Systemic capillary leak syndrome secondary to decompression sickness.


Journal

BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291

Informations de publication

Date de publication:
05 Jul 2023
Historique:
pmc-release: 05 07 2025
medline: 7 7 2023
pubmed: 6 7 2023
entrez: 5 7 2023
Statut: epublish

Résumé

Systemic capillary leak syndrome is a rare derangement of endothelial function characterised by extravasation of plasma and proteins into the interstitial space. Primary capillary leak syndrome is a rare, episodic medical illness of unknown molecular pathology while secondary capillary leak syndrome may be precipitated by any number of inflammatory and infectious syndromes. Decompression sickness, a disorder of depressurisation, has been identified as a very rare trigger. We present a structured case report of systemic capillary leak syndrome secondary to decompression sickness following deep diving, informing physicians of this potential complication. No pharmacological therapy has substantial evidence in the treatment of acute systemic capillary leak syndrome. By review of current recommendations for acute management, we also emphasise an observed positive response to judicious fluid resuscitation and an oral cyclic AMP-elevating agent (ie, terbutaline).

Identifiants

pubmed: 37407231
pii: 16/7/e253045
doi: 10.1136/bcr-2022-253045
pmc: PMC10335547
pii:
doi:

Substances chimiques

Terbutaline N8ONU3L3PG

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© BMJ Publishing Group Limited 2023. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Auteurs

Akshay Mathavan (A)

Internal Medicine, University of Florida, Gainesville, Florida, USA amathavan1996@ufl.edu.

Akash Mathavan (A)

Internal Medicine, University of Florida, Gainesville, Florida, USA.

Kirk Jones (K)

Internal Medicine, University of Florida, Gainesville, Florida, USA.

Ali Ataya (A)

Division of Pulmonary, Critical Care and Sleep Medicine, University of Florida, Gainesville, Florida, USA.

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Classifications MeSH