A rare case of cutaneous myxoma with trichofolliculoma-like features.

Carney complex adnexal neoplasm cutaneous myxoma superficial angiomyxoma trichofolliculoma

Journal

Journal of cutaneous pathology
ISSN: 1600-0560
Titre abrégé: J Cutan Pathol
Pays: United States
ID NLM: 0425124

Informations de publication

Date de publication:
Oct 2023
Historique:
revised: 21 06 2023
received: 08 01 2023
accepted: 27 06 2023
medline: 11 9 2023
pubmed: 17 7 2023
entrez: 17 7 2023
Statut: ppublish

Résumé

Carney complex is a rare genetic disorder associated with a number of cutaneous lesions, especially cutaneous myxomas. We present a rare case of cutaneous myxoma (superficial angiomyxoma) with trichofolliculoma-like features in a patient with Carney complex, and explore how the associated histopathology provides critical context for elucidating the etiology of this benign neoplasm.

Identifiants

pubmed: 37455589
doi: 10.1111/cup.14496
doi:

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

861-863

Informations de copyright

© 2023 The Authors. Journal of Cutaneous Pathology published by John Wiley & Sons Ltd.

Références

Carney JA. Cutaneous myxomas. A major component of the complex of myxomas, spotty pigmentation, and endocrine overactivity. Arch Dermatol. 1986;122(7):790-798. doi:10.1001/archderm.122.7.790
Pérez Tato B, Sáez AC, Fernández PR. Superficial angiomyxoma with trichofolliculoma. Ann Diagn Pathol. 2008;12(5):375-377. doi:10.1016/j.anndiagpath.2007.02.005
Zou Y, Billings SD. Myxoid cutaneous tumors: a review. J Cutan Pathol. 2016;43(10):903-918. doi:10.1111/cup.12749
Kacerovska D, Requena L, Michal M, et al. Spectrum of cutaneous and soft tissue lesions in two Carney complex patients-adnexal induction versus authentic adnexal neoplasms. Am J Dermatopathol. 2012;34(7):729-736. doi:10.1097/dad.0b013e31824d1165
Sharma A, Khaitan N, Ko JS, et al. A clinicopathologic analysis of 54 cases of cutaneous myxoma. Hum Pathol. 2022;120:71-76. doi:10.1016/j.humpath.2021.12.003
Schulz T, Hartschuh W. The trichofolliculoma undergoes changes corresponding to the regressing normal hair follicle in its cycle. J Cutan Pathol. 1998;25(7):341-353. doi:10.1111/j.1600-0560.1998.tb01757.x
Ackerman AB, Viragh PA, Chongchitnant N. Fibrofolliculoma and trichodiscoma. Neoplasms with Follicular Differentiation (Ackerman's Histologic Diagnosis of Neoplastic Skin Diseases; A Method by Pattern Analysis). Lea & Febiger; 1993:245-279.
Courcoutsakis N, Prassopoulos P, Stratakis C. Carney complex: one more entity with skin and bone manifestations. Radiographics. 2015;35(1):296-297. doi:10.1148/rg.351140249
Veugelers M, Wilkes D, Burton K, et al. Comparative prkar1a genotype-phenotype analyses in humans with Carney complex and prkar1a haploinsufficient mice. Proc Natl Acad Sci U S A. 2004;101(39):14222-14227. doi:10.1073/pnas.0405535101
Headington JT. Tumors of the hair follicle. A review. Am J Pathol. 1976;85(2):479-514.

Auteurs

Kirsten M Johnson (KM)

Department of Dermatology, The Ohio State University, Columbus, Ohio, USA.

Jose A Plaza (JA)

Department of Dermatology, The Ohio State University, Columbus, Ohio, USA.
Department of Pathology, The Ohio State University, Columbus, Ohio, USA.

Jennifer A Sopkovich (JA)

Department of Dermatology, The Ohio State University, Columbus, Ohio, USA.

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