Distinct dynamic behavioural response to social exclusion in male patients with a history of alcohol dependence.
IL-1b
alcohol dependence
behavioural response
social exclusion
Journal
Addiction biology
ISSN: 1369-1600
Titre abrégé: Addict Biol
Pays: United States
ID NLM: 9604935
Informations de publication
Date de publication:
07 2023
07 2023
Historique:
revised:
15
03
2023
received:
31
10
2022
accepted:
27
04
2023
medline:
29
6
2023
pubmed:
27
6
2023
entrez:
27
6
2023
Statut:
ppublish
Résumé
Social exclusion contributes to alcohol consumption, whereas the development of alcohol dependence (AD) can in turn lead to the social exclusion of people with AD. Previous research observed altered neural responses to experimentally induced social exclusion (i.e., Cyberball game) in patients with AD. In addition, inflammation has been associated with both social behaviours and AD. Our study aimed to investigate the dynamic behavioural response and the inflammatory effects of social exclusion in male patients with a history of AD. To this end, we analysed dynamic changes in ball tossing during a partial exclusion Cyberball game and the cytokine interleukin (IL)-1b in saliva in 31 male patients who had a history of AD and 29 gender-matched healthy controls without AD. Participants were included in the first 2 min of the Cyberball game and then excluded by one of the two co-players in the proceeding 5 min. Saliva was collected three times: one before and two after the Cyberball game. Across groups, participants passed the ball more often to the excluder during the partial exclusion period. Analysis using piece-wise linear mixed models showed that patients rapidly increased ball tosses to the excluder upon exclusion, which lasted to the late response phase, whereas the early behavioural response to exclusion took longer for controls. There was no significant change of salivary IL-1b level to exclusion in either patients or controls. The results indicate a distinct dynamic behavioural response to social exclusion in male patients with a history of AD.
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e13287Informations de copyright
© 2023 The Authors. Addiction Biology published by John Wiley & Sons Ltd on behalf of Society for the Study of Addiction.
Références
Heinz AJ, Beck A, Meyer-Lindenberg A, Sterzer P, Heinz A. Cognitive and neurobiological mechanisms of alcohol-related aggression. Nat Rev Neurosci. 2011;12(7):400-413. doi:10.1038/nrn3042
Laws HB, Ellerbeck NE, Rodrigues AS, Simmons JA, Ansell EB. Social rejection and alcohol use in daily life. Alcohol Clin Exp Res. 2017;41(4):820-827. doi:10.1111/acer.13347
Venniro M, Zhang M, Caprioli D, et al. Volitional social interaction prevents drug addiction in rat models. Nat Neurosci. 2018;21(11):1520-1529. doi:10.1038/s41593-018-0246-6
Schomerus G, Lucht M, Holzinger A, Matschinger H, Carta MG, Angermeyer MC. The stigma of alcohol dependence compared with other mental disorders: a review of population studies. Alcohol Alcohol. 2011;46(2):105-112. doi:10.1093/alcalc/agq089
Cassidy T, Giles M, Carey A. Attachment, rejection sensitivity, support, psychological capital and alcohol dependency in students. Int J Contemp Res Soc Sci. 2021;3(4):69-77. doi:10.33094/26410249.2021.34.69.77
Nepon T, Pepler DJ, Craig WM, Connolly J, Flett GL. A longitudinal analysis of peer victimization, self-esteem, and rejection sensitivity in mental health and substance use among adolescents. Int J Ment Health Addict. 2021;19(4):1135-1148. doi:10.1007/s11469-019-00215-w
Bach P, Frischknecht U, Klinkowski S, et al. Higher social rejection sensitivity in opioid-dependent patients is related to smaller insula gray matter volume: a voxel-based morphometric study. Soc Cogn Affect Neurosci. 2019;14(11):1187-1195. doi:10.1093/scan/nsz094
Weinstein A, Abu HB, Timor A, Mama Y. Delay discounting, risk-taking, and rejection sensitivity among individuals with internet and video gaming disorders. J Behav Addict. 2016;5(4):674-682. doi:10.1556/2006.5.2016.081
Wesselmann ED, Parris L. Exploring the links between social exclusion and substance use, misuse, and addiction. Front Psychol. 2021;12:674743. doi:10.3389/fpsyg.2021.674743
Brandt L, Liu S, Heim C, Heinz A. The effects of social isolation stress and discrimination on mental health. Transl Psychiatry. 2022;12(1):398. doi:10.1038/s41398-022-02178-4
Heilig M, Epstein DH, Nader MA, Shaham Y. Time to connect: bringing social context into addiction neuroscience. Nat Rev Neurosci. 2016;17(9):592-599. doi:10.1038/nrn.2016.67
Williams KD. Ostracism. Annu Rev Psychol. 2007;58(1):425-452. doi:10.1146/annurev.psych.58.110405.085641
Williams KD. Ostracism: a temporal need-threat model. Adv Exp Soc Psychol. 2009;41:275-314. doi:10.1016/S0065-2601(08)00406-1
Eisenberger NI, Lieberman MD. Why rejection hurts: a common neural alarm system for physical and social pain. Trends Cogn Sci. 2004;8(7):294-300. doi:10.1016/j.tics.2004.05.010
Macdonald G, Leary MR. Why does social exclusion hurt? The relationship between social and physical pain. Psychol Bull. 2005;131(2):202-223. doi:10.1037/0033-2909.131.2.202
Hales AH, Williams KD, Eckhardt CI. A participant walks into a bar …: subjective intoxication buffers ostracism's negative effects. Soc Psychol. 2015;46(3):157-166. doi:10.1027/1864-9335/a000235
Fairbairn CE, Creswell KG, Hales AH, Williams KD, Wilkins KV. Mixing misery and gin: the effect of alcohol administration on ostracism response. Pers Soc Psychol Bull. 2021;48(8):1269-1283. doi:10.1177/01461672211038450
Maurage P, Joassin F, Philippot P, et al. Disrupted regulation of social exclusion in alcohol-dependence: an fMRI study. Neuropsychopharmacology. 2012;37(9):2067-2075. doi:10.1038/npp.2012.54
Chernyak N, Zayas V. Being excluded by one means being excluded by all: perceiving exclusion from inclusive others during one-person social exclusion. J Exp Soc Psychol. 2010;46(3):582-585. doi:10.1016/j.jesp.2010.01.004
Critcher CR, Zayas V. The involuntary excluder effect: those included by an excluder are seen as exclusive themselves. J Pers Soc Psychol. 2014;107(3):454-474. doi:10.1037/a0036951
Gutz L, Küpper C, Renneberg B, Niedeggen M. Processing social participation: an event-related brain potential study. Neuroreport. 2011;22(9):453-458. doi:10.1097/WNR.0b013e3283476b67
Dewald-Kaufmann JF, Wüstenberg T, Barton BB, et al. Dynamics of the immediate behavioral response to partial social exclusion. Sci Rep. 2021;11(1):1853. doi:10.1038/s41598-020-80039-0
Maner JK, DeWall CN, Baumeister RF, Schaller M. Does social exclusion motivate interpersonal reconnection? Resolving the “porcupine problem”. J Pers Soc Psychol. 2007;92(1):42-55. doi:10.1037/0022-3514.92.1.42
Smart Richman L, Leary MR. Reactions to discrimination, stigmatization, ostracism, and other forms of interpersonal rejection: a multimotive model. Psychol Rev. 2009;116(2):365-383. doi:10.1037/a0015250
Bernstein MJ, Sacco DF, Brown CM, Young SG, Claypool HM. A preference for genuine smiles following social exclusion. J Exp Soc Psychol. 2010;46(1):196-199. doi:10.1016/j.jesp.2009.08.010
Lakin JL, Chartrand TL, Arkin RM. I am too just like you: nonconscious mimicry as an automatic behavioral response to social exclusion. Psychol Sci. 2008;19(8):816-822. doi:10.1111/j.1467-9280.2008.02162.x
Reinhard MA, Dewald-Kaufmann J, Wüstenberg T, et al. The vicious circle of social exclusion and psychopathology: a systematic review of experimental ostracism research in psychiatric disorders. Eur Arch Psychiatry Clin Neurosci. 2020;270(5):521-532. doi:10.1007/s00406-019-01074-1
Frischknecht U, Beckmann B, Heinrich M, et al. The vicious circle of perceived stigmatization, depressiveness, anxiety, and low quality of life in substituted heroin addicts. Eur Addict Res. 2011;17(5):241-249. doi:10.1159/000328637
Kawamoto T, Nittono H, Ura M. Trait rejection sensitivity is associated with vigilance and defensive response rather than detection of social rejection cues. Front Psychol. 2015;6:1516. doi:10.3389/fpsyg.2015.01516
Eisenberger NI, Moieni M, Inagaki TK, Muscatell KA, Irwin MR. In sickness and in health: the co-regulation of inflammation and social behavior. Neuropsychopharmacology. 2017;42(1):242-253. doi:10.1038/npp.2016.141
Heinz A, Hermann D, Smolka MN, et al. Effects of acute psychological stress on adhesion molecules, interleukins and sex hormones: implications for coronary heart disease. Psychopharmacology (Berl). 2003;165(2):111-117. doi:10.1007/s00213-002-1244-6
Adams C, Conigrave JH, Lewohl J, Haber P, Morley KC. Alcohol use disorder and circulating cytokines: a systematic review and meta-analysis. Brain Behav Immun. 2020;89:501-512. doi:10.1016/j.bbi.2020.08.002
Marsland AL, Walsh C, Lockwood K, John-Henderson NA. The effects of acute psychological stress on circulating and stimulated inflammatory markers: a systematic review and meta-analysis. Brain Behav Immun. 2017;64:208-219. doi:10.1016/j.bbi.2017.01.011
Slavich GM, Way BM, Eisenberger NI, Taylor SE. Neural sensitivity to social rejection is associated with inflammatory responses to social stress. Proc Natl Acad Sci U S A. 2010;107(33):14817-14822. doi:10.1073/pnas.1009164107
Scotti M-AL, Carlton ED, Demas GE, Grippo AJ. Social isolation disrupts innate immune responses in both male and female prairie voles and enhances agonistic behavior in female prairie voles (Microtus ochrogaster). Horm Behav. 2015;70:7-13. doi:10.1016/j.yhbeh.2015.01.004
Pastor IJ, Laso FJ, Romero A, González-Sarmiento R. Interleukin-1 gene cluster polymorphisms and alcoholism in Spanish men. Alcohol Alcohol. 2005;40(3):181-186. doi:10.1093/alcalc/agh153
Leclercq S, De Saeger C, Delzenne N, de Timary P, Stärkel P. Role of inflammatory pathways, blood mononuclear cells, and gut-derived bacterial products in alcohol dependence. Biol Psychiatry. 2014;76(9):725-733. doi:10.1016/j.biopsych.2014.02.003
Sebold M, Nebe S, Garbusow M, et al. When habits are dangerous: alcohol expectancies and habitual decision making predict relapse in alcohol dependence. Biol Psychiatry. 2017;82(11):847-856. doi:10.1016/j.biopsych.2017.04.019
Sebold M, Garbusow M, Cerci D, et al. Association of the OPRM1 A118G polymorphism and Pavlovian-to-instrumental transfer: clinical relevance for alcohol dependence. J Psychopharmacol. 2021;35(5):566-578. doi:10.1177/0269881121991992
American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed, Text Revision. American Psychiatric Association; 2000.
Rumpf HJ, Hapke U, Meyer C, John U. Screening for alcohol use disorders and at-risk drinking in the general population: psychometric performance of three questionnaires. Alcohol Alcohol. 2002;37(3):261-268. doi:10.1093/alcalc/37.3.261
Williams KD, Sommer KL. Social ostracism by coworkers: does rejection lead to loafing or compensation? Pers Soc Psychol Bull. 1997;23(7):693-706. doi:10.1177/0146167297237003
Prather AA, Carroll JE, Fury JM, McDade KK, Ross D, Marsland AL. Gender differences in stimulated cytokine production following acute psychological stress. Brain Behav Immun. 2009;23(5):622-628. doi:10.1016/j.bbi.2008.11.004
Alcohol Facts and Statistics. National Institute on Alcohol Abuse and Alcoholism. https://www.niaaa.nih.gov/publications/brochures-and-fact-sheets/alcohol-facts-and-statistics Published 2022. Accessed.
Lange T, Dimitrov S, Born J. Effects of sleep and circadian rhythm on the human immune system. Ann N Y Acad Sci. 2010;1193(1):48-59. doi:10.1111/j.1749-6632.2009.05300.x
Reinhard MA, Padberg F, Dewald-Kaufmann J, et al. Sequential social exclusion in a novel Cyberball paradigm leads to reduced behavioral repair and plasma oxytocin in borderline personality disorder. J Pers Disord. 2022;36(1):99-115. doi:10.1521/pedi_2021_35_532
Ebner NC, Riediger M, Lindenberger U. FACES-A database of facial expressions in young, middle-aged, and older women and men: development and validation. Behav Res Methods. 2010;42(1):351-362. doi:10.3758/BRM.42.1.351
Jobst A, Sabass L, Palagyi A, et al. Effects of social exclusion on emotions and oxytocin and cortisol levels in patients with chronic depression. J Psychiatr Res. 2015;60:170-177. doi:10.1016/j.jpsychires.2014.11.001
Jamieson JP, Harkins SG, Williams KD. Need threat can motivate performance after ostracism. Pers Soc Psychol Bull. 2010;36(5):690-702. doi:10.1177/0146167209358882
Leary MR, Kelly KM, Cottrell CA, Schreindorfer LS. Construct validity of the need to belong scale: mapping the nomological network. J Pers Assess. 2013;95(6):610-624. doi:10.1080/00223891.2013.819511
Staebler K, Helbing E, Rosenbach C, Renneberg B. Rejection sensitivity and borderline personality disorder. Clin Psychol Psychother. 2011;18(4):275-283. doi:10.1002/cpp.705
Niu G-f, Shi X-h, Yao L-s, Yang W-c, Jin S-y, Xu L. Social exclusion and depression among undergraduate students: the mediating roles of rejection sensitivity and social self-efficacy. Curr Psychol. 2022;1-10. doi:10.1007/s12144-022-03318-1
Petermann F. Hospital anxiety and depression scale, Deutsche version (HADS-D). Z Fur Psychiatr Psychol Psychother. 2015;64(2):83-86. doi:10.1024/1661-4747/a000265
Klinitzke G, Romppel M, Häuser W, Brähler E, Glaesmer H. The German version of the Childhood Trauma Questionnaire (CTQ): psychometric characteristics in a representative sample of the general population. Psychother Psychosom Med Psychol. 2012;62(2):47-51. doi:10.1055/s-0031-1295495
Paulus C. Der Saarbrücker Persönlichkeitsfragebogen SPF (IRI) zur Messung von Empathie. Psychometrische Evaluation der deutschen Version des Interpersonal Reactivity Index 2009.
Gross JJ, John OP. Individual differences in two emotion regulation processes: implications for affect, relationships, and well-being. J Pers Soc Psychol. 2003;85(2):348-362. doi:10.1037/0022-3514.85.2.348
Brady KT, Back SE. Childhood trauma, posttraumatic stress disorder, and alcohol dependence. Alcohol Res. 2012;34(4):408-413.
Le Berre A-P. Emotional processing and social cognition in alcohol use disorder. Neuropsychology. 2019;33(6):808-821. doi:10.1037/neu0000572
Slavish DC, Graham-Engeland JE, Smyth JM, Engeland CG. Salivary markers of inflammation in response to acute stress. Brain Behav Immun. 2015;44:253-269. doi:10.1016/j.bbi.2014.08.008
[dataset] Chen K. (2022, October 29). Distinct dynamic behavioral response to social exclusion in patients with a history of alcohol dependence. Retrieved from osf.io/753ds. In.
Wetzels R, Matzke D, Lee MD, Rouder JN, Iverson GJ, Wagenmakers EJ. Statistical evidence in experimental psychology: an empirical comparison using 855 t tests. Perspect Psychol Sci. 2011;6(3):291-298. doi:10.1177/1745691611406923
Hsu DT, Jarcho JM. Next up for psychiatry: rejection sensitivity and the social brain. Neuropsychopharmacology. 2021;46(1):239-240. doi:10.1038/s41386-020-00802-9
Mastrolonardo M, Alicino D, Zefferino R, Pasquini P, Picardi A. Effect of psychological stress on salivary interleukin-1beta in psoriasis. Arch Med Res. 2007;38(2):206-211. doi:10.1016/j.arcmed.2006.09.009
Mahmood AA, Leka'a MI. Effect of the examination stress on periodontal health status and salivary IL-1? Among Iraqi dental students. J Baghdad Coll Dent. 2013;25(4):72-78. doi:10.12816/0015069
Seidel EM, Silani G, Metzler H, et al. The impact of social exclusion vs. inclusion on subjective and hormonal reactions in females and males. Psychoneuroendocrinology. 2013;38(12):2925-2932. doi:10.1016/j.psyneuen.2013.07.021
Gaffey AE, Wirth MM. Stress, rejection, and hormones: cortisol and progesterone reactivity to laboratory speech and rejection tasks in women and men. F1000Res. 2014;3:208. doi:10.12688/f1000research.5142.1
Szabo YZ, Slavish DC. Measuring salivary markers of inflammation in health research: a review of methodological considerations and best practices. Psychoneuroendocrinology. 2021;124:105069. doi:10.1016/j.psyneuen.2020.105069
Muscatell KA, Inagaki TK. Beyond social withdrawal: new perspectives on the effects of inflammation on social behavior. Brain Behav Immun Health. 2021;16:100302. doi:10.1016/j.bbih.2021.100302
Zadro L, Williams KD, Richardson R. How low can you go? Ostracism by a computer is sufficient to lower self-reported levels of belonging, control, self-esteem, and meaningful existence. J Exp Soc Psychol. 2004;40(4):560-567. doi:10.1016/j.jesp.2003.11.006
Heinz A, Kiefer F, Smolka MN, et al. Addiction research consortium: losing and regaining control over drug intake (ReCoDe)-from trajectories to mechanisms and interventions. Addict Biol. 2020;25(2):e12866. doi:10.1111/adb.12866