Late Diagnosis in the Era of Universal Newborn Screening Negatively Affects Short- and Long-Term Growth and Health Outcomes in Infants with Cystic Fibrosis.
CFTR variants
newborn screening programs
sweat test
Journal
The Journal of pediatrics
ISSN: 1097-6833
Titre abrégé: J Pediatr
Pays: United States
ID NLM: 0375410
Informations de publication
Date de publication:
11 2023
11 2023
Historique:
received:
24
04
2023
revised:
19
06
2023
accepted:
26
06
2023
medline:
13
11
2023
pubmed:
6
7
2023
entrez:
5
7
2023
Statut:
ppublish
Résumé
Newborn screening for cystic fibrosis was fully implemented in the US by 2010, but delays in timeliness of evaluation for infants with positive newborn screening tests persist. Through evaluation of national patient registry data, we determined that late initiation of cystic fibrosis care is associated with poorer long-term nutritional outcomes.
Identifiants
pubmed: 37406853
pii: S0022-3476(23)00458-4
doi: 10.1016/j.jpeds.2023.113595
pii:
doi:
Substances chimiques
Cystic Fibrosis Transmembrane Conductance Regulator
126880-72-6
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
113595Informations de copyright
Copyright © 2023 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest A.E. and R.W. are employees of the Cystic Fibrosis Foundation. Supported by the Cystic Fibrosis Foundation (MCCOLL19QI0). The other authors declare no conflicts of interest.