Intracellular Redox Behavior of Quercetin and Resveratrol Singly and in Mixtures.
CM-H2DCFDA
antioxidant
mixture
pro-oxidant
quercetin
resveratrol
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
09 Jun 2023
09 Jun 2023
Historique:
received:
15
05
2023
revised:
02
06
2023
accepted:
05
06
2023
medline:
29
6
2023
pubmed:
28
6
2023
entrez:
28
6
2023
Statut:
epublish
Résumé
Polyphenols have attracted great interest as potent antioxidant compounds and nutraceuticals; however, their antioxidant properties represent a multifaceted phenomenon, including pro-oxidant effects under particular conditions and complex behavior when multiple polyphenols are simultaneously present. Moreover, their intracellular behavior cannot always be predicted from their ability to counteract the production of ROS in acellular assays. The present work aimed to study the direct intracellular redox activity of two polyphenols, resveratrol and quercetin, singly and in mixture in a cellular short-term bioassay under both basal and pro-oxidant conditions. The study was carried out by spectrofluorimetric assessment of the intracellular fluorescence of CM-H
Identifiants
pubmed: 37375237
pii: molecules28124682
doi: 10.3390/molecules28124682
pmc: PMC10301869
pii:
doi:
Substances chimiques
Resveratrol
Q369O8926L
Quercetin
9IKM0I5T1E
Antioxidants
0
Reactive Oxygen Species
0
Hydrogen Peroxide
BBX060AN9V
Polyphenols
0
Stilbenes
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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