The Brain/MINDS Marmoset Connectivity Resource: An open-access platform for cellular-level tracing and tractography in the primate brain.
Journal
PLoS biology
ISSN: 1545-7885
Titre abrégé: PLoS Biol
Pays: United States
ID NLM: 101183755
Informations de publication
Date de publication:
06 2023
06 2023
Historique:
received:
12
01
2023
accepted:
11
05
2023
revised:
12
07
2023
medline:
14
7
2023
pubmed:
29
6
2023
entrez:
29
6
2023
Statut:
epublish
Résumé
The primate brain has unique anatomical characteristics, which translate into advanced cognitive, sensory, and motor abilities. Thus, it is important that we gain insight on its structure to provide a solid basis for models that will clarify function. Here, we report on the implementation and features of the Brain/MINDS Marmoset Connectivity Resource (BMCR), a new open-access platform that provides access to high-resolution anterograde neuronal tracer data in the marmoset brain, integrated to retrograde tracer and tractography data. Unlike other existing image explorers, the BMCR allows visualization of data from different individuals and modalities in a common reference space. This feature, allied to an unprecedented high resolution, enables analyses of features such as reciprocity, directionality, and spatial segregation of connections. The present release of the BMCR focuses on the prefrontal cortex (PFC), a uniquely developed region of the primate brain that is linked to advanced cognition, including the results of 52 anterograde and 164 retrograde tracer injections in the cortex of the marmoset. Moreover, the inclusion of tractography data from diffusion MRI allows systematic analyses of this noninvasive modality against gold-standard cellular connectivity data, enabling detection of false positives and negatives, which provide a basis for future development of tractography. This paper introduces the BMCR image preprocessing pipeline and resources, which include new tools for exploring and reviewing the data.
Identifiants
pubmed: 37384809
doi: 10.1371/journal.pbio.3002158
pii: PBIOLOGY-D-23-00097
pmc: PMC10337976
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e3002158Informations de copyright
Copyright: © 2023 Skibbe et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Neuroimage. 2010 Dec;53(4):1233-43
pubmed: 20643215
Cereb Cortex. 2021 Nov 23;32(1):15-28
pubmed: 34274966
Annu Rev Neurosci. 2021 Jul 8;44:27-48
pubmed: 34236888
Neuroimage. 2018 Apr 1;169:106-116
pubmed: 29208569
Cell. 2014 Feb 27;156(5):1096-111
pubmed: 24581503
Neuron. 2016 Nov 2;92(3):582-590
pubmed: 27809998
Cereb Cortex. 2014 Jan;24(1):17-36
pubmed: 23010748
Nat Commun. 2020 Feb 28;11(1):1133
pubmed: 32111833
Neuron. 2022 Jan 5;110(1):16-20
pubmed: 34731649
Front Neuroinform. 2011 Jun 27;5:4
pubmed: 21743807
Neuroimage. 2021 Feb 1;226:117625
pubmed: 33301940
Front Neural Circuits. 2014 Sep 17;8:110
pubmed: 25278843
Proc Natl Acad Sci U S A. 2015 May 26;112(21):E2820-8
pubmed: 25964365
Front Neural Circuits. 2014 Aug 08;8:96
pubmed: 25152716
Neuron. 2015 May 6;86(3):617-31
pubmed: 25950631
Neuron. 2016 Apr 20;90(2):219-33
pubmed: 27100195
J Neurosci. 2016 Jun 22;36(25):6758-70
pubmed: 27335406
Front Neuroanat. 2015 May 20;9:61
pubmed: 26042001
Front Neuroinform. 2012 Dec 27;6:30
pubmed: 23293600
J Magn Reson Imaging. 2007 May;25(5):1051-8
pubmed: 17457801
Proc Natl Acad Sci U S A. 2021 Sep 14;118(37):
pubmed: 34493677
Neurosci Res. 2009 Feb;63(2):149-54
pubmed: 19028532
Cereb Cortex. 1991 Jan-Feb;1(1):1-47
pubmed: 1822724
Cereb Cortex. 2021 Nov 23;32(1):41-62
pubmed: 34255833
PLoS Biol. 2019 Mar 22;17(3):e2005346
pubmed: 30901324
Neuroimage. 2019 Apr 1;189:832-846
pubmed: 30711468
NMR Biomed. 2019 Apr;32(4):e3785
pubmed: 28945294
Magn Reson Med. 1999 Sep;42(3):515-25
pubmed: 10467296
Sci Data. 2023 Apr 27;10(1):221
pubmed: 37105968
J Comp Neurol. 2009 May 1;514(1):11-29
pubmed: 19260047
J Comp Neurol. 2016 Aug 1;524(11):2161-81
pubmed: 27099164
Nat Commun. 2017 Nov 7;8(1):1349
pubmed: 29116093
Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16574-9
pubmed: 25368179
Philos Trans R Soc Lond B Biol Sci. 2001 Aug 29;356(1412):1159-86
pubmed: 11545697
Nat Neurosci. 2020 Feb;23(2):271-280
pubmed: 31932765
Nat Methods. 2012 Jan 15;9(3):255-8
pubmed: 22245809
Proc Natl Acad Sci U S A. 2021 May 4;118(18):
pubmed: 33903237
Neuroimage. 2021 Feb 1;226:117620
pubmed: 33307224
Neuroimage. 2019 Nov 15;202:116137
pubmed: 31473352
Cereb Cortex. 2013 Aug;23(8):1901-22
pubmed: 22735155
Proc Natl Acad Sci U S A. 2020 Sep 1;117(35):21681-21689
pubmed: 32817555
Neuroimage. 2017 Nov 15;162:86-92
pubmed: 28830766
Neuroimage. 2011 Jan 15;54(2):955-62
pubmed: 20854913
Neuroimage. 2020 Nov 1;221:117201
pubmed: 32739552
Neuron. 2023 May 9;:
pubmed: 37196659
Nat Commun. 2021 Sep 15;12(1):5388
pubmed: 34526497
Neurosci Biobehav Rev. 2022 Jul;138:104692
pubmed: 35569579
Sci Data. 2018 Feb 13;5:180009
pubmed: 29437168
Neurosci Res. 2015 Apr;93:3-7
pubmed: 25264372
Philos Trans R Soc Lond B Biol Sci. 2015 May 19;370(1668):
pubmed: 25823872
Cell Rep. 2015 Dec 1;13(9):1989-99
pubmed: 26655910
PLoS One. 2012;7(10):e46371
pubmed: 23056291
Neuroimage. 2023 Apr 15;270:119999
pubmed: 36871795
Neurosci Res. 2015 Apr;93:144-57
pubmed: 25240284
Sci Rep. 2020 Dec 18;10(1):21285
pubmed: 33339834
Neuroimage. 2011 Feb 1;54(3):2033-44
pubmed: 20851191
Nature. 2014 Apr 10;508(7495):207-14
pubmed: 24695228
Comput Methods Programs Biomed. 2006 Feb;81(2):106-16
pubmed: 16413083
Methods. 2015 Feb;73:4-17
pubmed: 25536338
J Comp Neurol. 2014 Jan 1;522(1):225-59
pubmed: 23983048
Science. 2017 Oct 27;358(6362):478-482
pubmed: 29074767