Attachment representations in 7-year-old children at familial high risk of schizophrenia or bipolar disorder: Associations with mental disorders and daily functioning: The Danish High Risk and Resilience Study, VIA 7-A population-based cohort study.

Attachment childhood and adolescence familial high risk mental disorders psychosis

Journal

Scandinavian journal of psychology
ISSN: 1467-9450
Titre abrégé: Scand J Psychol
Pays: England
ID NLM: 0404510

Informations de publication

Date de publication:
Dec 2023
Historique:
revised: 23 05 2023
received: 17 01 2023
accepted: 24 05 2023
medline: 20 11 2023
pubmed: 13 6 2023
entrez: 13 6 2023
Statut: ppublish

Résumé

Attachment quality may affect psychological functioning. However, evidence on attachment representations and their correlates in children born to parents with schizophrenia and bipolar disorder is sparse. We compared attachment representations in a Danish sample of 482 children aged 7 years at familial high risk of schizophrenia, bipolar disorder, and population-based controls and examined associations between attachment and mental disorders and daily functioning. Attachment representations were examined with the Story Stem Assessment Profile (SSAP). Mental disorders were ascertained in diagnostic interviews. Daily functioning was assessed with the Children's Global Assessment Scale. We found no between-group differences in attachment. Higher levels of secure attachment were associated with decreased risk of concurrent mental disorders in the schizophrenia high-risk group. Higher levels of insecure and disorganized attachment were associated with increased risk of mental disorders across the cohort. Higher levels of secure and insecure attachment were associated with better and poorer daily functioning, respectively. In the current study, results regarding defensive avoidance could not be reported due to methodological limitations. Familial high risk of schizophrenia (FHR-SZ) or bipolar disorder is not associated with less secure or more insecure attachment at age 7. Insecure and disorganized attachment representations index risk of mental disorders and poorer functioning. Secure attachment may be a protective factor against mental disorders in children at FHR-SZ. Validation of the SSAP is needed.

Sections du résumé

BACKGROUND BACKGROUND
Attachment quality may affect psychological functioning. However, evidence on attachment representations and their correlates in children born to parents with schizophrenia and bipolar disorder is sparse.
METHODS METHODS
We compared attachment representations in a Danish sample of 482 children aged 7 years at familial high risk of schizophrenia, bipolar disorder, and population-based controls and examined associations between attachment and mental disorders and daily functioning. Attachment representations were examined with the Story Stem Assessment Profile (SSAP). Mental disorders were ascertained in diagnostic interviews. Daily functioning was assessed with the Children's Global Assessment Scale.
RESULTS RESULTS
We found no between-group differences in attachment. Higher levels of secure attachment were associated with decreased risk of concurrent mental disorders in the schizophrenia high-risk group. Higher levels of insecure and disorganized attachment were associated with increased risk of mental disorders across the cohort. Higher levels of secure and insecure attachment were associated with better and poorer daily functioning, respectively. In the current study, results regarding defensive avoidance could not be reported due to methodological limitations.
CONCLUSION CONCLUSIONS
Familial high risk of schizophrenia (FHR-SZ) or bipolar disorder is not associated with less secure or more insecure attachment at age 7. Insecure and disorganized attachment representations index risk of mental disorders and poorer functioning. Secure attachment may be a protective factor against mental disorders in children at FHR-SZ. Validation of the SSAP is needed.

Identifiants

pubmed: 37309265
doi: 10.1111/sjop.12941
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

776-783

Subventions

Organisme : Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH)
Organisme : Beatrice Surovell Haskell Fund for Child Mental Health Research of Copenhagen
Organisme : Capital Region of Denmark
Organisme : Mental Health Services of the Capital Region of Denmark
Organisme : TRYG Foundation

Informations de copyright

© 2023 Scandinavian Psychological Associations and John Wiley & Sons Ltd.

Références

Ainsworth, M.D.S., Blehar, M.C., Waters, E. & Wall, S. (1978). Patterns of attachment. A Psychological Study of the Strange Situation. New York: Psychology Press.
Anke, T.M.S., Slinning, K., Moe, V., Brunborg, C., Siqveland, T.S. & Skjelstad, D.V. (2020). Bipolar offspring and mothers: Interactional challenges at infant age 3 and 12 months-a developmental pathway to enhanced risk? International Journal of Bipolar Disorders, 8, 27.
Atkinson, L., Paglia, A., Coolbear, J., Niccols, A., Parker, K.C. & Guger, S. (2000). Attachment security: A meta-analysis of maternal mental health correlates. Clinical Psychology Review, 20, 1019-1040.
Barnes, J. & Theule, J. (2019). Maternal depression and infant attachment security: A meta-analysis. Infant Mental Health Journal, 40, 817-834.
Belsky, J. & Cassidy, J. (1994). Attachment: Theory and evidence. In M. Rutter & D. Hay (Eds.), Development through life: A handbook for clinicians (pp. 373-402). Oxford: Blackwell.
Benoit, D. (2004). Infant-parent attachment: Definition, types, antecedents, measurement and outcome. Paediatrics & Child Health, 9, 541-545.
Bowlby, J. (1969). Attachment and loss: Attachment: Volume 1, 1st edition. New York: Basic Books.
Bretherton, I., Ridgeway, D. & Cassidy, J. (1990). Assessing internal working models of the attachment relationship: An attachment story completion task for 3-year-olds. In M.T. Greenberg, D. Cicchetti & E.M. Cummings (Eds.), Attachment in the preschool years. Theory, research, and intervention (pp. 273-308). Chicago: University of Chicago Press.
Brumariu, L.E. & Kerns, K.A. (2010). Parent-child attachment and internalizing symptoms in childhood and adolescence: A review of empirical findings and future directions. Development and Psychopathology, 22, 177-203.
Carlson, E.A. (1998). A prospective longitudinal study of attachment disorganization/disorientation. Child Development, 69, 1107-1128.
Carr, S.C., Hardy, A. & Fornells-Ambrojo, M. (2018). Relationship between attachment style and symptom severity across the psychosis spectrum: A meta-analysis. Clinical Psychology Review, 59, 145-158.
Carter, A.S., Garrity-Rokous, F.E., Chazan-Cohen, R., Little, C. & Briggs-Gowan, M.J. (2001). Maternal depression and comorbidity: Predicting early parenting, attachment security, and toddler social-emotional problems and competencies. Journal of the American Academy of Child and Adolescent Psychiatry, 40, 18-26.
Cassidy, J. (1994). Emotion regulation: Influences of attachment relationships. Monographs of the Society for Research in Child Development, 59, 228-249.
Cassidy, J. (2008). The nature of the Child's ties. In J. Cassidy & P.R. Shaver (Eds.), Handbook of attachment: Theory, research, and clinical applications (pp. 3-22). New York: The Guilford Press.
D'angelo, E.J. (1986). Security of attachment in infants with schizophrenic, depressed, and unaffected mothers. The Journal of Genetic Psychology, 147, 421-422.
Davidsen, K.A., Harder, S., MacBeth, A., Lundy, J.-M. & Gumley, A. (2015). Mother-infant interaction in schizophrenia: Transmitting risk or resilience? A systematic review of the literature. Social Psychiatry and Psychiatric Epidemiology, 50, 1785-1798.
Davidsen, K.A., Munk-Laursen, T., Foli-Andersen, P., Ranning, A., Harder, S., Nordentoft, M. et al. (2021). Mental and pediatric disorders among children 0-6 years of parents with severe mental illness. Acta Psychiatrica Scandinavica, 145, 244-254.
DeKlyen, M. & Greenberg, M.T. (2008). Attachment and psychopathology in childhood. In J. Cassidy & P.R. Shaver (Eds.), Handbook of attachment. Theory, research, and clinical applications (2nd ed., pp.  637-665). New York: The Guilford Press.
Delgado, E., Serna, C., Martínez, I. & Cruise, E. (2022). Parental attachment and peer relationships in adolescence: A systematic review. International Journal of Environmental Research and Public Health, 19, 1064.
DeMulder, E.K. & Radke-Yarrow, M. (1991). Attachment with affectively ill and well mothers: Concurrent behavioral correlates. Development and Psychopathology, 3, 227-242.
Doucette, S., Horrocks, J., Grof, P., Keown-Stoneman, C. & Duffy, A. (2013). Attachment and temperament profiles among the offspring of a parent with bipolar disorder. Journal of Affective Disorders, 150, 522-526.
Ellersgaard, D.V., Plessen, K.J., Jepsen, J.R., Spang, K.S., Hemager, N., Burton, B.K. et al. (2018). Psychopathology in 7-year-old children with familial high risk of developing schizophrenia spectrum psychosis or bipolar disorder: The Danish High Risk and Resilience Study-VIA 7, a population-based cohort study. World Psychiatry, 17, 210-219.
Erkan, M., Gencoglan, S., Akguc, L., Ozatalay, E. & Fettahoglu, E.C. (2015). Attachment styles and psychopathology among adolescent children of parents with bipolar disorder. Medical Science Monitor: International Medical Journal of Experimental and Clinical Research, 21, 1083-1088.
Fearon, R.P., Bakermans-Kranenburg, M.J., van Ijzendoorn, M.H., Lapsley, A.-M. & Roisman, G.I. (2010). The significance of insecure attachment and disorganization in the development of children's externalizing behavior: A meta-analytic study. Child Development, 81, 435-456.
Granot, D. & Mayseless, O. (2001). Attachment security and adjustment to school in middle childhood. International Journal of Behavioral Development, 25, 530-541.
Granqvist, P., Sroufe, L.A., Dozier, M., Hesse, E., Steele, M., van Ijzendoorn, M. et al. (2017). Disorganized attachment in infancy: A review of the phenomenon and its implications for clinicians and policy-makers. Attachment & Human Development, 19, 534-558.
Green, J. & Goldwyn, R. (2002). Annotation: Attachment disorganisation and psychopathology: New findings in attachment research and their potential implications for developmental psychopathology in childhood. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 43, 835-846.
Gregersen, M., Søndergaard, A., Brandt, J.M., Ellersgaard, D., Rohd, S.B., Hjorthøj, C. et al. (2022). Mental disorders in preadolescent children at familial high-risk of schizophrenia or bipolar disorder - A four-year follow-up study: The Danish High Risk and Resilience Study, VIA 11: The Danish High Risk and Resilience Study, VIA 11. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 63, 1046-1056.
Groh, A.M., Fearon, R.P., Bakermans-Kranenburg, M.J., van Ijzendoorn, M.H., Steele, R.D. & Roisman, G.I. (2014). The significance of attachment security for children's social competence with peers: A meta-analytic study. Attachment & Human Development, 16, 103-136.
Groh, A.M., Roisman, G.I., van Ijzendoorn, M.H., Bakermans-Kranenburg, M.J. & Fearon, R.P. (2012). The significance of insecure and disorganized attachment for children's internalizing symptoms: A meta-analytic study. Child Development, 83, 591-610.
Gumley, A.I., Schwannauer, M., Macbeth, A., Fisher, R., Clark, S., Rattrie, L. et al. (2014). Insight, duration of untreated psychosis and attachment in first-episode psychosis: Prospective study of psychiatric recovery over 12-month follow-up. The British Journal of Psychiatry: the Journal of Mental Science, 205, 60-67.
Herstell, S., Betz, L.T., Penzel, N., Chechelnizki, R., Filihagh, L., Antonucci, L. et al. (2021). Insecure attachment as a transdiagnostic risk factor for major psychiatric conditions: A meta-analysis in bipolar disorder, depression and schizophrenia spectrum disorder. Journal of Psychiatric Research, 144, 190-201.
Hillman, S. (2011). The standardisation and validation of the Story Stem Assessment Profile (SSAP), a clinical narrative-based assessment for children, Unpublished PhD-Thesis. London: University of London.
Hillman, S., Cross, R. & Anderson, K. (2020). Exploring attachment and internal representations in looked-after children. Frontiers in Psychology, 11, 464.
Hillman, S. & Hodges, J. (2017). SSAP tables, Unpublished. London: Anna Freud National Centre for Children and Families.
Hillman, S., Hodges, J., Steele, M., Cirasola, A., Asquith, K. & Kaniuk, J. (2020). Assessing changes in the internal worlds of early- and late-adopted children using the Story Stem Assessment Profile (SSAP). Adoption & Fostering, 44, 377-396.
Hipwell, A.E., Goossens, F.A., Melhuish, E.C. & Kumar, R. (2000). Severe maternal psychopathology and infant-mother attachment. Development and Psychopathology, 12, 157-175.
Hodges, J., Hillman, S., Stufkens, M. & Steele, M. (2015). Story Stem Assessment Profile (SSAP), Unpublished Coding Manual. London: Anna Freud National Centre for Children and Families.
Hodges, J., Steele, M., Hillman, S. & Henderson, K. (2014). Mental representations and defenses in severely maltreated children: A story stem battery and rating system for clinical assessment and research applications. In R.N. Emde, D.P. Wolf & D. Oppenheim (Eds.), Revealing the inner worlds of young children; the MacArthur story stem battery and parent-child narratives (pp. 240-267). Oxford: Oxford University Press.
Jewell, T., Gardner, T., Susi, K., Watchorn, K., Coopey, E., Simic, M. et al. (2019). Attachment measures in middle childhood and adolescence: A systematic review of measurement properties. Clinical Psychology Review, 68, 71-82.
Kaufman, J., Birmaher, B., Brent, D., Rao, U., Flynn, C., Moreci, P. et al. (1997). Schedule for affective disorders and schizophrenia for school-age children-present and lifetime version (K-SADS-PL): Initial reliability and validity data. Journal of the American Academy of Child and Adolescent Psychiatry, 36, 980-988.
Madigan, S., Atkinson, L., Laurin, K. & Benoit, D. (2013). Attachment and internalizing behavior in early childhood: A meta-analysis. Developmental Psychology, 49, 672-689.
Main, M. & Solomon, J. (1990). Procedures for identifying infants as disorganized/disoriented during the Ainsworth strange situation. In M.T. Greenberg, D. Cicchetti & E. Mark Cummings (Eds.), Attachment in the preschool years. Theory, research, and intervention (pp. 121-160). Chicago: University of Chicago Press.
McNeil, T.F. & Kaij, L. (1987). Swedish high-risk study: Sample characteristics at age 6. Schizophrenia Bulletin, 13, 373-381.
Mors, O., Perto, G.P. & Mortensen, P.B. (2011). The Danish psychiatric central research register. Scandinavian Journal of Public Health, 39, 54-57.
Murphy, R., Goodall, K. & Woodrow, A. (2020). The relationship between attachment insecurity and experiences on the paranoia continuum: A meta-analysis. The British Journal of Clinical Psychology, 59, 290-318.
Näslund, B., Persson-Blennow, I., McNeil, T., Kaij, L. & Malmquist-Larsson, A. (1984). Offspring of women with nonorganic psychosis: Infant attachment to the mother at one year of age. Acta Psychiatrica Scandinavica, 69, 231-241.
O'Neill, M.C., Badovinac, S., Riddell, R.P., Bureau, J.-F., Rumeo, C. & Costa, S. (2021). The longitudinal and concurrent relationship between caregiver sensitivity and preschool attachment: A systematic review and meta-analysis. PLoS One, 16, e0245061.
Pallini, S., Baiocco, R., Schneider, B.H., Madigan, S. & Atkinson, L. (2014). Early child-parent attachment and peer relations: A meta-analysis of recent research. Journal of Family Psychology, 28, 118-123.
Pallini, S., Morelli, M., Chirumbolo, A., Baiocco, R., Laghi, F. & Eisenberg, N. (2019). Attachment and attention problems: A meta-analysis. Clinical Psychology Review, 74, 101772.
Pedersen, C.B., Gøtzsche, H., Møller, J.O. & Mortensen, P.B. (2006). The Danish Civil Registration System. A cohort of eight million persons. Danish Medical Bulletin, 53, 441-449.
Persson-Blennow, I., Binett, B. & McNeil, T.F. (1988). Offspring of women with nonorganic psychosis: Antecedents of anxious attachment to the mother at one year of age. Acta Psychiatrica Scandinavica, 78, 66-71.
Psouni, E., Di Folco, S. & Zavattini, G.C. (2015). Scripted secure base knowledge and its relation to perceived social acceptance and competence in early middle childhood. Scandinavian Journal of Psychology, 56, 341-348.
Radke-Yarrow, M., Cummings, E.M., Kuczynski, L. & Chapman, M. (1985). Patterns of attachment in two- and three-year-olds in normal families and families with parental depression. Child Development, 56, 884-893.
Radke-Yarrow, M., McCann, K., DeMulder, E., Belmont, B., Martinez, P. & Richardson, D.T. (1995). Attachment in the context of high-risk conditions. Development and Psychopathology, 7, 247-265.
Rasic, D., Hajek, T., Alda, M. & Uher, R. (2014). Risk of mental illness in offspring of parents with schizophrenia, bipolar disorder, and major depressive disorder: A meta-analysis of family high-risk studies. Schizophrenia Bulletin, 40, 28-38.
Righetti-Veltema, M., Bousquet, A. & Manzano, J. (2003). Impact of postpartum depressive symptoms on mother and her 18-month-old infant. European Child & Adolescent Psychiatry, 12, 75-83.
Román, M., Palacios, J., Moreno, C. & López, A. (2012). Attachment representations in internationally adopted children. Attachment & Human Development, 14, 585-600.
Sameroff, A.J., Seifer, R. & Zax, M. (1982). Early development of children at risk for emotional disorder. Monographs of the Society for Research in Child Development, 47, 1-82.
Shaffer, D., Gould, M.S., Brasic, J., Ambrosini, P., Fisher, P., Bird, H. et al. (1983). A children's global assessment scale (CGAS). Archives of General Psychiatry, 40, 1228-1231.
Shmueli-Goetz, Y., Target, M., Fonagy, P. & Datta, A. (2008). The child attachment interview: A psychometric study of reliability and discriminant validity. Developmental Psychology, 44, 939-956.
Smith-Nielsen, J., Tharner, A., Steele, H., Cordes, K., Mehlhase, H. & Vaever, M.S. (2016). Postpartum depression and infant-mother attachment security at one year: The impact of co-morbid maternal personality disorders. Infant Behavior & Development, 44, 148-158.
Sroufe, L.A. (2005). Attachment and development: A prospective, longitudinal study from birth to adulthood. Attachment & Human Development, 7, 349-367.
Sroufe, L.A., Egeland, B., Carlson, E.A. & Collins, W.A. (2005). The development of the person. In The Minnesota study of risk and adaptation from birth to adulthood (Vol. 1). New York: The Guilford Press.
Tharner, A., Luijk, M.P.C.M., van IJzendoorn, M.H., Bakermans-Kranenburg, M.J., Jaddoe, V.W.V., Hofman, A. et al. (2012). Maternal lifetime history of depression and depressive symptoms in the prenatal and early postnatal period do not predict infant-mother attachment quality in a large, population-based Dutch cohort study. Attachment & Human Development, 14, 63-81.
Thorup, A.A.E., Jepsen, J.R., Ellersgaard, D.V., Burton, B.K., Christiani, C.J., Hemager, N. et al. (2015). The Danish high risk and resilience study-VIA 7: A cohort study of 520 7-year-old children born of parents diagnosed with either schizophrenia, bipolar disorder or neither of these two mental disorders. BMC Psychiatry, 15, 233.
van Ijzendoorn, M.H., Schuengel, C. & Bakermans-Kranenburg, M.J. (1999). Disorganized attachment in early childhood: Meta-analysis of precursors, concomitants, and sequelae. Development and Psychopathology, 11, 225-249.
Van Ryzin, M.J., Carlson, E.A. & Sroufe, L.A. (2011). Attachment discontinuity in a high-risk sample. Attachment & Human Development, 13, 381-401.
Wan, M.W., Salmon, M.P., Riordan, D.M., Appleby, L., Webb, R. & Abel, K.M. (2007). What predicts poor mother-infant interaction in schizophrenia? Psychological Medicine, 37, 537-546.
Zahn-Waxler, C., Chapman, M. & Cummings, E.M. (1984). Cognitive and social development in infants and toddlers with a bipolar parent. Child Psychiatry and Human Development, 15, 75-85.

Auteurs

Maja Gregersen (M)

CORE - Copenhagen Research Centre for Mental Health, Mental Health Services in the Capital Region of Denmark, Mental Health Centre Copenhagen, Copenhagen, Denmark.
The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.

Ditte Ellersgaard (D)

CORE - Copenhagen Research Centre for Mental Health, Mental Health Services in the Capital Region of Denmark, Mental Health Centre Copenhagen, Copenhagen, Denmark.

Anne Søndergaard (A)

CORE - Copenhagen Research Centre for Mental Health, Mental Health Services in the Capital Region of Denmark, Mental Health Centre Copenhagen, Copenhagen, Denmark.
The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.

Camilla Christiani (C)

CORE - Copenhagen Research Centre for Mental Health, Mental Health Services in the Capital Region of Denmark, Mental Health Centre Copenhagen, Copenhagen, Denmark.
The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.

Nicoline Hemager (N)

CORE - Copenhagen Research Centre for Mental Health, Mental Health Services in the Capital Region of Denmark, Mental Health Centre Copenhagen, Copenhagen, Denmark.
The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.
Mental Health Services in the Capital Region of Denmark, Child and Adolescent Mental Health Centre, Copenhagen, Denmark.

Katrine Søborg Spang (KS)

Mental Health Services in the Capital Region of Denmark, Child and Adolescent Mental Health Centre, Copenhagen, Denmark.

Birgitte Klee Burton (BK)

Mental Health Services in the Capital Region of Denmark, Child and Adolescent Mental Health Centre, Copenhagen, Denmark.
University of Copenhagen - Faculty of Health and Medical Sciences, Copenhagen, Denmark.
Department of Child and Adolescent Psychiatry, Copenhagen University Hospital, Psychiatry Region Zealand, Roskilde, Denmark.

Md Jamal Uddin (MJ)

CORE - Copenhagen Research Centre for Mental Health, Mental Health Services in the Capital Region of Denmark, Mental Health Centre Copenhagen, Copenhagen, Denmark.
The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.

Jessica Ohland (J)

CORE - Copenhagen Research Centre for Mental Health, Mental Health Services in the Capital Region of Denmark, Mental Health Centre Copenhagen, Copenhagen, Denmark.
The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.

Ditte Gantriis (D)

The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.
Psychosis Research Unit, Aarhus University Hospital, Aarhus, Denmark.

Aja Greve (A)

The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.
Psychosis Research Unit, Aarhus University Hospital, Aarhus, Denmark.

Carsten Hjorthøj (C)

CORE - Copenhagen Research Centre for Mental Health, Mental Health Services in the Capital Region of Denmark, Mental Health Centre Copenhagen, Copenhagen, Denmark.
The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.
Department of Public Health, Section of Epidemiology, University of Copenhagen, Copenhagen, Denmark.

Ole Mors (O)

The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.
Psychosis Research Unit, Aarhus University Hospital, Aarhus, Denmark.
Department of Clinical Medicine, Faculty of Health and Medical Sciences, Aarhus University, Aarhus, Denmark.

Kerstin Jessica Plessen (KJ)

Division of Child and Adolescent Psychiatry, Department of Psychiatry, University Hospital, Lausanne, Switzerland.

Merete Nordentoft (M)

CORE - Copenhagen Research Centre for Mental Health, Mental Health Services in the Capital Region of Denmark, Mental Health Centre Copenhagen, Copenhagen, Denmark.
The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.
University of Copenhagen - Faculty of Health and Medical Sciences, Copenhagen, Denmark.

Lars Clemmensen (L)

CORE - Copenhagen Research Centre for Mental Health, Mental Health Services in the Capital Region of Denmark, Mental Health Centre Copenhagen, Copenhagen, Denmark.

Jens Richardt Møllegaard Jepsen (JRM)

CORE - Copenhagen Research Centre for Mental Health, Mental Health Services in the Capital Region of Denmark, Mental Health Centre Copenhagen, Copenhagen, Denmark.
The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.
Mental Health Services in the Capital Region of Denmark, Child and Adolescent Mental Health Centre, Copenhagen, Denmark.
Center for Neuropsychiatric Schizophrenia Research and Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research, Mental Health Services in the Capital Region of Denmark, Copenhagen, Denmark.

Anne Amalie Elgaard Thorup (AAE)

The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.
Mental Health Services in the Capital Region of Denmark, Child and Adolescent Mental Health Centre, Copenhagen, Denmark.
University of Copenhagen - Faculty of Health and Medical Sciences, Copenhagen, Denmark.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH