Overtreatment and associated risk factors among multimorbid older patients with diabetes.


Journal

Journal of the American Geriatrics Society
ISSN: 1532-5415
Titre abrégé: J Am Geriatr Soc
Pays: United States
ID NLM: 7503062

Informations de publication

Date de publication:
09 2023
Historique:
revised: 21 04 2023
received: 09 10 2022
accepted: 16 05 2023
medline: 15 9 2023
pubmed: 8 6 2023
entrez: 7 6 2023
Statut: ppublish

Résumé

In multimorbid older patients with type 2 diabetes mellitus (T2DM), the intensity of glucose-lowering medication (GLM) should be focused on attaining a suitable level of glycated hemoglobin (HbA In a secondary analysis of a multicenter study of multimorbid older patients, we evaluated HbA Among the 564 patients with T2DM (median age 78 years, 39% women), mean ± standard deviation HbA In this multicountry study of multimorbid older patients with T2DM, more than one third were overtreated, highlighting the high prevalence of this problem. Careful balancing of benefits and risks in the choice of GLM may improve patient care, especially in the context of comorbidities such as severe renal impairment, and frequent non-GP healthcare contacts.

Sections du résumé

BACKGROUND
In multimorbid older patients with type 2 diabetes mellitus (T2DM), the intensity of glucose-lowering medication (GLM) should be focused on attaining a suitable level of glycated hemoglobin (HbA
METHODS
In a secondary analysis of a multicenter study of multimorbid older patients, we evaluated HbA
RESULTS
Among the 564 patients with T2DM (median age 78 years, 39% women), mean ± standard deviation HbA
CONCLUSIONS
In this multicountry study of multimorbid older patients with T2DM, more than one third were overtreated, highlighting the high prevalence of this problem. Careful balancing of benefits and risks in the choice of GLM may improve patient care, especially in the context of comorbidities such as severe renal impairment, and frequent non-GP healthcare contacts.

Identifiants

pubmed: 37286338
doi: 10.1111/jgs.18465
doi:

Substances chimiques

Metformin 9100L32L2N
Hypoglycemic Agents 0

Types de publication

Multicenter Study Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2893-2901

Subventions

Organisme : European Research Council
ID : 634238
Pays : International
Organisme : Swiss National Science Foundation
ID : SNSF 320030_188549
Pays : Switzerland
Organisme : Swiss National Science Foundation
ID : SNSF 325130_204361/1
Pays : Switzerland

Informations de copyright

© 2023 The Authors. Journal of the American Geriatrics Society published by Wiley Periodicals LLC on behalf of The American Geriatrics Society.

Références

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Auteurs

Oliver Baretella (O)

Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.
Department of General Internal Medicine, Inselspital, Bern University Hospital, Bern, Switzerland.

Heba Alwan (H)

Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.
Graduate School for Health Sciences, University of Bern, Bern, Switzerland.

Martin Feller (M)

Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.
Department of General Internal Medicine, Inselspital, Bern University Hospital, Bern, Switzerland.

Carole E Aubert (CE)

Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.
Department of General Internal Medicine, Inselspital, Bern University Hospital, Bern, Switzerland.

Cinzia Del Giovane (C)

Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.

Dimitrios Papazoglou (D)

Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.
Department of General Internal Medicine, Inselspital, Bern University Hospital, Bern, Switzerland.

Antoine Christiaens (A)

Institut Pierre Louis d'Epidémiologie et de Santé Publique, Sorbonne Université, INSERM, Paris, France.
Clinical Pharmacy research group, Louvain Drug Research Institute (LDRI), Université catholique de Louvain, Brussels, Belgium.

Arend-Jan Meinders (AJ)

Department of Internal Medicine, St Antonius Hospital, Nieuwegein, the Netherlands.

Stephen Byrne (S)

School of Pharmacy, University College Cork - National University of Ireland, Cork, Republic of Ireland.

Patricia M Kearney (PM)

School of Public Health, University College Cork, Cork, Republic of Ireland.
Department of Medicine Cork, University College Cork - National University of Ireland, Cork, Republic of Ireland.

Denis O'Mahony (D)

Department of Medicine Cork, University College Cork - National University of Ireland, Cork, Republic of Ireland.
Department of Geriatric Medicine Cork, Cork University Hospital Group, Cork, Republic of Ireland.

Wilma Knol (W)

Department of Geriatrics and Expertise Centre Pharmacotherapy in Old Persons (EPHOR), University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.

Benoît Boland (B)

Clinical Pharmacy research group, Louvain Drug Research Institute (LDRI), Université catholique de Louvain, Brussels, Belgium.
Department of Geriatric Medicine, Cliniques universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium.

Baris Gencer (B)

Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.
Service de cardiologie, Hôpitaux Universitaires de Genève (HUG), Geneva, Switzerland.

Drahomir Aujesky (D)

Department of General Internal Medicine, Inselspital, Bern University Hospital, Bern, Switzerland.

Nicolas Rodondi (N)

Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.
Department of General Internal Medicine, Inselspital, Bern University Hospital, Bern, Switzerland.

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