Rapid Construction of a Chloromethyl-Substituted Duocarmycin-like Prodrug.
1,2,3,6-tetrahydropyrrolo[3,2-e]indole
duocarmycin
prodrug
selective halogenation
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
16 Jun 2023
16 Jun 2023
Historique:
received:
25
05
2023
revised:
15
06
2023
accepted:
15
06
2023
medline:
29
6
2023
pubmed:
28
6
2023
entrez:
28
6
2023
Statut:
epublish
Résumé
The construction of duocarmycin-like compounds is often associated with lengthy synthetic routes. Presented herein is the development of a short and convenient synthesis of a type of duocarmycin prodrug. The 1,2,3,6-tetrahydropyrrolo[3,2-
Identifiants
pubmed: 37375372
pii: molecules28124818
doi: 10.3390/molecules28124818
pmc: PMC10304315
pii:
doi:
Substances chimiques
Duocarmycins
0
Prodrugs
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Références
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