Sandeep Burma

Affiliations

Department of Biochemistry and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.
Department of Neurosurgery, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.

Publications (22)

MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Gayathri Srinivasan , Elizabeth A Williamson , Kimi Kong , Aruna S Jaiswal , Guangcun Huang , Hyun-Suk Kim , Orlando Schärer , Weixing Zhao , Sandeep Burma , Patrick Sung , Robert Hromas

Therapy-Induced Senescence: Opportunities to Improve Anticancer Therapy.

Journal of the National Cancer Institute

Avec: Pataje G Prasanna , Deborah E Citrin , Jeffrey Hildesheim , Mansoor M Ahmed , Sundar Venkatachalam , Gabriela Riscuta , Dan Xi , Guangrong Zheng , Jan van Deursen , Jorg Goronzy , Stephen J Kron , Mitchell S Anscher , Norman E Sharpless , Judith Campisi , Stephen L Brown , Laura J Niedernhofer , Ana O'Loghlen , Alexandros G Georgakilas , Francois Paris , David Gius , David A Gewirtz , Clemens A Schmitt , Mohamed E Abazeed , James L Kirkland , Ann Richmond , Paul B Romesser , Scott W Lowe , Jesus Gil , Marc S Mendonca , Sandeep Burma , Daohong Zhou , C Norman Coleman

EGFR inhibition triggers an adaptive response by co-opting antiviral signaling pathways in lung cancer.

Nature cancer

Avec: Ke Gong , Gao Guo , Nishah Panchani , Matthew E Bender , David E Gerber , John D Minna , Farjana Fattah , Boning Gao , Michael Peyton , Kemp Kernstine , Bipasha Mukherjee , Sandeep Burma , Cheng-Ming Chiang , Shanrong Zhang , Adwait Amod Sathe , Chao Xing , Kathryn H Dao , Dawen Zhao , Esra A Akbay , Amyn A Habib

Bloom helicase mediates formation of large single-stranded DNA loops during DNA end processing.

Nature communications

Avec: Chaoyou Xue , Sameer J Salunkhe , Nozomi Tomimatsu , Ajinkya S Kawale , Youngho Kwon , Sandeep Burma , Patrick Sung , Eric C Greene

Selective Vulnerability of Senescent Glioblastoma Cells to BCL-XL Inhibition.

Molecular cancer research : MCR

Avec: Masum Rahman , Ian Olson , Moustafa Mansour , Lucas P Carlstrom , Rujapope Sutiwisesak , Rehan Saber , Karishma Rajani , Arthur E Warrington , Adam Howard , Mark Schroeder , Sisi Chen , Paul A Decker , Eliot F Sananikone , Yi Zhu , Tamar Tchkonia , Ian F Parney , Sandeep Burma , Desmond Brown , Moses Rodriguez , Jann N Sarkaria , James L Kirkland , Terry C Burns

An untapped window of opportunity for glioma: targeting therapy-induced senescence prior to recurrence.

NPJ precision oncology

Avec: Cecile Riviere-Cazaux , Lucas P Carlstrom , Bryan J Neth , Ian E Olson , Karishma Rajani , Masum Rahman , Samar Ikram , Moustafa A Mansour , Bipasha Mukherjee , Arthur E Warrington , Susan C Short , Thomas von Zglinicki , Desmond A Brown , Sandeep Burma , Tamar Tchkonia , Marissa J Schafer , Darren J Baker , Sani H Kizilbash , James L Kirkland , Terry C Burns

Distinct roles of the two BRCA2 DNA binding domains in DNA damage repair and replication fork preservation.

bioRxiv : the preprint server for biology

Avec: Francisco Neal , Wenjing Li , Mollie E Uhrig , Neelam Sharma , Shahrez Syed , Sandeep Burma , Robert Hromas , Alexander Mazin , Eloise Dray , David Libich , Shaun Olsen , Elizabeth Wasmuth , Weixing Zhao , Claus S Sørensen , Claudia Wiese , Youngho Kwon , Patrick Sung

Comprehensive targeting of resistance to inhibition of RTK signaling pathways by using glucocorticoids.

Nature communications

Avec: Ke Gong , Gao Guo , Nicole A Beckley , Xiaoyao Yang , Yue Zhang , David E Gerber , John D Minna , Sandeep Burma , Dawen Zhao , Esra A Akbay , Amyn A Habib

EGFR ligand shifts the role of EGFR from oncogene to tumour suppressor in EGFR-amplified glioblastoma by suppressing invasion through BIN3 upregulation.

Nature cell biology

Avec: Gao Guo , Ke Gong , Nicole Beckley , Yue Zhang , Xiaoyao Yang , Rati Chkheidze , Kimmo J Hatanpaa , Tomas Garzon-Muvdi , Prasad Koduru , Arifa Nayab , Jennifer Jenks , Adwait Amod Sathe , Yan Liu , Chao Xing , Shwu-Yuan Wu , Cheng-Ming Chiang , Bipasha Mukherjee , Sandeep Burma , Bryan Wohlfeld , Toral Patel , Bruce Mickey , Kalil Abdullah , Michael Youssef , Edward Pan , David E Gerber , Shulan Tian , Jann N Sarkaria , Samuel K McBrayer , Dawen Zhao , Amyn A Habib

DNA binding and RAD51 engagement by the BRCA2 C-terminus orchestrate DNA repair and replication fork preservation.

Nature communications

Avec: Youngho Kwon , Heike Rösner , Weixing Zhao , Platon Selemenakis , Zhuoling He , Ajinkya S Kawale , Jeffrey N Katz , Cody M Rogers , Francisco E Neal , Aida Badamchi Shabestari , Valdemaras Petrosius , Akhilesh K Singh , Marina Z Joel , Lucy Lu , Stephen P Holloway , Sandeep Burma , Bipasha Mukherjee , Robert Hromas , Alexander Mazin , Claudia Wiese , Claus S Sørensen , Patrick Sung

Specificity of end resection pathways for double-strand break regions containing ribonucleotides and base lesions.

Nature communications

Avec: James M Daley , Nozomi Tomimatsu , Grace Hooks , Weibin Wang , Adam S Miller , Xiaoyu Xue , Kevin A Nguyen , Hardeep Kaur , Elizabeth Williamson , Bipasha Mukherjee , Robert Hromas , Sandeep Burma , Patrick Sung

Radiation-Induced DNA Damage Cooperates with Heterozygosity of TP53 and PTEN to Generate High-Grade Gliomas.

Cancer research

Avec: Pavlina K Todorova , Eliot Fletcher-Sananikone , Bipasha Mukherjee , Rahul Kollipara , Vamsidhara Vemireddy , Xian-Jin Xie , Peter M Guida , Michael D Story , Kimmo Hatanpaa , Amyn A Habib , Ralf Kittler , Robert Bachoo , Robert Hromas , John R Floyd , Sandeep Burma

Elimination of Radiation-Induced Senescence in the Brain Tumor Microenvironment Attenuates Glioblastoma Recurrence.

Cancer research

Avec: Eliot Fletcher-Sananikone , Suman Kanji , Nozomi Tomimatsu , Luis Fernando Macedo Di Cristofaro , Rahul K Kollipara , Debabrata Saha , John R Floyd , Patrick Sung , Robert Hromas , Terry C Burns , Ralf Kittler , Amyn A Habib , Bipasha Mukherjee , Sandeep Burma

EEPD1 promotes repair of oxidatively-stressed replication forks.

NAR cancer

Avec: Aruna S Jaiswal , Hyun-Suk Kim , Orlando D Schärer , Neelam Sharma , Elizabeth A Williamson , Gayathri Srinivasan , Linda Phillips , Kimi Kong , Shailee Arya , Anurag Misra , Arijit Dutta , Yogesh Gupta , Christi A Walter , Sandeep Burma , Satya Narayan , Patrick Sung , Jac A Nickoloff , Robert Hromas

Efficacy of EGFR plus TNF inhibition in a preclinical model of temozolomide-resistant glioblastoma.

Neuro-oncology

Avec: Gao Guo , Ke Gong , Vineshkumar Thidil Puliyappadamba , Nishah Panchani , Edward Pan , Bipasha Mukherjee , Ziba Damanwalla , Sabrina Bharia , Kimmo J Hatanpaa , David E Gerber , Bruce E Mickey , Toral R Patel , Jann N Sarkaria , Dawen Zhao , Sandeep Burma , Amyn A Habib

Inhibition of the de novo pyrimidine biosynthesis pathway limits ribosomal RNA transcription causing nucleolar stress in glioblastoma cells.

PLoS genetics

Avec: M Carmen Lafita-Navarro , Niranjan Venkateswaran , Jessica A Kilgore , Suman Kanji , Jungsoo Han , Spencer Barnes , Noelle S Williams , Michael Buszczak , Sandeep Burma , Maralice Conacci-Sorrell

Targeting radioresistance and replication fork stability in prostate cancer.

JCI insight

Avec: Xiangyi Li , GuemHee Baek , Suzanne Carreira , Wei Yuan , Shihong Ma , Mia Hofstad , Sora Lee , Yunpeng Gao , Claudia Bertan , Maria de Los Dolores Fenor de la Maza , Prasanna G Alluri , Sandeep Burma , Benjamin Pc Chen , Ganesh V Raj , Johann de Bono , Yves Pommier , Ram S Mani

Regulation of TORC1 by MAPK Signaling Determines Sensitivity and Acquired Resistance to Trametinib in Pediatric BRAFV600E Brain Tumor Models.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Fuyang Li , Kathryn M Bondra , Samson Ghilu , Adam Studebaker , Qianqian Liu , Joel E Michalek , Mari Kogiso , Xiao-Nan Li , John A Kalapurakal , C David James , Sandeep Burma , Raushan T Kurmasheva , Peter J Houghton

Structural insights into BCDX2 complex function in homologous recombination.

Nature

Avec: Yashpal Rawal , Lijia Jia , Aviv Meir , Shuo Zhou , Hardeep Kaur , Eliza A Ruben , Youngho Kwon , Kara A Bernstein , Maria Jasin , Alexander B Taylor , Sandeep Burma , Robert Hromas , Alexander V Mazin , Weixing Zhao , Daohong Zhou , Elizabeth V Wasmuth , Eric C Greene , Patrick Sung , Shaun K Olsen

Crucial roles of the BRCA1-BARD1 E3 ubiquitin ligase activity in homology-directed DNA repair.

Molecular cell

Avec: Meiling Wang , Wenjing Li , Nozomi Tomimatsu , Corey H Yu , Jae-Hoon Ji , Salvador Alejo , Samuel R Witus , Dauren Alimbetov , O'Taveon Fitzgerald , Bo Wu , Qijing Wang , Yuxin Huang , Yaqi Gan , Felix Dong , Youngho Kwon , Gangadhara R Sareddy , Tyler J Curiel , Amyn A Habib , Robert Hromas , Carolina Dos Santos Passos , Tingting Yao , Dmitri N Ivanov , Peter S Brzovic , Sandeep Burma , Rachel E Klevit , Weixing Zhao

DSS1 restrains BRCA2's engagement with dsDNA for homologous recombination, replication fork protection, and R-loop homeostasis.

Nature communications

Avec: Yuxin Huang , Wenjing Li , Tzeh Foo , Jae-Hoon Ji , Bo Wu , Nozomi Tomimatsu , Qingming Fang , Boya Gao , Melissa Long , Jingfei Xu , Rouf Maqbool , Bipasha Mukherjee , Tengyang Ni , Salvador Alejo , Yuan He , Sandeep Burma , Li Lan , Bing Xia , Weixing Zhao

Promotion of DNA end resection by BRCA1-BARD1 in homologous recombination.

Nature

Avec: Sameer Salunkhe , James M Daley , Hardeep Kaur , Nozomi Tomimatsu , Chaoyou Xue , Vivek B Raina , Angela M Jasper , Cody M Rogers , Wenjing Li , Shuo Zhou , Rahul Mojidra , Youngho Kwon , Qingming Fang , Jae-Hoon Ji , Aida Badamchi Shabestari , O'Taveon Fitzgerald , Hoang Dinh , Bipasha Mukherjee , Amyn A Habib , Robert Hromas , Alexander V Mazin , Elizabeth V Wasmuth , Shaun K Olsen , David S Libich , Daohong Zhou , Weixing Zhao , Eric C Greene , Sandeep Burma , Patrick Sung

Réseau de co-auteurs

Robert Hromas 10 collaborations

Bipasha Mukherjee 10 collaborations

Patrick Sung 9 collaborations

Amyn A Habib 8 collaborations

Weixing Zhao 7 collaborations

Nozomi Tomimatsu 6 collaborations

Youngho Kwon 6 collaborations

Ke Gong 4 collaborations

Gao Guo 4 collaborations

David E Gerber 4 collaborations

Dawen Zhao 4 collaborations

Wenjing Li 4 collaborations

James L Kirkland 3 collaborations

Daohong Zhou 3 collaborations

Eric C Greene 3 collaborations

Jann N Sarkaria 3 collaborations

Terry C Burns 3 collaborations

Hardeep Kaur 3 collaborations

Jae-Hoon Ji 3 collaborations

Gayathri Srinivasan 2 collaborations

Elizabeth A Williamson 2 collaborations

Kimi Kong 2 collaborations

Aruna S Jaiswal 2 collaborations

Hyun-Suk Kim 2 collaborations

Nishah Panchani 2 collaborations

John D Minna 2 collaborations

Cheng-Ming Chiang 2 collaborations

Adwait Amod Sathe 2 collaborations

Chao Xing 2 collaborations

Esra A Akbay 2 collaborations

Chaoyou Xue 2 collaborations

Ajinkya S Kawale 2 collaborations

Masum Rahman 2 collaborations

Lucas P Carlstrom 2 collaborations

Karishma Rajani 2 collaborations

Arthur E Warrington 2 collaborations

Tamar Tchkonia 2 collaborations

Neelam Sharma 2 collaborations

Alexander Mazin 2 collaborations

Claus S Sørensen 2 collaborations

Claudia Wiese 2 collaborations

Xiaoyao Yang 2 collaborations

Yue Zhang 2 collaborations

Kimmo J Hatanpaa 2 collaborations

Edward Pan 2 collaborations

Cody M Rogers 2 collaborations

Aida Badamchi Shabestari 2 collaborations

James M Daley 2 collaborations

Eliot Fletcher-Sananikone 2 collaborations

Ralf Kittler 2 collaborations

John R Floyd 2 collaborations

Suman Kanji 2 collaborations

Shuo Zhou 2 collaborations

Alexander V Mazin 2 collaborations

Elizabeth V Wasmuth 2 collaborations

Shaun K Olsen 2 collaborations

Salvador Alejo 2 collaborations

O'Taveon Fitzgerald 2 collaborations

Bo Wu 2 collaborations

Yuxin Huang 2 collaborations

Qingming Fang 2 collaborations

Guangcun Huang 1 collaboration

Orlando Schärer 1 collaboration

Pataje G Prasanna 1 collaboration

Deborah E Citrin 1 collaboration

Jeffrey Hildesheim 1 collaboration

Mansoor M Ahmed 1 collaboration

Sundar Venkatachalam 1 collaboration

Gabriela Riscuta 1 collaboration

Dan Xi 1 collaboration

Guangrong Zheng 1 collaboration

Jan van Deursen 1 collaboration

Jorg Goronzy 1 collaboration

Stephen J Kron 1 collaboration

Mitchell S Anscher 1 collaboration

Norman E Sharpless 1 collaboration

Judith Campisi 1 collaboration

Stephen L Brown 1 collaboration

Laura J Niedernhofer 1 collaboration

Ana O'Loghlen 1 collaboration

Alexandros G Georgakilas 1 collaboration

Francois Paris 1 collaboration

David Gius 1 collaboration

David A Gewirtz 1 collaboration

Clemens A Schmitt 1 collaboration

Mohamed E Abazeed 1 collaboration

Ann Richmond 1 collaboration

Paul B Romesser 1 collaboration

Scott W Lowe 1 collaboration

Jesus Gil 1 collaboration

Marc S Mendonca 1 collaboration

C Norman Coleman 1 collaboration

Matthew E Bender 1 collaboration

Farjana Fattah 1 collaboration

Boning Gao 1 collaboration

Michael Peyton 1 collaboration

Kemp Kernstine 1 collaboration

Shanrong Zhang 1 collaboration

Kathryn H Dao 1 collaboration

Sameer J Salunkhe 1 collaboration

Ian Olson 1 collaboration

Moustafa Mansour 1 collaboration

Rujapope Sutiwisesak 1 collaboration

Rehan Saber 1 collaboration

Adam Howard 1 collaboration

Mark Schroeder 1 collaboration

Sisi Chen 1 collaboration

Paul A Decker 1 collaboration

Eliot F Sananikone 1 collaboration

Yi Zhu 1 collaboration

Ian F Parney 1 collaboration

Desmond Brown 1 collaboration

Moses Rodriguez 1 collaboration

Cecile Riviere-Cazaux 1 collaboration

Bryan J Neth 1 collaboration

Ian E Olson 1 collaboration

Samar Ikram 1 collaboration

Moustafa A Mansour 1 collaboration

Susan C Short 1 collaboration

Thomas von Zglinicki 1 collaboration

Desmond A Brown 1 collaboration

Marissa J Schafer 1 collaboration

Darren J Baker 1 collaboration

Sani H Kizilbash 1 collaboration

Francisco Neal 1 collaboration

Mollie E Uhrig 1 collaboration

Shahrez Syed 1 collaboration

Eloise Dray 1 collaboration

David Libich 1 collaboration

Shaun Olsen 1 collaboration

Elizabeth Wasmuth 1 collaboration

Nicole A Beckley 1 collaboration

Nicole Beckley 1 collaboration

Rati Chkheidze 1 collaboration

Tomas Garzon-Muvdi 1 collaboration

Prasad Koduru 1 collaboration

Arifa Nayab 1 collaboration

Jennifer Jenks 1 collaboration

Yan Liu 1 collaboration

Shwu-Yuan Wu 1 collaboration

Bryan Wohlfeld 1 collaboration

Toral Patel 1 collaboration

Bruce Mickey 1 collaboration

Kalil Abdullah 1 collaboration

Michael Youssef 1 collaboration

Shulan Tian 1 collaboration

Samuel K McBrayer 1 collaboration

Heike Rösner 1 collaboration

Platon Selemenakis 1 collaboration

Zhuoling He 1 collaboration

Jeffrey N Katz 1 collaboration

Francisco E Neal 1 collaboration

Valdemaras Petrosius 1 collaboration

Akhilesh K Singh 1 collaboration

Marina Z Joel 1 collaboration

Lucy Lu 1 collaboration

Stephen P Holloway 1 collaboration

Grace Hooks 1 collaboration

Weibin Wang 1 collaboration

Adam S Miller 1 collaboration

Xiaoyu Xue 1 collaboration

Kevin A Nguyen 1 collaboration

Elizabeth Williamson 1 collaboration

Pavlina K Todorova 1 collaboration

Rahul Kollipara 1 collaboration

Vamsidhara Vemireddy 1 collaboration

Xian-Jin Xie 1 collaboration

Peter M Guida 1 collaboration

Michael D Story 1 collaboration

Kimmo Hatanpaa 1 collaboration

Robert Bachoo 1 collaboration

Luis Fernando Macedo Di Cristofaro 1 collaboration

Rahul K Kollipara 1 collaboration

Debabrata Saha 1 collaboration

Orlando D Schärer 1 collaboration

Linda Phillips 1 collaboration

Shailee Arya 1 collaboration

Anurag Misra 1 collaboration

Arijit Dutta 1 collaboration

Yogesh Gupta 1 collaboration

Christi A Walter 1 collaboration

Satya Narayan 1 collaboration

Jac A Nickoloff 1 collaboration

Vineshkumar Thidil Puliyappadamba 1 collaboration

Ziba Damanwalla 1 collaboration

Sabrina Bharia 1 collaboration

Bruce E Mickey 1 collaboration

Toral R Patel 1 collaboration

M Carmen Lafita-Navarro 1 collaboration

Niranjan Venkateswaran 1 collaboration

Jessica A Kilgore 1 collaboration

Jungsoo Han 1 collaboration

Spencer Barnes 1 collaboration

Noelle S Williams 1 collaboration

Michael Buszczak 1 collaboration

Maralice Conacci-Sorrell 1 collaboration

Xiangyi Li 1 collaboration

GuemHee Baek 1 collaboration

Suzanne Carreira 1 collaboration

Wei Yuan 1 collaboration

Shihong Ma 1 collaboration

Mia Hofstad 1 collaboration

Sora Lee 1 collaboration

Yunpeng Gao 1 collaboration

Claudia Bertan 1 collaboration

Maria de Los Dolores Fenor de la Maza 1 collaboration

Prasanna G Alluri 1 collaboration

Benjamin Pc Chen 1 collaboration

Ganesh V Raj 1 collaboration

Johann de Bono 1 collaboration

Yves Pommier 1 collaboration

Ram S Mani 1 collaboration

Fuyang Li 1 collaboration

Kathryn M Bondra 1 collaboration

Samson Ghilu 1 collaboration

Adam Studebaker 1 collaboration

Qianqian Liu 1 collaboration

Joel E Michalek 1 collaboration

Mari Kogiso 1 collaboration

Xiao-Nan Li 1 collaboration

John A Kalapurakal 1 collaboration

C David James 1 collaboration

Raushan T Kurmasheva 1 collaboration

Peter J Houghton 1 collaboration

Yashpal Rawal 1 collaboration

Lijia Jia 1 collaboration

Aviv Meir 1 collaboration

Eliza A Ruben 1 collaboration

Kara A Bernstein 1 collaboration

Maria Jasin 1 collaboration

Alexander B Taylor 1 collaboration

Meiling Wang 1 collaboration

Corey H Yu 1 collaboration

Samuel R Witus 1 collaboration

Dauren Alimbetov 1 collaboration

Qijing Wang 1 collaboration

Yaqi Gan 1 collaboration

Felix Dong 1 collaboration

Gangadhara R Sareddy 1 collaboration

Tyler J Curiel 1 collaboration

Carolina Dos Santos Passos 1 collaboration

Tingting Yao 1 collaboration

Dmitri N Ivanov 1 collaboration

Peter S Brzovic 1 collaboration

Rachel E Klevit 1 collaboration

Tzeh Foo 1 collaboration

Boya Gao 1 collaboration

Melissa Long 1 collaboration

Jingfei Xu 1 collaboration

Rouf Maqbool 1 collaboration

Tengyang Ni 1 collaboration

Yuan He 1 collaboration

Li Lan 1 collaboration

Bing Xia 1 collaboration

Sameer Salunkhe 1 collaboration

Vivek B Raina 1 collaboration

Angela M Jasper 1 collaboration

Rahul Mojidra 1 collaboration

Hoang Dinh 1 collaboration

David S Libich 1 collaboration