An Atypical F-Actin Capping Protein Modulates Cytoskeleton Behaviors Crucial for Trichomonas vaginalis Colonization.

Trichomonas vaginalis / metabolism Actins / metabolism Cytoskeleton / metabolism Actin Cytoskeleton / metabolism Actin Capping Proteins / metabolism
Trichomonas vaginalis actin capping protein actin cytoskeleton colonization cytoadherence

Journal

Microbiology spectrum
ISSN: 2165-0497
Titre abrégé: Microbiol Spectr
Pays: United States
ID NLM: 101634614

Informations de publication

Date de publication:
17 08 2023
Historique:
medline: 21 8 2023
pubmed: 13 6 2023
entrez: 13 6 2023
Statut: ppublish

Résumé

Cytoadherence and migration are crucial for pathogens to establish colonization in the host. In contrast to a nonadherent isolate of Trichomonas vaginalis, an adherent one expresses more actin-related machinery proteins with more active flagellate-amoeboid morphogenesis, amoeba migration, and cytoadherence, activities that were abrogated by an actin assembly blocker. By immunoprecipitation coupled with label-free quantitative proteomics, an F-actin capping protein (T. vaginalis F-actin capping protein subunit α [

Identifiants

DOI: 10.1128/spectrum.00596-23 PMID: 37310229 PMC: PMC10434240
pubmed: 37310229
doi: 10.1128/spectrum.00596-23
pmc: PMC10434240
doi:

Substances chimiques

Actins 0
Actin Capping Proteins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0059623

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

Références

J Cell Sci. 2018 Apr 23;131(8):
pubmed: 29535210
EMBO J. 1985 Nov;4(11):2815-8
pubmed: 4065095
Methods Mol Biol. 2009;571:401-15
pubmed: 19763982
Infect Immun. 2009 Jul;77(7):2703-11
pubmed: 19380472
Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):E6610-E6619
pubmed: 27791032
FEBS Lett. 2005 Jan 3;579(1):48-52
pubmed: 15620689
Curr Biol. 2003 Sep 2;13(17):1531-7
pubmed: 12956956
EMBO J. 2004 Aug 4;23(15):3010-9
pubmed: 15282541
J Biol Chem. 2006 Nov 24;281(47):36347-59
pubmed: 16987810
Trends Biochem Sci. 2004 Dec;29(12):674-81
pubmed: 15544954
J Cell Biol. 2010 Jan 25;188(2):287-97
pubmed: 20100912
Sci Rep. 2020 Jan 27;10(1):1275
pubmed: 31988345
Science. 2007 Jan 12;315(5809):207-12
pubmed: 17218520
mBio. 2021 Feb 9;12(1):
pubmed: 33563826
BMC Cell Biol. 2009 Nov 08;10:81
pubmed: 19895707
J Cell Biol. 2020 Nov 2;219(11):
pubmed: 32960946
Cell Microbiol. 2017 Jun;19(6):
pubmed: 28054438
Nat Struct Mol Biol. 2010 Apr;17(4):497-503
pubmed: 20357771
Proc Natl Acad Sci U S A. 1998 May 26;95(11):6181-6
pubmed: 9600938
Cell Adh Migr. 2007 Jan-Mar;1(1):13-8
pubmed: 19262093
Microb Pathog. 1996 Jun;20(6):335-49
pubmed: 8831829
Eur J Clin Invest. 2008 Oct;38 Suppl 2:29-38
pubmed: 18826479
J Biol Chem. 1976 Dec 10;251(23):7474-9
pubmed: 1002696
Microb Pathog. 2004 May;36(5):263-71
pubmed: 15043861
J Clin Microbiol. 2013 Aug;51(8):2483-90
pubmed: 23616456
Nat Rev Mol Cell Biol. 2014 Oct;15(10):677-89
pubmed: 25207437
Cell Microbiol. 2013 Oct;15(10):1707-21
pubmed: 23530917
Proc Natl Acad Sci U S A. 2019 Oct 8;116(41):20418-20427
pubmed: 31548388
Mol Microbiol. 2003 Mar;47(5):1207-24
pubmed: 12603729
Exp Cell Res. 1961;Suppl 8:32-46
pubmed: 13785585
Cell Microbiol. 2005 Feb;7(2):245-58
pubmed: 15659068
J Protozool. 1971 May;18(2):337-43
pubmed: 5091282
mBio. 2019 May 14;10(3):
pubmed: 31088924
Respir Res. 2017 Apr 8;18(1):54
pubmed: 28390425
J Protozool. 1986 Nov;33(4):467-72
pubmed: 3795140
Trends Cell Biol. 2021 Mar;31(3):211-223
pubmed: 33376040
PLoS Negl Trop Dis. 2023 Jan 3;17(1):e0011016
pubmed: 36595499
FEBS Lett. 2001 May 4;496(1):44-8
pubmed: 11343704
Parasite Immunol. 2019 Aug;41(8):e12631
pubmed: 31077592
Nat Rev Mol Cell Biol. 2010 Sep;11(9):633-43
pubmed: 20729930
Cold Spring Harb Perspect Biol. 2017 Jul 5;9(7):
pubmed: 28679638
PLoS Pathog. 2015 Dec 18;11(12):e1005294
pubmed: 26684303
Curr Protoc Protein Sci. 2018 Aug;93(1):e61
pubmed: 30011131
Nat Cell Biol. 2001 Mar;3(3):259-66
pubmed: 11231575
Biomed Res Int. 2013;2013:561979
pubmed: 23509742
Science. 2009 Nov 27;326(5957):1208-12
pubmed: 19965462
Mol Microbiol. 1993 Jan;7(2):299-309
pubmed: 8446032
Nat Commun. 2021 Sep 9;12(1):5329
pubmed: 34504078
Cell Mol Life Sci. 2000 Jan 20;57(1):41-64
pubmed: 10949580
Methods Mol Biol. 2013;1046:145-70
pubmed: 23868587
Proc Natl Acad Sci U S A. 1988 Nov;85(21):8042-6
pubmed: 2973059
Infect Immun. 2012 Nov;80(11):3900-11
pubmed: 22927047
Biophys Rev. 2021 Sep 4;13(5):679-695
pubmed: 34777614
J Biol Chem. 1990 Oct 15;265(29):17980-7
pubmed: 2211676
J Biol Chem. 2014 Oct 17;289(42):29334-49
pubmed: 25183012
Mol Microbiol. 1995 Jul;17(1):69-83
pubmed: 7476210
J Cell Biol. 2004 Feb 16;164(4):567-80
pubmed: 14769858
Cell Mol Life Sci. 2022 Feb 8;79(2):125
pubmed: 35132495
Am J Respir Cell Mol Biol. 1993 Jun;8(6):582-91
pubmed: 8323743
Parasitol Res. 2017 Dec;116(12):3275-3284
pubmed: 29026991
Mol Cell Biol. 2005 May;25(9):3519-34
pubmed: 15831458
Cell Mol Neurobiol. 1999 Dec;19(6):733-44
pubmed: 10456234

Auteurs

Kai-Hsuan Wang (KH)

Department of Tropical Medicine and Parasitology, College of Medicine, National Taiwan University, Taipei, Taiwan.

Jing-Yang Chang (JY)

Department of Tropical Medicine and Parasitology, College of Medicine, National Taiwan University, Taipei, Taiwan.

Fu-An Li (FA)

The Proteomic Core, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.

Kuan-Yi Wu (KY)

Department of Tropical Medicine and Parasitology, College of Medicine, National Taiwan University, Taipei, Taiwan.

Shu-Hao Hsu (SH)

Department of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei, Taiwan.

Yen-Ju Chen (YJ)

Department of Tropical Medicine and Parasitology, College of Medicine, National Taiwan University, Taipei, Taiwan.

Tse-Ling Chu (TL)

Taipei First Girls High School, Taipei, Taiwan.

Jessica Lin (J)

Taipei First Girls High School, Taipei, Taiwan.

Hong-Ming Hsu (HM)

Department of Tropical Medicine and Parasitology, College of Medicine, National Taiwan University, Taipei, Taiwan.
ORCID: 0000-0002-7579-5106

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Parabasalidea › Trichomonadida › Trichomonas › Trichomonas vaginalis › An Atypical F-Actin Capping Protein Modulates...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines du cytosquelette › Protéines des microfilaments › Actines › An Atypical F-Actin Capping Protein Modulates...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Cytosquelette › An Atypical F-Actin Capping Protein Modulates...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Cytosquelette › Cytosquelette d'actine › An Atypical F-Actin Capping Protein Modulates...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines du cytosquelette › Protéines des microfilaments › Protéines de coiffe de l'actine › An Atypical F-Actin Capping Protein Modulates...