Skeletal muscle relaxants for the treatment of myofascial pelvic pain and high tone pelvic floor disorders.


Journal

Current opinion in obstetrics & gynecology
ISSN: 1473-656X
Titre abrégé: Curr Opin Obstet Gynecol
Pays: England
ID NLM: 9007264

Informations de publication

Date de publication:
01 08 2023
Historique:
medline: 3 7 2023
pubmed: 30 6 2023
entrez: 30 6 2023
Statut: ppublish

Résumé

Chronic pelvic main is a complex process that includes many causes. In gynecology, the treatment of myofascial pelvic pain and high tone pelvic floor disorders can be managed with skeletal muscle relaxants for select clinical indications. A review of skeletal muscle relaxants will be included for gynecologic indications. There are limited studies on vaginal skeletal muscle relaxants, but there can be oral forms used for chronic myofascial pelvic pain. They function as antispastic, antispasmodic, and combination of the two modes of action. Diazepam is the most studied for myofascial pelvic pain in both oral and vaginal formulations. Its use can be combined with multimodal management to optimize outcomes. Other medications have limitations due to dependency and limited studies that demonstrate improvement in pain scales. Skeletal muscle relaxants have limited high quality studies for chronic myofascial pelvic pain. Their use can be combined with multimodal options to improve clinical outcomes. Additional studies are needed for vaginal preparations and evaluation of safety and clinical efficacy for patient reported outcomes measures in patients living with chronic myofascial pelvic pain.

Identifiants

pubmed: 37387696
doi: 10.1097/GCO.0000000000000894
pii: 00001703-202308000-00007
doi:

Substances chimiques

Neuromuscular Agents 0

Types de publication

Review Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

311-315

Informations de copyright

Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.

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Auteurs

Virginia Flatow (V)

Division of Minimally Invasive Gynecologic Surgery, Department of Obstetrics, Gynecology and Reproductive Sciences, Mount Sinai Hospital at the Icahn School of Medicine, New York, New York.

Jean Uy-Kroh (J)

Division of Minimally Invasive Gynecologic Surgery, Department of Obstetrics and Gynecology, The Cleveland Clinic Cleveland, Ohio.

Erin T Carey (ET)

Division of Minimally Invasive Gynecologic Surgery, Department of Obstetrics and Gynecology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

Charles Ascher-Walsh (C)

Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics, Gynecology and Reproductive Sciences, Mount Sinai Hospital at the Icahn School of Medicine, New York, New York, USA.

Susan Khalil (S)

Division of Minimally Invasive Gynecologic Surgery, Department of Obstetrics, Gynecology and Reproductive Sciences, Mount Sinai Hospital at the Icahn School of Medicine, New York, New York.

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Classifications MeSH