johnson BJ, Reed K, Kroneman T, Choby G. Sinonasal mucosal melanoma: role of tumor proliferative indices and pathological factors in survival. Laryngoscope. 2022;132(12):2350-2358.

Auteurs

Vivek C Pandrangi (VC)

Department of Otolaryngology-Head and Neck Surgery, Oregon Health & Science University, Portland, Oregon, USA.

Jess C Mace (JC)

Department of Otolaryngology-Head and Neck Surgery, Oregon Health & Science University, Portland, Oregon, USA.

Arash Abiri (A)

Department of Otolaryngology-Head and Neck Surgery, University of California Irvine, Orange, California, USA.

Nithin D Adappa (ND)

Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Daniel M Beswick (DM)

Department of Otolaryngology-Head and Neck Surgery, University of California Los Angeles, Los Angeles, California, USA.
ORCID: 0000-0001-8612-5442

Eugene H Chang (EH)

Department of Otolaryngology-Head and Neck Surgery, University of Arizona, Tucson, Arizona, USA.

Jacob G Eide (JG)

Department of Otolaryngology-Head and Neck Surgery, Henry Ford Health System, Detroit, Michigan, USA.

Nicholas Fung (N)

Department of Otolaryngology-Head and Neck Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Michelle Hong (M)

Department of Otolaryngology-Head and Neck Surgery, University of California Los Angeles, Los Angeles, California, USA.

Brian J Johnson (BJ)

Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota, USA.
ORCID: 0000-0003-4092-8164

Michael A Kohanski (MA)

Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Rijul S Kshirsagar (RS)

Department of Otolaryngology-Head and Neck Surgery, Kaiser Permanente Redwood City Medical Center, Redwood City, California, USA.
ORCID: 0000-0002-3113-2685

Edward C Kuan (EC)

Department of Otolaryngology-Head and Neck Surgery, University of California Irvine, Orange, California, USA.
ORCID: 0000-0003-3475-0718

Christopher H Le (CH)

Department of Otolaryngology-Head and Neck Surgery, University of Arizona, Tucson, Arizona, USA.

Jivianne T Lee (JT)

Department of Otolaryngology-Head and Neck Surgery, University of California Los Angeles, Los Angeles, California, USA.

Seyed A Nabavizadeh (SA)

Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Isaac P Obermeyer (IP)

Department of Otolaryngology-Head and Neck Surgery, University of California Irvine, Orange, California, USA.

James N Palmer (JN)

Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Carlos D Pinheiro-Neto (CD)

Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota, USA.

Timothy L Smith (TL)

Department of Otolaryngology-Head and Neck Surgery, Oregon Health & Science University, Portland, Oregon, USA.
ORCID: 0000-0002-6424-7083

Carl H Snyderman (CH)

Department of Otolaryngology-Head and Neck Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
ORCID: 0000-0002-8920-4522

Jeffrey D Suh (JD)

Department of Otolaryngology-Head and Neck Surgery, University of California Los Angeles, Los Angeles, California, USA.

Eric W Wang (EW)

Department of Otolaryngology-Head and Neck Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
ORCID: 0000-0002-1180-5854

Marilene B Wang (MB)

Department of Otolaryngology-Head and Neck Surgery, University of California Los Angeles, Los Angeles, California, USA.

Garret Choby (G)

Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota, USA.
ORCID: 0000-0002-3745-2727

Mathew Geltzeiler (M)

Department of Otolaryngology-Head and Neck Surgery, Oregon Health & Science University, Portland, Oregon, USA.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Recurrence patterns among patients with...
questionsmedicales.fr › Tissus › Membranes › Muqueuse › Muqueuse respiratoire › Muqueuse nasale › Recurrence patterns among patients with...
questionsmedicales.fr › Maladies oto-rhino-laryngologiques › Tumeurs oto-rhino-laryngologiques › Tumeurs du nez › Tumeurs des sinus de la face › Recurrence patterns among patients with...
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questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Naevus et mélanomes › Mélanome › Recurrence patterns among patients with...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Processus néoplasiques › Récidive tumorale locale › Recurrence patterns among patients with...
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