Biology and function of pericytes in the vascular microcirculation.
inflammation
pericytes
pluripotency
vascular microcirculatory
Journal
Animal models and experimental medicine
ISSN: 2576-2095
Titre abrégé: Animal Model Exp Med
Pays: United States
ID NLM: 101726292
Informations de publication
Date de publication:
08 2023
08 2023
Historique:
received:
12
12
2022
accepted:
16
05
2023
medline:
11
9
2023
pubmed:
15
6
2023
entrez:
15
6
2023
Statut:
ppublish
Résumé
Pericytes are the main cellular components of tiny arteries and capillaries. Studies have found that pericytes can undergo morphological contraction or relaxation under stimulation by cytokines, thus affecting the contraction and relaxation of microvessels and playing an essential role in regulating vascular microcirculation. Moreover, due to the characteristics of stem cells, pericytes can differentiate into a variety of inflammatory cell phenotypes, which then affect the immune function. Additionally, pericytes can also participate in angiogenesis and wound healing by interacting with endothelial cells in vascular microcirculation disorders. Here we review the origin, biological phenotype and function of pericytes, and discuss the potential mechanisms of pericytes in vascular microcirculation disorders, especially in pulmonary hypertension, so as to provide a sound basis and direction for the prevention and treatment of vascular microcirculation diseases.
Identifiants
pubmed: 37317664
doi: 10.1002/ame2.12334
pmc: PMC10486323
doi:
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
337-345Informations de copyright
© 2023 The Authors. Animal Models and Experimental Medicine published by John Wiley & Sons Australia, Ltd on behalf of The Chinese Association for Laboratory Animal Sciences.
Références
Front Cell Neurosci. 2019 Nov 22;13:519
pubmed: 31824267
J Clin Invest. 2022 May 16;132(10):
pubmed: 35349488
Microvasc Res. 2022 Jul;142:104349
pubmed: 35240123
Elife. 2017 Nov 09;6:
pubmed: 29120327
Sci Adv. 2023 Feb 15;9(7):eabq1141
pubmed: 36791205
Cell Rep. 2017 May 30;19(9):1902-1916
pubmed: 28564607
J Neuroinflammation. 2015 Jul 08;12:131
pubmed: 26152369
Int Arch Allergy Immunol. 2014;164(3):178-88
pubmed: 25034005
Cell Discov. 2018 Jan 16;4:3
pubmed: 29423271
J Vasc Res. 2014;51(4):247-58
pubmed: 25195856
Circulation. 2019 Apr 2;139(14):1710-1724
pubmed: 30586764
Breathe (Sheff). 2016 Mar;12(1):43-9
pubmed: 27066136
Brain Res Bull. 2000 Mar 15;51(5):363-9
pubmed: 10715555
Microcirculation. 2019 Nov;26(8):e12554
pubmed: 31066166
Am J Pathol. 2015 Jan;185(1):69-84
pubmed: 25447046
Int J Mol Sci. 2020 Oct 08;21(19):
pubmed: 33049983
Adv Exp Med Biol. 2018;1109:1-3
pubmed: 30523585
Am J Physiol Renal Physiol. 2021 Aug 1;321(2):F170-F178
pubmed: 34180718
Nature. 2020 Sep;585(7823):91-95
pubmed: 32788726
Stem Cells. 2015 Feb;33(2):557-73
pubmed: 25336400
Front Neurosci. 2021 Jun 18;15:629297
pubmed: 34239409
Eur Respir J. 2018 May 3;51(5):
pubmed: 29622568
Biomed Pharmacother. 2022 Dec;156:113928
pubmed: 36411618
Adv Exp Med Biol. 2019;1122:187-210
pubmed: 30937870
Inflamm Regen. 2022 Sep 26;42(1):44
pubmed: 36163271
Circ Res. 2023 Jan 6;132(1):109-126
pubmed: 36603064
Sci Rep. 2017 Jun 20;7(1):3855
pubmed: 28634350
Exp Ther Med. 2019 Nov;18(5):4022-4030
pubmed: 31611940
Am J Respir Cell Mol Biol. 2020 Jun;62(6):747-759
pubmed: 32084325
Br J Pharmacol. 2023 Sep;180(17):2196-2213
pubmed: 36908011
Int J Mol Sci. 2022 Sep 02;23(17):
pubmed: 36077398
Curr Tissue Microenviron Rep. 2020 Dec;1(4):163-169
pubmed: 33778770
Front Immunol. 2022 Dec 05;13:1014509
pubmed: 36544768
J Neuroinflammation. 2021 Dec 24;18(1):301
pubmed: 34952601
Rinsho Shinkeigaku. 2019 Nov 8;59(11):707-715
pubmed: 31656270
BMB Rep. 2022 Nov;55(11):565-570
pubmed: 36016502
Front Neuroenergetics. 2010 May 21;2:
pubmed: 20725515
Mol Med Rep. 2018 Apr;17(4):5484-5491
pubmed: 29393460
J Clin Invest. 2020 Jul 1;130(7):3833-3847
pubmed: 32343678
Animal Model Exp Med. 2023 Aug;6(4):337-345
pubmed: 37317664
Circulation. 2014 Apr 15;129(15):1586-97
pubmed: 24481949
Chin J Traumatol. 2020 Apr;23(2):89-95
pubmed: 32192909
Biochem Soc Trans. 2020 Feb 28;48(1):231-243
pubmed: 32096543
Nat Neurosci. 2016 May 26;19(6):771-83
pubmed: 27227366
Cells. 2021 May 28;10(6):
pubmed: 34071347
Sci Rep. 2015 Nov 13;5:16449
pubmed: 26563570
Am J Pathol. 2021 Nov;191(11):1917-1931
pubmed: 34329605
Biochem Biophys Res Commun. 2009 May 8;382(3):519-24
pubmed: 19289100
Front Immunol. 2016 Nov 04;7:480
pubmed: 27867386
Biomedicines. 2023 Feb 17;11(2):
pubmed: 36831136
Front Cell Dev Biol. 2020 Feb 14;8:77
pubmed: 32117997
Stem Cells. 2013 Feb;31(2):305-16
pubmed: 23165704
Transl Res. 2014 Apr;163(4):296-306
pubmed: 24530608
Cells. 2013 Sep 16;2(3):621-34
pubmed: 24709801
Front Oncol. 2020 Feb 25;10:188
pubmed: 32161718
Front Pharmacol. 2021 Apr 15;12:670813
pubmed: 33935795
Microvasc Res. 2023 Mar;146:104455
pubmed: 36396077
Cells. 2021 Mar 04;10(3):
pubmed: 33806335
Circ Res. 2005 Sep 16;97(6):512-23
pubmed: 16166562
Pulm Circ. 2020 Feb 28;10(1):
pubmed: 32166015
Neuro Oncol. 2005 Oct;7(4):452-64
pubmed: 16212810
Nat Commun. 2021 Sep 17;12(1):5501
pubmed: 34535655
Mediators Inflamm. 2019 May 7;2019:4123605
pubmed: 31205449
Nat Commun. 2018 Jun 22;9(1):2448
pubmed: 29934496
Glia. 2021 Oct;69(10):2474-2487
pubmed: 34152032
Biomolecules. 2022 Mar 22;12(4):
pubmed: 35454073
Nat Commun. 2017 Nov 17;8(1):1574
pubmed: 29146905
Bone Res. 2022 Mar 16;10(1):30
pubmed: 35296645
Rev Physiol Biochem Pharmacol. 2023;184:159-179
pubmed: 35380274
Am J Hematol. 2010 Aug;85(8):593-8
pubmed: 20540157
Tissue Eng Part B Rev. 2022 Feb;28(1):1-21
pubmed: 33231500
Front Cell Dev Biol. 2021 Jun 11;9:676342
pubmed: 34179005
Arterioscler Thromb Vasc Biol. 2020 Mar;40(3):766-782
pubmed: 31969018
ESC Heart Fail. 2022 Oct;9(5):3221-3231
pubmed: 35769011
ESC Heart Fail. 2022 Oct;9(5):3407-3417
pubmed: 35841124
Adv Exp Med Biol. 2019;1147:279-297
pubmed: 31147883