Thymoma patients with or without myasthenia gravis have increased Th17 cells, IL-17 production and ICOS expression.
Cytokines
Myasthenia gravis
T follicular helper cells
T peripheral helper cells
Thymoma
Journal
Journal of neuroimmunology
ISSN: 1872-8421
Titre abrégé: J Neuroimmunol
Pays: Netherlands
ID NLM: 8109498
Informations de publication
Date de publication:
15 08 2023
15 08 2023
Historique:
received:
06
03
2023
revised:
08
06
2023
accepted:
11
06
2023
medline:
2
8
2023
pubmed:
18
6
2023
entrez:
17
6
2023
Statut:
ppublish
Résumé
Thymoma associated myasthenia gravis (TAMG) is a small disease subgroup with autoantibodies against the acetylcholine receptor. The aim of this study was to assess the role of T helper (Th) cells in TAMG compared to thymoma patients without MG (TOMA) and healthy controls (HC). Peripheral blood cells were used for intracellular cytokine measurements and phenotyping of CD4
Identifiants
pubmed: 37329662
pii: S0165-5728(23)00115-7
doi: 10.1016/j.jneuroim.2023.578129
pii:
doi:
Substances chimiques
Interleukin-17
0
ICOS protein, human
0
Inducible T-Cell Co-Stimulator Protein
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
578129Informations de copyright
Copyright © 2023 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors have no conflicts of interest to declare that are relevant to the content of this article.