Displacement of human milk during fortification: An experimental study.
critical care
enteral nutrition
life cycle
neonates
nutrition
research and diseases
Journal
JPEN. Journal of parenteral and enteral nutrition
ISSN: 1941-2444
Titre abrégé: JPEN J Parenter Enteral Nutr
Pays: United States
ID NLM: 7804134
Informations de publication
Date de publication:
Nov 2023
Nov 2023
Historique:
revised:
18
07
2023
received:
27
01
2023
accepted:
24
07
2023
medline:
7
11
2023
pubmed:
25
7
2023
entrez:
25
7
2023
Statut:
ppublish
Résumé
This study quantified the displacement of human milk by commercial human milk fortifiers (HMFs) and infant formulas. Commercial liquid HMFs and powder infant formulas were added to pasteurized pooled donor human milk in triplicate, stirred, and weighed. The difference in weight between unfortified and fortified human milk at 22, 24, 26, 27, 28, and 30 kcal/ounce was calculated. The displacement of human milk by liquid HMFs and powder infant formulas and powder HMF was highly associated with energy density. A human milk-derived HMF displaced significantly more human milk when compared with bovine milk-derived HMFs at equivalent energy densities. Similarly, powder infant formulas displaced less human milk when compared with a powder HMF, and the addition of hydrolyzed powder infant formulas resulted in less human milk displacement when compared with nonhydrolyzed powder infant formulas. The displacement of human milk by commercial liquid HMFs and infant formulas must be considered when selecting a fortifying strategy.
Sections du résumé
BACKGROUND
BACKGROUND
This study quantified the displacement of human milk by commercial human milk fortifiers (HMFs) and infant formulas.
METHODS
METHODS
Commercial liquid HMFs and powder infant formulas were added to pasteurized pooled donor human milk in triplicate, stirred, and weighed. The difference in weight between unfortified and fortified human milk at 22, 24, 26, 27, 28, and 30 kcal/ounce was calculated.
RESULTS
RESULTS
The displacement of human milk by liquid HMFs and powder infant formulas and powder HMF was highly associated with energy density. A human milk-derived HMF displaced significantly more human milk when compared with bovine milk-derived HMFs at equivalent energy densities. Similarly, powder infant formulas displaced less human milk when compared with a powder HMF, and the addition of hydrolyzed powder infant formulas resulted in less human milk displacement when compared with nonhydrolyzed powder infant formulas.
CONCLUSIONS
CONCLUSIONS
The displacement of human milk by commercial liquid HMFs and infant formulas must be considered when selecting a fortifying strategy.
Substances chimiques
Powders
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1062-1066Subventions
Organisme : This research was supported by an unrestricted grant from Mead Johnson.
Informations de copyright
© 2023 American Society for Parenteral and Enteral Nutrition.
Références
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