Metabolic Dysregulation Explains the Diverse Impacts of Obesity in Males and Females with Gastrointestinal Cancers.

Male Female Humans Kynurenine Tryptophan Leukocytes, Mononuclear Obesity / genetics Gastrointestinal Neoplasms / genetics Adenocarcinoma
cancer gender disparity immunity metabolism obesity omics

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
29 Jun 2023
Historique:
received: 18 05 2023
revised: 09 06 2023
accepted: 24 06 2023
medline: 17 7 2023
pubmed: 14 7 2023
entrez: 14 7 2023
Statut: epublish

Résumé

The prevalence of obesity, defined as the body mass index (BMI) ≥ 30 kg/m

Identifiants

DOI: 10.3390/ijms241310847 PMID: 37446025 PMC: PMC10342094
pubmed: 37446025
pii: ijms241310847
doi: 10.3390/ijms241310847
pmc: PMC10342094
pii:
doi:

Substances chimiques

Kynurenine 343-65-7
Tryptophan 8DUH1N11BX

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : This work was supported by the IOTN: Data Management and Resource-Sharing Center (U24CA232979, S.R.R.), the TREC Fellowship Training Workshop (R25CA203650 (PI: Melinda Irwin); S.R.R.).
ID : n/a

Références

Methods Mol Biol. 2009;563:219-39
pubmed: 19597788
Semin Cancer Biol. 2022 Nov;86(Pt 3):542-565
pubmed: 35151845
Cancer Metab. 2022 Oct 26;10(1):17
pubmed: 36289552
SAGE Open Med. 2020 Apr 28;8:2050312120918265
pubmed: 32435480
Lancet. 2014 Aug 30;384(9945):766-81
pubmed: 24880830
Ann Acad Med Singap. 2009 Jan;38(1):57-9
pubmed: 19221672
Nat Med. 2019 Jan;25(1):141-151
pubmed: 30420753
Nat Commun. 2018 Dec 14;9(1):5330
pubmed: 30552315
Endocr Relat Cancer. 2011 Jun 08;18(3):371-84
pubmed: 21490239
Front Endocrinol (Lausanne). 2011 Sep 27;2:32
pubmed: 22654802
Am J Clin Nutr. 2014 May;99(5):999-1005
pubmed: 24572565
J Hematol Oncol. 2021 Nov 6;14(1):187
pubmed: 34742349
JAMA. 2003 Jan 1;289(1):76-9
pubmed: 12503980
Cell. 2020 Dec 23;183(7):1848-1866.e26
pubmed: 33301708
Front Oncol. 2020 Dec 09;10:607909
pubmed: 33363037
Cell. 2010 Apr 2;141(1):39-51
pubmed: 20371344
Adv Nutr. 2012 Jul 01;3(4):491-8
pubmed: 22797984
J Immunother Cancer. 2019 Mar 29;7(1):89
pubmed: 30922394
Int J Obes (Lond). 2016 Dec;40(12):1817-1822
pubmed: 27686524
Biochim Biophys Acta. 2010 Mar;1801(3):246-51
pubmed: 19818872
Front Immunol. 2016 Jan 05;6:637
pubmed: 26779183
Genome Biol. 2014;15(12):550
pubmed: 25516281
Bioinformatics. 2011 Jun 15;27(12):1739-40
pubmed: 21546393
Biol Sex Differ. 2020 Jul 23;11(1):43
pubmed: 32703269
Nat Rev Drug Discov. 2022 Feb;21(2):141-162
pubmed: 34862480
BMC Obes. 2016 Apr 29;3:22
pubmed: 27148454
Nucleic Acids Res. 2015 Apr 20;43(7):e47
pubmed: 25605792
Int J Obes (Lond). 2008 Sep;32(9):1431-7
pubmed: 18607383
N Engl J Med. 2016 Aug 25;375(8):794-8
pubmed: 27557308
Cold Spring Harb Mol Case Stud. 2015 Oct;1(1):a000588
pubmed: 27148576
Cancers (Basel). 2022 Apr 06;14(7):
pubmed: 35406621
Front Immunol. 2019 Aug 14;10:1940
pubmed: 31475003
Gut. 2018 Oct;67(10):1855-1863
pubmed: 28754779
Lancet Oncol. 2018 Mar;19(3):310-322
pubmed: 29449192
Nucleic Acids Res. 2018 Jan 4;46(D1):D661-D667
pubmed: 29136241
Molecules. 2019 Sep 04;24(18):
pubmed: 31487832
Front Genet. 2016 Sep 20;7:168
pubmed: 27703473

Auteurs

Spencer R Rosario (SR)

Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
ORCID: 0000-0002-2626-9257

Bowen Dong (B)

Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.

Yali Zhang (Y)

Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.

Hua-Hsin Hsiao (HH)

Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.

Emily Isenhart (E)

Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.

Jianmin Wang (J)

Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.

Erin M Siegel (EM)

Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA.
ORCID: 0000-0003-1779-2510

Arta M Monjazeb (AM)

Department of Radiation Oncology, University of California Davis, Sacramento, CA 95616, USA.

Dwight H Owen (DH)

Department of Medical Oncology, Ohio State University Comprehensive Cancer Center, Columbus, OH 43210, USA.

Prasenjit Dey (P)

Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.

Fred K Tabung (FK)

Department of Epidemiology, Ohio State University Comprehensive Cancer Center, Columbus, OH 43210, USA.
ORCID: 0000-0001-8193-7150

Daniel J Spakowicz (DJ)

Department of Medical Oncology, Ohio State University Comprehensive Cancer Center, Columbus, OH 43210, USA.
ORCID: 0000-0003-2314-6435

William J Murphy (WJ)

Department of Immunology, University of California Davis, Sacramento, CA 95616, USA.

Stephen Edge (S)

Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.

Sai Yendamuri (S)

Department of Thoracic Surgery, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.

Sami Ibrahimi (S)

Department of Medicine, Oklahoma University Health Stephenson Cancer Center, Oklahoma City, OK 73104, USA.

Jill M Kolesar (JM)

Department of Pharmacy, University of Kentucky College of Pharmacy, Lexington, KY 40506, USA.
ORCID: 0000-0003-1802-6439

Patsy H McDonald (PH)

Department of Cancer Biology, Moffitt Cancer Center, Tampa, FL 33612, USA.

Deepak Vadehra (D)

Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.

Michelle Churchman (M)

Precision Therapy and Diagnostics, Aster Insights, Hudson, FL 34667, USA.

Song Liu (S)

Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.

Pawel Kalinski (P)

Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.

Sarbajit Mukherjee (S)

Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Metabolic Dysregulation Explains the Diverse...
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Cynurénine › Metabolic Dysregulation Explains the Diverse...
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Acides aminés essentiels › Tryptophane › Metabolic Dysregulation Explains the Diverse...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Metabolic Dysregulation Explains the Diverse...
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Obésité › Metabolic Dysregulation Explains the Diverse...
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies gastro-intestinales › Tumeurs gastro-intestinales › Metabolic Dysregulation Explains the Diverse...
questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Tumeurs épithéliales épidermoïdes et glandulaires › Carcinomes › Adénocarcinome › Metabolic Dysregulation Explains the Diverse...