Scalable telomere-to-telomere assembly for diploid and polyploid genomes with double graph.

Journal

ArXiv
ISSN: 2331-8422
Titre abrégé: ArXiv
Pays: United States
ID NLM: 101759493

Informations de publication

Date de publication:
06 Jun 2023
Historique:
pubmed: 19 6 2023
medline: 19 6 2023
entrez: 19 6 2023
Statut: epublish

Résumé

Despite recent advances in the length and the accuracy of long-read data, building haplotype-resolved genome assemblies from telomere to telomere still requires considerable computational resources. In this study, we present an efficient

Identifiants

PMID: 37332563 PMC: PMC10274930
pubmed: 37332563
pii: 2306.03399
pmc: PMC10274930
pii:

Types de publication

Preprint

Langues

eng

Subventions

Organisme : NHGRI NIH HHS
ID : K99 HG012798
Pays : United States
Organisme : NHGRI NIH HHS
ID : R01 HG010040
Pays : United States
Organisme : NHGRI NIH HHS
ID : U01 HG010971
Pays : United States
Organisme : NHGRI NIH HHS
ID : U41 HG010972
Pays : United States

Auteurs

Haoyu Cheng (H)

Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.

Mobin Asri (M)

Genomics Institute, University of California, Santa Cruz, CA, USA.

Julian Lucas (J)

Genomics Institute, University of California, Santa Cruz, CA, USA.

Sergey Koren (S)

Genome Informatics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.

Heng Li (H)

Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.

Classifications MeSH