Statistical Modelling Investigation of MALDI-MSI-Based Approaches for Document Examination.


Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
04 Jul 2023
Historique:
received: 05 05 2023
revised: 21 06 2023
accepted: 30 06 2023
medline: 17 7 2023
pubmed: 14 7 2023
entrez: 14 7 2023
Statut: epublish

Résumé

Questioned document examination aims to assess if a document of interest has been forged. Spectroscopy-based methods are the gold standard for this type of evaluation. In the past 15 years, Matrix-Assisted Laser Desorption Ionisation-Mass Spectrometry Imaging (MALDI-MSI) has emerged as a powerful analytical tool for the examination of finger marks, blood, and hair. Therefore, this study intended to explore the possibility of expanding the forensic versatility of this technique through its application to questioned documents. Specifically, a combination of MALDI-MSI and chemometric approaches was investigated for the differentiation of seven gel pens, through their ink composition, over 44 days to assess:

Identifiants

pubmed: 37446869
pii: molecules28135207
doi: 10.3390/molecules28135207
pmc: PMC10343405
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : AUFF NOVA
ID : AUFF-E-2019-9-6

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Auteurs

Johan Kjeldbjerg Lassen (J)

Bioinformatics Research Center, Aarhus University, Universitetsbyen 81, 3. Building 1872, DK-8000 Aarhus, Denmark.

Robert Bradshaw (R)

Centre for Mass Spectrometry Imaging, Biomolecular Sciences Research Centre, Sheffield Hallam University, Sheffield S1 1WB, UK.

Palle Villesen (P)

Bioinformatics Research Center, Aarhus University, Universitetsbyen 81, 3. Building 1872, DK-8000 Aarhus, Denmark.
Department of Clinical Medicine, Aarhus University, Palle Juul-Jensens Boulevard 82, DK-8200 Aarhus, Denmark.

Simona Francese (S)

Centre for Mass Spectrometry Imaging, Biomolecular Sciences Research Centre, Sheffield Hallam University, Sheffield S1 1WB, UK.

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Classifications MeSH