Acupuncture on GB34 for immediate analgesia and regulating pain-related anxiety for patients with biliary colic: a protocol of randomized controlled trial.
Acupuncture
Biliary colic
Protocol
Randomized controlled trial
Journal
BMC complementary medicine and therapies
ISSN: 2662-7671
Titre abrégé: BMC Complement Med Ther
Pays: England
ID NLM: 101761232
Informations de publication
Date de publication:
07 Jul 2023
07 Jul 2023
Historique:
received:
11
05
2023
accepted:
09
06
2023
medline:
10
7
2023
pubmed:
8
7
2023
entrez:
7
7
2023
Statut:
epublish
Résumé
Biliary colic (BC) is a frequent hepatobiliary disorder encountered in emergency departments. Acupuncture may be effective as an alternative and complementary medicine for BC. Nonetheless, rigorous trials investigating its efficacy are lacking. Therefore, the aim of this study protocol is to determine whether acupuncture provides immediate relief of pain and associated symptoms in BC patients. Eighty-six participants who aged from 18 to 60 years with BC will be recruited in the First People's Hospital of Longquanyi District, Chengdu (West China Longquan Hospital Sichuan University). All participants will be allocated into two treatment groups including acupuncture group and sham acupuncture group using a 1:1 ratio. Each group will only receive a single 30-min needle treatment while waiting for their test results after completing the routine examination for BC. The primary outcome of the study is to assess the change in pain intensity after the 30-min acupuncture treatment. The secondary outcomes of the study include the change in pain intensity at various time points, the degree of gastrointestinal symptoms at different time points, the level of anxiety experienced during pain episodes at different time points, the score of Pain Anxiety Symptoms Scale-20 (PASS-20), the score of Fear of Pain Questionnaire-III (FPQ-III), and the score of Pain Catastrophizing Scale (PCS), among others. The results of this research will provide substantial evidence regarding the efficacy of acupuncture in alleviating symptoms associated with BC. ClinicalTrials.gov, ChiCTR2300070661. Registered on 19 April 2023.
Sections du résumé
BACKGROUND
BACKGROUND
Biliary colic (BC) is a frequent hepatobiliary disorder encountered in emergency departments. Acupuncture may be effective as an alternative and complementary medicine for BC. Nonetheless, rigorous trials investigating its efficacy are lacking. Therefore, the aim of this study protocol is to determine whether acupuncture provides immediate relief of pain and associated symptoms in BC patients.
METHOD
METHODS
Eighty-six participants who aged from 18 to 60 years with BC will be recruited in the First People's Hospital of Longquanyi District, Chengdu (West China Longquan Hospital Sichuan University). All participants will be allocated into two treatment groups including acupuncture group and sham acupuncture group using a 1:1 ratio. Each group will only receive a single 30-min needle treatment while waiting for their test results after completing the routine examination for BC. The primary outcome of the study is to assess the change in pain intensity after the 30-min acupuncture treatment. The secondary outcomes of the study include the change in pain intensity at various time points, the degree of gastrointestinal symptoms at different time points, the level of anxiety experienced during pain episodes at different time points, the score of Pain Anxiety Symptoms Scale-20 (PASS-20), the score of Fear of Pain Questionnaire-III (FPQ-III), and the score of Pain Catastrophizing Scale (PCS), among others.
DISCUSSION
CONCLUSIONS
The results of this research will provide substantial evidence regarding the efficacy of acupuncture in alleviating symptoms associated with BC.
TRIAL REGISTRATION
BACKGROUND
ClinicalTrials.gov, ChiCTR2300070661. Registered on 19 April 2023.
Identifiants
pubmed: 37420212
doi: 10.1186/s12906-023-04030-8
pii: 10.1186/s12906-023-04030-8
pmc: PMC10327363
doi:
Types de publication
Clinical Trial Protocol
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
224Subventions
Organisme : National Natural Science Foundation of China for the Youth
ID : No. 81904096
Organisme : Special Project of Central Government Guides Local Science and Technology Development' in Sichuan Provincial Department of Science and Technology
ID : 2020ZYD046
Organisme : China Postdoctoral Science Foundation
ID : No. 2019M653361
Informations de copyright
© 2023. The Author(s).
Références
Int J Surg. 2010;8(1):15-7
pubmed: 19857610
J Hepatol. 2016 Jul;65(1):146-181
pubmed: 27085810
Am J Med. 1999 Dec 13;107(6A):3S-8S; discussion 8S-10S
pubmed: 10628588
Brain. 2021 Mar 3;144(2):665-681
pubmed: 33367648
JA Clin Rep. 2020 Apr 8;6(1):26
pubmed: 32270308
Int J Surg Case Rep. 2021 Jun;83:105950
pubmed: 33989874
J Behav Med. 1998 Aug;21(4):389-410
pubmed: 9789168
Dtsch Arztebl Int. 2020 Feb 28;117(9):148-158
pubmed: 32234195
J Urol. 2018 Oct;200(4):815-822
pubmed: 29733836
Pain Res Manag. 2002 Spring;7(1):45-50
pubmed: 16231066
Ann Emerg Med. 2014 Nov;64(5):526-532.e1
pubmed: 24818542
Altern Ther Health Med. 2010 Nov-Dec;16(6):22-7
pubmed: 21280459
Ann Intern Med. 2021 Oct;174(10):1357-1366
pubmed: 34399062
Int J Nurs Stud. 2005 Jul;42(5):521-30
pubmed: 15921983
Acupunct Med. 2012 Sep;30(3):214-21
pubmed: 22617434
Cardiol Rev. 2010 Jul-Aug;18(4):204-12
pubmed: 20539104
Nurs Stand. 1993 Mar 17-23;7(26):40-2
pubmed: 8481316
J Urol. 2003 Sep;170(3):741-4
pubmed: 12913687
BMJ Open. 2022 Jan 13;12(1):e050413
pubmed: 35027415
Leg Med (Tokyo). 2006 May;8(3):194-7
pubmed: 16413812
Am J Gastroenterol. 2012 Aug;107(8):1236-47
pubmed: 22641307
Nat Rev Dis Primers. 2016 Apr 28;2:16024
pubmed: 27121416
Acupunct Med. 2002 Dec;20(4):168-74
pubmed: 12512790
J Pain. 2017 Sep;18(9):1139-1149
pubmed: 28528981
Br J Anaesth. 2019 Sep;123(3):266-268
pubmed: 31326087
Neural Plast. 2015;2015:504691
pubmed: 25810926
BMJ. 2013 Jan 08;346:e7586
pubmed: 23303884
JAMA. 2014 Oct 1;312(13):1313-22
pubmed: 25268438
J Altern Complement Med. 2009 Mar;15(3):213-6
pubmed: 19250001
Postgrad Med. 2019 Sep;131(7):438-444
pubmed: 31482756
Int J Surg. 2014;12(2):169-76
pubmed: 24342080
Pain Med. 2016 Jun;17(6):1069-78
pubmed: 26814269
Complement Ther Med. 2003 Dec;11(4):235-42
pubmed: 15022656
Sci Rep. 2021 Jan 12;11(1):577
pubmed: 33436778
J Gastrointest Surg. 2021 Mar;25(3):713-719
pubmed: 32935270
Am J Emerg Med. 2016 Nov;34(11):2112-2116
pubmed: 27475042
JAMA. 2018 Oct 16;320(15):1612
pubmed: 30326127
Complement Ther Med. 2011 Jan;19 Suppl 1:S41-8
pubmed: 21195294
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2013 Jun;33(6):761-5
pubmed: 23980354