Evaluating Whether an Inpatient Initiative to Time Lab Draws in the Evening Reduces Anemia.


Journal

The journal of applied laboratory medicine
ISSN: 2576-9456
Titre abrégé: J Appl Lab Med
Pays: England
ID NLM: 101693884

Informations de publication

Date de publication:
07 09 2023
Historique:
received: 07 02 2023
accepted: 01 05 2023
medline: 8 9 2023
pubmed: 22 7 2023
entrez: 21 7 2023
Statut: ppublish

Résumé

Hospital acquired anemia is common during admission and can result in increased transfusion and length of stay. Recumbent posture is known to lead to lower hemoglobin measurements. We tested to see if an initiative promoting evening lab draws would lead to higher hemoglobin measurements due to more time in upright posture during the day and evening. We included patients hospitalized on 2 medical units, beginning March 26, 2020 and discharged prior to January 25, 2021. On one of the units, we implemented an initiative to have routine laboratory draws in the evening rather than the morning starting on August 26, 2020. There were 1217 patients on the control unit and 1265 on the intervention unit during the entire study period. First we used a linear mixed-effects model to see if timing of blood draw was associated with hemoglobin level in the pre-intervention period. We then compared levels of hemoglobin before and after the intervention using a difference-in-difference analysis. In the pre-intervention period, evening blood draws were associated with higher hemoglobin compared to morning (0.28; 95% CI, 0.22-0.35). Evening blood draws increased with the intervention (10.3% vs 47.9%, P > 0.001). However, the intervention floor was not associated with hemoglobin levels in difference-in-difference analysis (coefficient of -0.15; 95% CI, -0.51-0.21). While evening blood draws were associated with higher hemoglobin levels, an intervention that successfully changed timing of routine labs to the evening did not lead to an increase in hemoglobin levels.

Sections du résumé

BACKGROUND
Hospital acquired anemia is common during admission and can result in increased transfusion and length of stay. Recumbent posture is known to lead to lower hemoglobin measurements. We tested to see if an initiative promoting evening lab draws would lead to higher hemoglobin measurements due to more time in upright posture during the day and evening.
METHODS
We included patients hospitalized on 2 medical units, beginning March 26, 2020 and discharged prior to January 25, 2021. On one of the units, we implemented an initiative to have routine laboratory draws in the evening rather than the morning starting on August 26, 2020. There were 1217 patients on the control unit and 1265 on the intervention unit during the entire study period. First we used a linear mixed-effects model to see if timing of blood draw was associated with hemoglobin level in the pre-intervention period. We then compared levels of hemoglobin before and after the intervention using a difference-in-difference analysis.
RESULTS
In the pre-intervention period, evening blood draws were associated with higher hemoglobin compared to morning (0.28; 95% CI, 0.22-0.35). Evening blood draws increased with the intervention (10.3% vs 47.9%, P > 0.001). However, the intervention floor was not associated with hemoglobin levels in difference-in-difference analysis (coefficient of -0.15; 95% CI, -0.51-0.21).
CONCLUSIONS
While evening blood draws were associated with higher hemoglobin levels, an intervention that successfully changed timing of routine labs to the evening did not lead to an increase in hemoglobin levels.

Identifiants

pubmed: 37478815
pii: 7227856
doi: 10.1093/jalm/jfad041
doi:

Substances chimiques

Hemoglobins 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

887-895

Informations de copyright

© American Association for Clinical Chemistry 2023. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Auteurs

Jonah Zaretsky (J)

Department of Medicine, Division of Hospital Medicine, NYU Langone Health, New York, NY, United States.

Kevin P Eaton (KP)

Department of Medicine, Division of Hospital Medicine, NYU Langone Health, New York, NY, United States.

Christopher Sonne (C)

Department of Medicine, Division of Hospital Medicine, NYU Langone Health, New York, NY, United States.

Yunan Zhao (Y)

Department of Population Health, NYU Langone Health, New York, NY, United States.

Simon Jones (S)

Department of Population Health, NYU Langone Health, New York, NY, United States.

Katherine Hochman (K)

Department of Medicine, Division of Hospital Medicine, NYU Langone Health, New York, NY, United States.

Saul Blecker (S)

Department of Population Health, Department of Medicine, Division of Hospital Medicine, NYU Langone Health, New York, NY, United States.

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