Update on the treatment of cancer cachexia.

Humans Cachexia / drug therapy Quality of Life Anorexia / etiology Neoplasms / complications
anorexia cachexia cancer therapy malnutrition weight loss

Journal

Drug discovery today
ISSN: 1878-5832
Titre abrégé: Drug Discov Today
Pays: England
ID NLM: 9604391

Informations de publication

Date de publication:
09 2023
Historique:
received: 21 10 2022
revised: 09 06 2023
accepted: 21 06 2023
medline: 4 9 2023
pubmed: 30 6 2023
entrez: 29 6 2023
Statut: ppublish

Résumé

Cancer cachexia is a complex multifaceted syndrome involving functional impairment and changes in body composition that cannot be reversed by nutritional support. Cancer cachexia is characterized by decreased skeletal muscle mass, increased lipolysis, and decreased food intake. Cancer cachexia decreases chemotherapy tolerance as well as quality of life. However, because no fully effective interventions are available, cancer cachexia remains an unmet need in cancer treatment. In recent years, several discoveries and treatments for cancer cachexia have been studied, and guidelines have been published. We believe that the development of effective strategies for the diagnosis and treatment of cancer cachexia will lead to breakthroughs in cancer treatment.

Identifiants

DOI: 10.1016/j.drudis.2023.103689 PMID: 37385369
pubmed: 37385369
pii: S1359-6446(23)00205-2
doi: 10.1016/j.drudis.2023.103689
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

103689

Informations de copyright

Copyright © 2023 Elsevier Ltd. All rights reserved.

Auteurs

Kenichi Nishie (K)

Department of Respiratory Medicine, Iida Municipal Hospital, 438 Yawatamachi Iida Nagano, 395-0814, Japan; The First Department of Internal Medicine, Shinshu University School of Medicine, Japan. Electronic address: kennishie@imh.jp.

Tomomi Nishie (T)

The Faculty of Pharmaceutical Sciences, Ritsumeikan University, Japan.

Seiichi Sato (S)

Department of Pharmaceutics, Iida Municipal Hospital, Japan.

Masayuki Hanaoka (M)

The First Department of Internal Medicine, Shinshu University School of Medicine, Japan.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Update on the treatment of cancer cachexia.
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Cachexie › Update on the treatment of cancer cachexia.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Mesures épidémiologiques › Démographie › État de santé › Qualité de vie › Update on the treatment of cancer cachexia.
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Signes et symptômes digestifs › Anorexie › Update on the treatment of cancer cachexia.
questionsmedicales.fr › Tumeurs › Update on the treatment of cancer cachexia.