Analysis of Patulin in Apple Products Marketed in Belgium: Intra-Laboratory Validation Study and Occurrence.


Journal

Toxins
ISSN: 2072-6651
Titre abrégé: Toxins (Basel)
Pays: Switzerland
ID NLM: 101530765

Informations de publication

Date de publication:
30 05 2023
Historique:
received: 14 04 2023
revised: 23 05 2023
accepted: 25 05 2023
medline: 29 6 2023
pubmed: 27 6 2023
entrez: 27 6 2023
Statut: epublish

Résumé

Apple and apple derivatives (e.g., juices, puree) are the most important foodstuffs contaminated with patulin (PAT) in the human diet. To routinely monitor these foodstuffs and ensure that the PAT levels are below the maximum permitted levels, a method using liquid chromatography combined with tandem mass spectrometry (LC-MS/MS) has been developed. Afterwards, the method was successfully validated, reaching quantification limits of 1.2 μg/L for apple juice and cider, and 2.1 μg/kg for puree. Recovery experiments were performed with samples fortified with PAT in the range of 25-75 μg/L for juice/cider and 25-75 μg/kg for puree. The results show overall average recovery rates of 85% (RSD

Identifiants

pubmed: 37368669
pii: toxins15060368
doi: 10.3390/toxins15060368
pmc: PMC10302775
pii:
doi:

Substances chimiques

Patulin 95X2BV4W8R

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Références

Food Addit Contam. 2000 May;17(5):399-406
pubmed: 10945107
IARC Monogr Eval Carcinog Risks Hum. 2002;82:1-556
pubmed: 12687954
Int J Food Microbiol. 2007 Nov 1;119(3):170-81
pubmed: 17900726
Compr Rev Food Sci Food Saf. 2005 Jan;4(1):8-21
pubmed: 33430570
J Food Prot. 2006 Jun;69(6):1371-8
pubmed: 16786859
Anal Bioanal Chem. 2015 Jul;407(18):5433-42
pubmed: 25925860
Food Addit Contam. 2002 Apr;19(4):387-99
pubmed: 11962697
J Food Prot. 2014 Jun;77(6):963-71
pubmed: 24853519
Mycotoxin Res. 2021 May;37(2):119-127
pubmed: 33619699
J Agric Food Chem. 2017 Jun 21;65(24):5064-5073
pubmed: 28581742
Food Chem Toxicol. 2019 Jul;129:249-256
pubmed: 31042591
J Food Prot. 2010 Jan;73(1):69-74
pubmed: 20051206
Food Chem Toxicol. 1993 Jun;31(6):455-6
pubmed: 8514218
Mol Nutr Food Res. 2013 Jan;57(1):165-86
pubmed: 23047235
Rapid Commun Mass Spectrom. 2006;20(18):2649-59
pubmed: 16912987
Toxins (Basel). 2010 Apr;2(4):613-31
pubmed: 22069602
Toxins (Basel). 2020 Jan 16;12(1):
pubmed: 31963183
J AOAC Int. 2000 Nov-Dec;83(6):1387-94
pubmed: 11128142
Food Addit Contam. 2003 May;20(5):482-9
pubmed: 12775467
Food Sci Nutr. 2021 Jun 21;9(8):4211-4220
pubmed: 34401072
J Food Sci. 2011 Mar;76(2):H62-71
pubmed: 21535769
Anal Methods. 2021 Jan 21;13(2):192-201
pubmed: 33331361

Auteurs

Emmanuel K Tangni (EK)

Sciensano, Chemical and Physical Health Risks, Organic Contaminants and Additives, Toxins Unit, Leuvensesteenweg 17, 3080 Tervuren, Belgium.

Julien Masquelier (J)

Sciensano, Chemical and Physical Health Risks, Organic Contaminants and Additives, Toxins Unit, Leuvensesteenweg 17, 3080 Tervuren, Belgium.

Els Van Hoeck (E)

Sciensano, Chemical and Physical Health Risks, Organic Contaminants and Additives, Toxins Unit, Leuvensesteenweg 17, 3080 Tervuren, Belgium.

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Classifications MeSH