CSF Aβ

Humans Middle Aged Aged Apolipoprotein E4 / genetics Amyloid beta-Peptides / cerebrospinal fluid Alzheimer Disease / diagnostic imaging tau Proteins / cerebrospinal fluid Heterozygote Biomarkers / cerebrospinal fluid
Alzheimer’s disease Amyloid Apolipoprotein E Cognition Phosphorylated tau

Journal

Neurobiology of aging
ISSN: 1558-1497
Titre abrégé: Neurobiol Aging
Pays: United States
ID NLM: 8100437

Informations de publication

Date de publication:
09 2023
Historique:
received: 16 02 2023
revised: 09 05 2023
accepted: 10 05 2023
medline: 18 7 2023
pubmed: 4 7 2023
entrez: 3 7 2023
Statut: ppublish

Résumé

This study aimed to determine the relationship between the apolipoprotein E (APOE) ε4 allele and cerebrospinal fluid (CSF) and neuroimaging biomarkers of Alzheimer's disease, and cognition in cognitively unimpaired (CU) middle-aged adults (n = 82; M

Identifiants

DOI: 10.1016/j.neurobiolaging.2023.05.009 PMID: 37399739
pubmed: 37399739
pii: S0197-4580(23)00101-X
doi: 10.1016/j.neurobiolaging.2023.05.009
pii:
doi:

Substances chimiques

Apolipoprotein E4 0
Amyloid beta-Peptides 0
tau Proteins 0
Biomarkers 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

209-218

Subventions

Organisme : NIA NIH HHS
ID : K99 AG061238
Pays : United States

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest Y.Y. Lim, N. Yassi, L. Bransby, S. Ayton, R.F. Buckley, D. Eratne, D. Velakoulis, Q.X. Li, C. Fowler, and C.L. Masters have no relevant conflicts of interest to disclose. Paul Maruff is a full-time employee of Cogstate Ltd.

Auteurs

Yen Ying Lim (YY)

Turner Institute of Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, Australia. Electronic address: yenying.lim@monash.edu.

Nawaf Yassi (N)

Population Health and Immunity Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Australia; Department of Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, Australia.

Lisa Bransby (L)

Turner Institute of Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, Australia.

Scott Ayton (S)

Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Australia.

Rachel F Buckley (RF)

Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.

Dhamidhu Eratne (D)

Melbourne Neuropsychiatry Centre, University of Melbourne, Parkville, Australia.

Dennis Velakoulis (D)

Melbourne Neuropsychiatry Centre, University of Melbourne, Parkville, Australia.

Qiao-Xin Li (QX)

Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Australia.

Christopher Fowler (C)

Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Australia.

Colin L Masters (CL)

Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Australia.

Paul Maruff (P)

Turner Institute of Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, Australia; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Australia; Cogstate Ltd., Melbourne, Australia.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › CSF Aβ
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › CSF Aβ
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › CSF Aβ
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Lipoprotéines › Apolipoprotéines › Apolipoprotéines E › Apolipoprotéine E4 › CSF Aβ
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Peptides bêta-amyloïdes › CSF Aβ
questionsmedicales.fr › Troubles mentaux › Troubles neurocognitifs › Démence › Maladie d'Alzheimer › CSF Aβ
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de tissu nerveux › Protéines associées aux microtubules › Protéines tau › CSF Aβ
questionsmedicales.fr › Phénomènes génétiques › Génotype › Hétérozygote › CSF Aβ
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › CSF Aβ