Does a corticosteroid injection plus exercise or exercise alone add to the effect of patient advice and a heel cup for patients with plantar fasciopathy? A randomised clinical trial.


Journal

British journal of sports medicine
ISSN: 1473-0480
Titre abrégé: Br J Sports Med
Pays: England
ID NLM: 0432520

Informations de publication

Date de publication:
Sep 2023
Historique:
accepted: 20 06 2023
medline: 2 10 2023
pubmed: 7 7 2023
entrez: 6 7 2023
Statut: ppublish

Résumé

To compare the effectiveness of patient advice plus heel cup alone (PA) versus PA and lower limb exercise (PAX) versus PAX plus corticosteroid injection (PAXI) to improve self-reported pain in patients with plantar fasciopathy. We recruited 180 adults with plantar fasciopathy confirmed by ultrasonography for this prospectively registered three-armed, randomised, single-blinded superiority trial. Patients were randomly allocated to PA (n=62), PA plus self-dosed lower limb heavy-slow resistance training consisting of heel raises (PAX) (n=59), or PAX plus an ultrasound-guided injection of 1 mL triamcinolone 20 mg/mL (PAXI) (n=59). The primary outcome was changed in the pain domain of the Foot Health Status Questionnaire (ranging from 0 'worst' to 100 'best') from baseline to the 12-week follow-up. The minimal important difference in the pain domain is 14.1 points. The outcome was collected at baseline and at 4, 12, 26, and 52 weeks. The primary analysis found a statistically significant difference between PA and PAXI after 12 weeks favouring PAXI (adjusted mean difference: -9.1 (95% CI -16.8 to -1.3; p=0.023)) and over 52 weeks (adjusted mean difference: -5.2 (95% CI -10.4 to -0.1; p=0.045)). At no follow-up did the mean difference between groups exceed the pre-specified minimal important difference. No statistically significant difference was found between PAX and PAXI or between PA and PAX at any time. No clinically relevant between-group differences were found after 12 weeks. The results indicate that combining a corticosteroid injection with exercise is not superior to exercise or no exercise. NCT03804008.

Identifiants

pubmed: 37414460
pii: bjsports-2023-106948
doi: 10.1136/bjsports-2023-106948
pmc: PMC10579183
doi:

Substances chimiques

Adrenal Cortex Hormones 0

Banques de données

ClinicalTrials.gov
['NCT03804008']

Types de publication

Randomized Controlled Trial Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1180-1186

Informations de copyright

© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

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Auteurs

Henrik Riel (H)

Center for General Practice at Aalborg University, Aalborg University, Aalborg, Denmark hriel@dcm.aau.dk.

Bill Vicenzino (B)

The University of Queensland School of Health and Rehabilitation Sciences: Physiotherapy: Sports Injury Rehabilitation and Prevention for Health, The University of Queensland, Brisbane, Queensland, Australia.

Jens Lykkegaard Olesen (JL)

Center for General Practice at Aalborg University, Aalborg University, Aalborg, Denmark.

Martin Bach Jensen (M)

Center for General Practice at Aalborg University, Aalborg University, Aalborg, Denmark.

Lars Holger Ehlers (LH)

Nordic Institute of Health Economics, Aarhus, Denmark.

Michael Skovdal Rathleff (MS)

Center for General Practice at Aalborg University, Aalborg University, Aalborg, Denmark.
Department of Health Science and Technology, Aalborg University, Aalborg, Denmark.
Department of Occupational Therapy and Physiotherapy, Aalborg University Hospital, Aalborg, Denmark.

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