Digital health and Clinical Patient Management System (CPMS) platform utility for data sharing of neuromuscular patients: the Italian EURO-NMD experience.


Journal

Orphanet journal of rare diseases
ISSN: 1750-1172
Titre abrégé: Orphanet J Rare Dis
Pays: England
ID NLM: 101266602

Informations de publication

Date de publication:
21 07 2023
Historique:
received: 15 09 2022
accepted: 18 06 2023
medline: 24 7 2023
pubmed: 22 7 2023
entrez: 21 7 2023
Statut: epublish

Résumé

The development of e-health technologies for teleconsultation and exchange of knowledge is one of the core purposes of European Reference Networks (ERNs), including the ERN EURO-NMD for rare neuromuscular diseases. Within ERNs, the Clinical Patient Management System (CPMS) is a web-based platform that seeks to boost active collaboration within and across the network, implementing data sharing. Through CPMS, it is possible to both discuss patient cases and to make patients' data available for registries and databases in a secure way. In this view, CPMS may be considered a sort of a temporary storage for patients' data and an effective tool for data sharing; it facilitates specialists' consultation since rare diseases (RDs) require multidisciplinary skills, specific, and outstanding clinical experience. Following European Union (EU) recommendation, and to promote the use of CPMS platform among EURO-NMD members, a twelve-month pilot project was set up to train the 15 Italian Health Care Providers (HCPs). In this paper, we report the structure, methods, and results of the teaching course, showing that tailored, ERN-oriented, training can significantly enhance the profitable use of the CPMS. Throughout the training course, 45 professionals learned how to use the many features of the CPMS, eventually opening 98 panels of discussion-amounting to 82% of the total panels included in the EURO-NMD. Since clinical, genetic, diagnostic, and therapeutic data of patients can be securely stored within the platform, we also highlight the importance of this platform as an effective tool to discuss and share clinical cases, in order to ease both case solving and data storing. In this paper, we discuss how similar course could help implementing the use of the platform, highlighting strengths and weaknesses of e-health for ERNs. The expected result is the creation of a "map" of neuromuscular patients across Europe that might be improved by a wider use of CPMS.

Sections du résumé

BACKGROUND
The development of e-health technologies for teleconsultation and exchange of knowledge is one of the core purposes of European Reference Networks (ERNs), including the ERN EURO-NMD for rare neuromuscular diseases. Within ERNs, the Clinical Patient Management System (CPMS) is a web-based platform that seeks to boost active collaboration within and across the network, implementing data sharing. Through CPMS, it is possible to both discuss patient cases and to make patients' data available for registries and databases in a secure way. In this view, CPMS may be considered a sort of a temporary storage for patients' data and an effective tool for data sharing; it facilitates specialists' consultation since rare diseases (RDs) require multidisciplinary skills, specific, and outstanding clinical experience. Following European Union (EU) recommendation, and to promote the use of CPMS platform among EURO-NMD members, a twelve-month pilot project was set up to train the 15 Italian Health Care Providers (HCPs). In this paper, we report the structure, methods, and results of the teaching course, showing that tailored, ERN-oriented, training can significantly enhance the profitable use of the CPMS.
RESULTS
Throughout the training course, 45 professionals learned how to use the many features of the CPMS, eventually opening 98 panels of discussion-amounting to 82% of the total panels included in the EURO-NMD. Since clinical, genetic, diagnostic, and therapeutic data of patients can be securely stored within the platform, we also highlight the importance of this platform as an effective tool to discuss and share clinical cases, in order to ease both case solving and data storing.
CONCLUSIONS
In this paper, we discuss how similar course could help implementing the use of the platform, highlighting strengths and weaknesses of e-health for ERNs. The expected result is the creation of a "map" of neuromuscular patients across Europe that might be improved by a wider use of CPMS.

Identifiants

pubmed: 37480080
doi: 10.1186/s13023-023-02776-5
pii: 10.1186/s13023-023-02776-5
pmc: PMC10360326
doi:

Substances chimiques

4-chlorophenyl methyl sulfide 123-09-1

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

196

Informations de copyright

© 2023. The Author(s).

Références

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pubmed: 35856030
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pubmed: 32738884
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pubmed: 28198707
Orphanet J Rare Dis. 2017 Aug 7;12(1):137
pubmed: 28784158
Telemed J E Health. 2019 Jul;25(7):541-550
pubmed: 30136898

Auteurs

Fernanda Fortunato (F)

Medical Genetics Unit, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
Medical Genetics Unit, Department of Mother and Child, Sant'Anna University Hospital of Ferrara, Ferrara, Italy.

Francesca Bianchi (F)

Department of Clinical and Experimental Medicine, Neurological Clinic, University of Pisa, Pisa, Italy.

Giulia Ricci (G)

Department of Clinical and Experimental Medicine, Neurological Clinic, University of Pisa, Pisa, Italy.

Francesca Torri (F)

Department of Clinical and Experimental Medicine, Neurological Clinic, University of Pisa, Pisa, Italy.

Francesca Gualandi (F)

Medical Genetics Unit, Department of Mother and Child, Sant'Anna University Hospital of Ferrara, Ferrara, Italy.

Marcella Neri (M)

Medical Genetics Unit, Department of Mother and Child, Sant'Anna University Hospital of Ferrara, Ferrara, Italy.

Marianna Farnè (M)

Medical Genetics Unit, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
Medical Genetics Unit, Department of Mother and Child, Sant'Anna University Hospital of Ferrara, Ferrara, Italy.

Fabio Giannini (F)

Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy.

Alessandro Malandrini (A)

Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy.

Nila Volpi (N)

Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy.

Diego Lopergolo (D)

Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy.

Vincenzo Silani (V)

Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.
Department of Pathophysiology and Transplantation, "Dino Ferrari" Center, Università Degli Studi Di Milano, Milan, Italy.

Nicola Ticozzi (N)

Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.
Department of Pathophysiology and Transplantation, "Dino Ferrari" Center, Università Degli Studi Di Milano, Milan, Italy.

Federico Verde (F)

Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.
Department of Pathophysiology and Transplantation, "Dino Ferrari" Center, Università Degli Studi Di Milano, Milan, Italy.

Davide Pareyson (D)

Unit of Rare Neurodegenerative and Neurometabolic Diseases, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.

Silvia Fenu (S)

Unit of Rare Neurodegenerative and Neurometabolic Diseases, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.

Silvia Bonanno (S)

Neuroimmunology and Neuromuscular Diseases Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.

Vincenzo Nigro (V)

Department of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Naples, Italy.

Cristina Peduto (C)

Department of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.

Paola D'Ambrosio (P)

Department of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.

Roberta Zeuli (R)

Department of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.

Mariateresa Zanobio (M)

Department of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.

Esther Picillo (E)

Department of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.

Serenella Servidei (S)

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.

Guido Primiano (G)

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.

Cristina Sancricca (C)

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.

Monica Sciacco (M)

Neuromuscular and Rare Disease Unit, Department of Neuroscience, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Roberta Brusa (R)

Neuromuscular and Rare Disease Unit, Department of Neuroscience, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Massimiliano Filosto (M)

Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
ASST Spedali Civili Di Brescia, Brescia, Italy.
NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy.

Stefano Cotti Piccinelli (S)

Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
ASST Spedali Civili Di Brescia, Brescia, Italy.
NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy.

Elena Pegoraro (E)

Department of Neuroscience, University of Padova, Padua, Italy.

Tiziana Mongini (T)

Department of Neurosciences "Rita Levi Montalcini", University of Turin, Turin, Italy.

Luca Solero (L)

Department of Neurosciences "Rita Levi Montalcini", University of Turin, Turin, Italy.

Giulio Gadaleta (G)

Department of Neurosciences "Rita Levi Montalcini", University of Turin, Turin, Italy.

Chiara Brusa (C)

Department of Neurosciences "Rita Levi Montalcini", University of Turin, Turin, Italy.

Carlo Minetti (C)

Pediatric Neurology Unit and Muscle Unit, IRCCS Istituto Giannina Gaslini, Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy.

Claudio Bruno (C)

Center of Translational and Experimental Myology, IRCCS Istituto Giannina Gaslini, Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy.

Chiara Panicucci (C)

Center of Translational and Experimental Myology, IRCCS Istituto Giannina Gaslini, Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy.

Valeria A Sansone (VA)

The NEMO (NEuroMuscular Omniservice) Clinical Center, Milan, Italy.
Neurorehabilitation Unit, University of Milan, Milan, Italy.

Christian Lunetta (C)

The NEMO (NEuroMuscular Omniservice) Clinical Center, Milan, Italy.

Alice Zanolini (A)

The NEMO (NEuroMuscular Omniservice) Clinical Center, Milan, Italy.

Antonio Toscano (A)

Neurology and Neuromuscular Diseases Unit, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
ERN-NMD Center of Messina, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.

Alessia Pugliese (A)

Neurology and Neuromuscular Diseases Unit, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.

Giulia Nicocia (G)

Neurology and Neuromuscular Diseases Unit, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.

Enrico Bertini (E)

Unit of Neuromuscular and Neurodegenerative Disorders, Department of Neurosciences, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.

Michela Catteruccia (M)

Unit of Neuromuscular and Neurodegenerative Disorders, Department of Neurosciences, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.

Daria Diodato (D)

Unit of Neuromuscular and Neurodegenerative Disorders, Department of Neurosciences, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.

Antonio Atalaia (A)

Service of Neuromyology, APHP-GH Pitié-Salpêtrière, Sorbonne Université, Paris, France.

Teresinha Evangelista (T)

Neuromuscular Morphology Unit, Institute of Myology, GHU Pitié-Salpêtrière, Sorbonne Université, Paris, France.

Gabriele Siciliano (G)

Department of Clinical and Experimental Medicine, Neurological Clinic, University of Pisa, Pisa, Italy.

Alessandra Ferlini (A)

Medical Genetics Unit, Department of Medical Sciences, University of Ferrara, Ferrara, Italy. fla@unife.it.
Medical Genetics Unit, Department of Mother and Child, Sant'Anna University Hospital of Ferrara, Ferrara, Italy. fla@unife.it.

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