Continuous Monitoring of the Hydration Behavior of Hydrophilic Matrix Tablets Using Time-Domain NMR.

Delayed-Action Preparations Polyethylene Glycols / chemistry Magnetic Resonance Spectroscopy Tablets Water Hypromellose Derivatives / chemistry Solubility Methylcellulose / chemistry
continuous monitoring extended drug release hydration hydrophilic matrix tablet time-domain NMR

Journal

Chemical & pharmaceutical bulletin
ISSN: 1347-5223
Titre abrégé: Chem Pharm Bull (Tokyo)
Pays: Japan
ID NLM: 0377775

Informations de publication

Date de publication:
2023
Historique:
medline: 4 7 2023
pubmed: 3 7 2023
entrez: 2 7 2023
Statut: ppublish

Résumé

Time-domain NMR (TD-NMR) was used for continuous monitoring of the hydration behavior of hydrophilic matrix tablets. The model matrix tablets comprised high molecular weight polyethylene oxide (PEO), hydroxypropyl methylcellulose (HPMC), and polyethylene glycol (PEG). The model tablets were immersed in water. Their T

Identifiants

DOI: 10.1248/cpb.c23-00214 PMID: 37394606
pubmed: 37394606
doi: 10.1248/cpb.c23-00214
doi:

Substances chimiques

Delayed-Action Preparations 0
Polyethylene Glycols 3WJQ0SDW1A
Tablets 0
Water 059QF0KO0R
Hypromellose Derivatives 3NXW29V3WO
Methylcellulose 9004-67-5

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

576-583

Auteurs

Takahiro Tsuji (T)

Formulation Development Department, Development & Planning Division, Nichi-Iko Pharmaceutical Co., Ltd.

Takashi Ono (T)

Formulation Development Department, Development & Planning Division, Nichi-Iko Pharmaceutical Co., Ltd.
Laboratory of Pharmaceutical Technology, School of Pharmacy and Pharmaceutical Sciences, University of Toyama.

Hiromu Taguchi (H)

Laboratory of Pharmaceutical Technology, School of Pharmacy and Pharmaceutical Sciences, University of Toyama.

Kok Hoong Leong (KH)

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Malaya.

Yoshihiro Hayashi (Y)

Formulation Development Department, Development & Planning Division, Nichi-Iko Pharmaceutical Co., Ltd.

Shungo Kumada (S)

Formulation Development Department, Development & Planning Division, Nichi-Iko Pharmaceutical Co., Ltd.

Kotaro Okada (K)

Laboratory of Pharmaceutical Technology, School of Pharmacy and Pharmaceutical Sciences, University of Toyama.

Yoshinori Onuki (Y)

Laboratory of Pharmaceutical Technology, School of Pharmacy and Pharmaceutical Sciences, University of Toyama.

Articles similaires

Effects of water-insoluble wheat bran-fraction powder on disease activity and caecal microbiota in dextran sodium sulphate-induced inflammatory bowel disease mouse model.

Kazuya Koga, Mizuki Sato, Nanase Okamoto et al.
1.00
Animals Dietary Fiber Dextran Sulfate Mice Disease Models, Animal

Study on the mechanical properties of granite responses of cyclic heating and water cooling considering microcosmic and energy.

Xiaokang Liang, Hanxiang Liu, Yong Yuan et al.
1.00
Silicon Dioxide Water Hot Temperature Compressive Strength X-Ray Diffraction

Rice growth and yield responses to saline water irrigation are related to Na+/K+ ratio in plants.

Priya Lal Chandra Paul, Afsana Jahan, Palash Kumar Kundu et al.
1.00
Oryza Agricultural Irrigation Potassium Sodium Soil

Drug repurposing against fucosyltransferase-2 via docking, STD-NMR, and molecular dynamic simulation studies.

Muhammad Atif, Humaira Zafar, Atia-Tul- Wahab et al.
1.00
Fucosyltransferases Drug Repositioning Molecular Docking Simulation Molecular Dynamics Simulation Humans

Classifications MeSH

questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Systèmes de délivrance de médicaments › Préparations à action retardée › Continuous Monitoring of the Hydration...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Polymères › Polyéthylène glycols › Continuous Monitoring of the Hydration...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectroscopie par résonance magnétique › Continuous Monitoring of the Hydration...
questionsmedicales.fr › Préparations pharmaceutiques › Comprimés › Continuous Monitoring of the Hydration...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Oxydes › Eau › Continuous Monitoring of the Hydration...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Polymères › Biopolymères › Cellulose › Dérivés de l'hypromellose › Continuous Monitoring of the Hydration...
questionsmedicales.fr › Phénomènes chimiques › Solubilité › Continuous Monitoring of the Hydration...
questionsmedicales.fr › Glucides › Polyosides › Glucanes › Méthylcellulose › Continuous Monitoring of the Hydration...