The Role of Membrane Lipids in the Formation and Function of Caveolae.

Caveolae / chemistry Membrane Lipids / analysis Caveolins / analysis Endocytosis

Journal

Cold Spring Harbor perspectives in biology
ISSN: 1943-0264
Titre abrégé: Cold Spring Harb Perspect Biol
Pays: United States
ID NLM: 101513680

Informations de publication

Date de publication:
01 09 2023
Historique:
pmc-release: 01 09 2024
medline: 4 9 2023
pubmed: 6 6 2023
entrez: 5 6 2023
Statut: epublish

Résumé

Caveolae are plasma membrane invaginations with a distinct lipid composition. Membrane lipids cooperate with the structural components of caveolae to generate a metastable surface domain. Recent studies have provided insights into the structure of essential caveolar components and how lipids are crucial for the formation, dynamics, and disassembly of caveolae. They also suggest new models for how caveolins, major structural components of caveolae, insert into membranes and interact with lipids.

Identifiants

DOI: 10.1101/cshperspect.a041413 PMID: 37277189 PMC: PMC10513159
pubmed: 37277189
pii: cshperspect.a041413
doi: 10.1101/cshperspect.a041413
pmc: PMC10513159
mid: NIHMS1926212
pii:
doi:

Substances chimiques

Membrane Lipids 0
Caveolins 0

Types de publication

Journal Article Review Research Support, Non-U.S. Gov't Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NHLBI NIH HHS
ID : R01 HL144131
Pays : United States

Informations de copyright

Copyright © 2023 Cold Spring Harbor Laboratory Press; all rights reserved.

Auteurs

Anne K Kenworthy (AK)

Center for Membrane and Cell Physiology, University of Virginia, Charlottesville, Virginia 22903, USA akk7hp@virginia.edu R.Parton@imb.uq.edu.au.
Department of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Charlottesville, Virginia 22903, USA.
ORCID: 0000-0001-6567-9059

Bing Han (B)

Center for Membrane and Cell Physiology, University of Virginia, Charlottesville, Virginia 22903, USA.
Department of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Charlottesville, Virginia 22903, USA.

Nicholas Ariotti (N)

Institute for Molecular Bioscience, The University of Queensland, 4072 Brisbane, Australia.

Robert G Parton (RG)

Institute for Molecular Bioscience, The University of Queensland, 4072 Brisbane, Australia akk7hp@virginia.edu R.Parton@imb.uq.edu.au.
Centre for Microscopy and Microanalysis, The University of Queensland, 4072 Brisbane, Australia.

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Classifications MeSH

questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Vésicules cytoplasmiques › Vésicules de transport › Vésicules tapissées › Cavéoles › The Role of Membrane Lipids in the Formation...
questionsmedicales.fr › Lipides › Lipides membranaires › The Role of Membrane Lipids in the Formation...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines du transport vésiculaire › Cavéolines › The Role of Membrane Lipids in the Formation...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Endocytose › The Role of Membrane Lipids in the Formation...