Structural insights into BCDX2 complex function in homologous recombination.


Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
Jul 2023
Historique:
received: 23 01 2023
accepted: 15 05 2023
pmc-release: 01 07 2024
medline: 21 7 2023
pubmed: 22 6 2023
entrez: 21 6 2023
Statut: ppublish

Résumé

Homologous recombination (HR) fulfils a pivotal role in the repair of DNA double-strand breaks and collapsed replication forks

Identifiants

pubmed: 37344589
doi: 10.1038/s41586-023-06219-w
pii: 10.1038/s41586-023-06219-w
pmc: PMC10712684
mid: NIHMS1947754
doi:

Substances chimiques

DNA, Single-Stranded 0
DNA-Binding Proteins 0
Multiprotein Complexes 0
Nucleoproteins 0
Protein Subunits 0
Rad51 Recombinase EC 2.7.7.-
RAD51B protein, human 0
RAD51C protein, human 0
RAD51D protein, human 0
XRCC2 protein, human 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

640-649

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM141091
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM115568
Pays : United States
Organisme : NIEHS NIH HHS
ID : P30 ES013508
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM128731
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM136717
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA188347
Pays : United States

Informations de copyright

© 2023. The Author(s), under exclusive licence to Springer Nature Limited.

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Auteurs

Yashpal Rawal (Y)

Department of Biochemistry & Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

Lijia Jia (L)

Department of Biochemistry & Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

Aviv Meir (A)

Department of Biochemistry and Molecular Biophysics, Columbia University Irving Medical Center, New York, NY, USA.

Shuo Zhou (S)

Department of Biochemistry & Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

Hardeep Kaur (H)

Department of Biochemistry & Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

Eliza A Ruben (EA)

Department of Biochemistry & Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

Youngho Kwon (Y)

Department of Biochemistry & Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

Kara A Bernstein (KA)

Department of Biochemistry & Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

Maria Jasin (M)

Developmental Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Alexander B Taylor (AB)

Department of Biochemistry & Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

Sandeep Burma (S)

Department of Biochemistry & Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Department of Neurosurgery, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

Robert Hromas (R)

Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

Alexander V Mazin (AV)

Department of Biochemistry & Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

Weixing Zhao (W)

Department of Biochemistry & Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

Daohong Zhou (D)

Department of Biochemistry & Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

Elizabeth V Wasmuth (EV)

Department of Biochemistry & Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

Eric C Greene (EC)

Department of Biochemistry and Molecular Biophysics, Columbia University Irving Medical Center, New York, NY, USA. ecg2108@cumc.columbia.edu.

Patrick Sung (P)

Department of Biochemistry & Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA. sungp@uthscsa.edu.

Shaun K Olsen (SK)

Department of Biochemistry & Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA. olsens@uthscsa.edu.
Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX, USA. olsens@uthscsa.edu.

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Classifications MeSH