Ten years of Italian mini-invasiveness: the I Go MILS registry as a tool of dissemination, characterization and networking.


Journal

Updates in surgery
ISSN: 2038-3312
Titre abrégé: Updates Surg
Pays: Italy
ID NLM: 101539818

Informations de publication

Date de publication:
Sep 2023
Historique:
received: 11 07 2023
accepted: 15 07 2023
medline: 18 8 2023
pubmed: 25 7 2023
entrez: 24 7 2023
Statut: ppublish

Résumé

Purposes of this study are to evaluate the main changes that have occurred in the Italian MILS activity in the last decade in terms of indications, approaches and outcomes as reported in the national registry and to provide specific details on the main areas of development of MILS. Data from patients undergoing minimally invasive liver resections at centers included in the I Go MILS Registry from its start-up (November 2014) to March 2023 were analyzed for the purposes of this study. The registry is intention-to-treat and prospective. Global recruitment trends stratified by indication to surgery and type of approach were analysed. 7413 MILS procedures were performed across all centers (median number of procedures per center: 63). Years (2020-2023) displayed a significantly higher proportion of treated patients diagnosed with hepatocellular carcinoma (HCC) (38.2% vs. 28.9% and 33.9%, p < 0.001) and cholangiocarcinoma (6.7% vs. 6.5% and 4.2%, p < 0.001) compared to the preceding triennial periods. Additionally, technical complexity demonstrated an increased prominence in Years (2019-2023) with a significantly higher percentage of grade III cases compared to the earlier periods (39.3% vs. 21.7% and 25.6%, p < 0.001). Annual case trends focusing on laparoscopic and robotic techniques demonstrated a steadily increase in the use of these techniques for complex case mix of indications. Overall, attitude and attention to MILS approach has evolved, so that currently indications to hepatic mini-invasiveness have expanded and surgical technique has been refined: Areas mainly involved in increasing growth trends are hepatocellular carcinoma, possible applications of MILS in transplant setting, intrahepatic cholangiocarcinoma and robotic approach.

Identifiants

pubmed: 37488408
doi: 10.1007/s13304-023-01597-2
pii: 10.1007/s13304-023-01597-2
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1457-1469

Investigateurs

Rebecca Marino (R)
Nadia Russolillo (N)
Andrea Ruzzenente (A)
Enrico Gringeri (E)
Francesco Ardito (F)
Carlo Sposito (C)
Riccardo De Carlis (R)
Marco Colasanti (M)
Pasquale Bonsignore (P)
Stefano Di Sandro (S)
Giuliano La Barba (G)
Mario Giuffrida (M)
Matteo Cescon (M)
Matteo Barabino (M)
Ugo Boggi (U)
Mohammed Abu Hilal (MA)
Giovanni Vennarecci (G)
Giorgio Rossi (G)
Gian Luca Grazi (GL)
Antonio Frena (A)
Leonardo Vincenti (L)
Alberto Brolese (A)
Fulvio Calise (F)
Luca Morelli (L)
Fausto Zamboni (F)
Raffaele Romito (R)
Guido Torzilli (G)
Stefano Berti (S)
Guido Griseri (G)
Marco Filauro (M)
Marco Massani (M)
Giacomo Batignani (G)
Riccardo Memeo (R)
Giuseppe Navarra (G)
Giuseppe Tisone (G)
Andrea Coratti (A)
Graziano Ceccarelli (G)
Marco Vivarelli (M)
Giulio Belli (G)
Christian Cotsoglou (C)
Pietro Mezzatesta (P)
Adelmo Antonucci (A)
Luigi Veneroni (L)
Michele Colledan (M)
Amilcare Parisi (A)
Silvio Guerriero (S)
Marco Spada (M)
Antonio Floridi (A)
Giovanni Sgroi (G)
Paola Tarchi (P)
Dario Lorenzin (D)
Alberto Patriti (A)
Dario Ribero (D)
Pietro Maida (P)
Luigi Boni (L)
Andrea Percivale (A)
Umberto Montin (U)
Stefano Mancini (S)
Marcello Spampinato (M)

Informations de copyright

© 2023. Italian Society of Surgery (SIC).

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Auteurs

Francesca Ratti (F)

Hepatobiliary Surgery Division, IRCCS San Raffaele Hospital, Via Olgettina 60, 20132, Milan, Italy. ratti.francesca@hsr.it.
Vita-Salute San Raffaele University, Milan, Italy. ratti.francesca@hsr.it.

Alessandro Ferrero (A)

Department of General and Oncological Surgery, Mauriziano Hospital Umberto I, Turin, Italy.

Alfredo Guglielmi (A)

Department of Surgery, Division of General and Hepatobiliary Surgery, School of Medicine, University of Verona, Verona, Italy.

Umberto Cillo (U)

General Surgery 2-Hepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, University of Padua, Padua, Italy.

Felice Giuliante (F)

Hepatobiliary Surgery Unit, Fondazione "Policlinico Universitario A. Gemelli" IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.

Vincenzo Mazzaferro (V)

Hepato-Pancreatic-Biliary Surgery and Liver Transplantation, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.

Luciano De Carlis (L)

Department of General Surgery and Transplantation, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
School of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy.

Giuseppe Maria Ettorre (GM)

Department of General and Hepatobiliary and Pancreatic Surgery, Liver Transplantation Service, San Camillo-Forlanini Hospital, Rome, Italy.

Salvatore Gruttadauria (S)

Department for the Treatment and Study of Abdominal Diseases and Abdominal Transplantation, Istituto di Ricovero e Cura a Carattere Scientifico-Istituto Mediterraneo per i Trapianti e Terapie ad alta specializzazione (IRCCS-ISMETT), University of Pittsburgh Medical Center (UPMC), Palermo, Italy.

Fabrizio Di Benedetto (F)

Hepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, University of Modena and Reggio Emilia, Modena, Italy.

Giorgio Ercolani (G)

Department of Medical and Surgical Sciences-DIMEC, Alma Mater Studiorum - University of Bologna, Bologna, Italy.
Department of General and Oncologic Surgery, Morgagni-Pierantoni Hospital, Ausl Romagna, Forlì, Italy.

Raffaele Dalla Valle (RD)

Department of Medicine and Surgery, University of Parma, Parma, Italy.

Andrea Belli (A)

Department of Abdominal Oncology, Division of Hepatopancreatobiliary Surgical Oncology, National Cancer Center-IRCCS-G. Pascale, Naples, Italy.

Elio Jovine (E)

Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.
Department of General Surgery, IRCCS, Azienda Ospedaliero-Universitaria di Bologna, Maggiore Hospital, Bologna, Italy.

Matteo Ravaioli (M)

Hepatobiliary and Transplant Unit, Policlinico Sant'Orsola IRCCS, University of Bologna, Bologna, Italy.

Luca Aldrighetti (L)

Hepatobiliary Surgery Division, IRCCS San Raffaele Hospital, Via Olgettina 60, 20132, Milan, Italy.
Vita-Salute San Raffaele University, Milan, Italy.

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