Depressive symptoms and weight change in inpatients with anorexia nervosa: A cross-lagged panel model.


Journal

Journal of psychosomatic research
ISSN: 1879-1360
Titre abrégé: J Psychosom Res
Pays: England
ID NLM: 0376333

Informations de publication

Date de publication:
09 2023
Historique:
received: 14 10 2022
revised: 26 05 2023
accepted: 27 05 2023
medline: 14 8 2023
pubmed: 8 6 2023
entrez: 7 6 2023
Statut: ppublish

Résumé

Anorexia nervosa (AN) is marked by a high rate of comorbid depression, which raises the question whether depressive symptoms may adversely affect treatment outcome. Thus, we examined whether depressive symptoms at admission would predict weight change from admission to discharge in a large sample of inpatients with AN. In addition, we also explored the reverse direction, that is, whether body mass index (BMI) at admission would predict changes in depressive symptoms. A sample of 3011 adolescents and adults with AN (4% male) who received inpatient treatment at four Schoen Clinics was analyzed. Depressive symptoms were measured with the Patient Health Questionnaire-9. BMI significantly increased and depressive symptoms significantly decreased from admission to discharge. BMI and depressive symptoms were unrelated at admission and discharge. Higher BMI at admission predicted smaller decreases in depressive symptoms and higher depressive symptoms at admission predicted larger weight gain. The latter effect, however, was mediated by longer length of stay. Results indicate that depressive symptoms do not adversely affect weight gain during inpatient treatment in persons with AN. Instead, higher BMI at admission is predictive of smaller improvements in depressive symptoms but this effect seems to be negligible in terms of clinical relevance.

Identifiants

pubmed: 37285655
pii: S0022-3999(23)00248-9
doi: 10.1016/j.jpsychores.2023.111391
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

111391

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest None.

Auteurs

Adrian Meule (A)

Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany; Schoen Clinic Roseneck, Prien am Chiemsee, Germany. Electronic address: ameule@med.lmu.de.

David R Kolar (DR)

Department of Psychology, University of Regensburg, Regensburg, Germany.

Thomas Gärtner (T)

Schoen Clinic Bad Arolsen, Bad Arolsen, Germany.

Bernhard Osen (B)

Schoen Clinic Bad Bramstedt, Bad Bramstedt, Germany.

Elisabeth Rauh (E)

Schoen Clinic Bad Staffelstein, Bad Staffelstein, Germany.

Silke Naab (S)

Schoen Clinic Roseneck, Prien am Chiemsee, Germany.

Ulrich Voderholzer (U)

Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany; Schoen Clinic Roseneck, Prien am Chiemsee, Germany; Department of Psychiatry and Psychotherapy, University Hospital of Freiburg, Freiburg, Germany.

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Classifications MeSH