Effect of topical antibiotics on the prevention and management of wound infections: A meta-analysis.
antiseptic
topical antibiotic
uncomplicated wounds
wound infection
Journal
International wound journal
ISSN: 1742-481X
Titre abrégé: Int Wound J
Pays: England
ID NLM: 101230907
Informations de publication
Date de publication:
Dec 2023
Dec 2023
Historique:
revised:
16
06
2023
received:
13
06
2023
accepted:
17
06
2023
medline:
29
11
2023
pubmed:
11
7
2023
entrez:
10
7
2023
Statut:
ppublish
Résumé
A meta-analysis research was implemented to appraise the effect of topical antibiotics (TAs) on the prevention and management of wound infections (WIs). Inclusive literature research was performed until April 2023, and 765 interconnected researches were reviewed. The 11 selected researches included 6500 persons with uncomplicated wounds at the starting point of the research: 2724 of them were utilising TAs, 3318 were utilising placebo and 458 were utilising antiseptics. Odds ratio (OR) and 95% confidence intervals (CIs) were utilised to appraise the consequence of TAs on the prevention and management of WIs by the dichotomous approach and a fixed or random model. TAs had significantly lower WI compared with placebo (OR, 0.59; 95% CI, 0.38-0.92, p = 0.02) and compared with antiseptics (OR, 0.52; 95% CI, 0.31-0.88, p = 0.01) in persons with uncomplicated wounds (UWs). TAs had significantly lower WIs compared with placebo and antiseptics in persons with UWs. However, caution needs to be taken when interacting with their values because of the low sample size of some of the chosen researches and low number of researches found for the comparisons in the meta-analysis.
Identifiants
pubmed: 37429583
doi: 10.1111/iwj.14290
pmc: PMC10681525
doi:
Substances chimiques
Anti-Bacterial Agents
0
Anti-Infective Agents, Local
0
Types de publication
Meta-Analysis
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
4015-4022Informations de copyright
© 2023 The Authors. International Wound Journal published by Medicalhelplines.com Inc and John Wiley & Sons Ltd.
Références
J Dermatolog Treat. 2015 Apr;26(2):151-8
pubmed: 24646178
Adv Drug Deliv Rev. 2006 Nov 15;58(11):1131-5
pubmed: 17097758
JAMA. 1996 Sep 25;276(12):972-7
pubmed: 8805732
BJS Open. 2021 Nov 9;5(6):
pubmed: 35038328
JAMA Surg. 2017 Aug 01;152(8):784-791
pubmed: 28467526
Cureus. 2023 Feb 26;15(2):e35493
pubmed: 37007356
Surgeon. 2022 Jun;20(3):e26-e35
pubmed: 33888427
BMJ. 2009 Jan 15;338:a2812
pubmed: 19147639
Heart Lung. 2017 Nov - Dec;46(6):464-467
pubmed: 28882385
Surg Endosc. 2021 Dec;35(12):6397-6412
pubmed: 34370122
Facial Plast Surg Aesthet Med. 2021 May-Jun;23(3):205-223
pubmed: 32721241
BMC Surg. 2018 Nov 19;18(1):102
pubmed: 30453917
Br J Surg. 2017 Aug;104(9):1123-1130
pubmed: 28656693
Int Wound J. 2023 Dec;20(10):4015-4022
pubmed: 37429583
Br J Surg. 2006 Aug;93(8):937-43
pubmed: 16779878
J Wound Care. 2022 May 2;31(5):394-397
pubmed: 35579312
Acad Emerg Med. 1995 Jan;2(1):4-10
pubmed: 7606610
Pacing Clin Electrophysiol. 2014 Mar;37(3):304-11
pubmed: 24164587
J Am Acad Dermatol. 1985 Aug;13(2 Pt 1):207-12
pubmed: 2995463
Musculoskelet Surg. 2018 Apr;102(1):35-39
pubmed: 28699136
Ophthalmology. 2020 Dec;127(12):1747-1754
pubmed: 32698033
J Arthroplasty. 2019 Aug;34(8):1815-1822
pubmed: 31005433
J Eur Acad Dermatol Venereol. 2011 Feb;25(2):130-7
pubmed: 20626534
J Arthroplasty. 2022 Jul;37(7):1405-1415.e1
pubmed: 35314283
Ann Pharmacother. 1997 May;31(5):559-63
pubmed: 9161648
Oncologist. 2016 Aug;21(8):931-9
pubmed: 27401897
Surv Ophthalmol. 2020 May - Jun;65(3):323-347
pubmed: 31838049
Nepal Med Coll J. 2009 Sep;11(3):189-91
pubmed: 20334068
Expert Rev Anti Infect Ther. 2009 Oct;7(8):957-65
pubmed: 19803705
J Viral Hepat. 2018 Jul;25(7):771-778
pubmed: 29377464
J Clin Epidemiol. 2009 Oct;62(10):e1-34
pubmed: 19631507
JAMA. 2000 Apr 19;283(15):2008-12
pubmed: 10789670
Adv Ther. 2018 Jul;35(7):1049-1058
pubmed: 29949044
Ann Emerg Med. 2013 Jan;61(1):86-8
pubmed: 22964473
Vaccine. 2020 Jul 31;38(35):5564-5568
pubmed: 32654907
JAMA Facial Plast Surg. 2019 Dec 01;21(6):491-497
pubmed: 31647506
Dermatol Surg. 2005 Jun;31(6):664-9
pubmed: 15996417
Respir Care. 2018 Nov;63(11):1370-1378
pubmed: 30108135
Eur J Pharm Sci. 2017 Jan 15;97:182-191
pubmed: 27866986
Exp Lung Res. 2020 Sep;46(7):258-269
pubmed: 32614625
Injury. 2005 Jun;36(6):783-7
pubmed: 15910834
BMJ. 2003 Sep 6;327(7414):557-60
pubmed: 12958120