Effects of a Pirin-like protein on strain growth and spinosad biosynthesis in Saccharopolyspora spinosa.
Growth development
Pirin-like protein
Saccharopolyspora spinosa
Spinosad
Journal
Applied microbiology and biotechnology
ISSN: 1432-0614
Titre abrégé: Appl Microbiol Biotechnol
Pays: Germany
ID NLM: 8406612
Informations de publication
Date de publication:
Sep 2023
Sep 2023
Historique:
received:
26
03
2023
accepted:
11
06
2023
revised:
01
06
2023
medline:
23
10
2023
pubmed:
10
7
2023
entrez:
10
7
2023
Statut:
ppublish
Résumé
Pirin family proteins perform a variety of biological functions and widely exist in all living organisms. A few studies have shown that Pirin family proteins may be involved in the biosynthesis of antibiotics in actinomycetes. However, the function of Pirin-like proteins in S. spinosa is still unclear. In this study, the inactivation of the sspirin gene led to serious growth defects and the accumulation of H
Identifiants
pubmed: 37428187
doi: 10.1007/s00253-023-12636-8
pii: 10.1007/s00253-023-12636-8
doi:
Substances chimiques
spinosad
XPA88EAP6V
Hydrogen Peroxide
BBX060AN9V
Macrolides
0
Drug Combinations
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
5439-5451Subventions
Organisme : National Natural Science Foundation of China
ID : 31770106
Organisme : Natural Science Foundation of Hunan Province
ID : 2021JJ40341
Informations de copyright
© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
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