Preparation and characterization of poly(3-hydroxybutyrate)/chitosan composite films using acetic acid as a solvent.


Journal

International journal of biological macromolecules
ISSN: 1879-0003
Titre abrégé: Int J Biol Macromol
Pays: Netherlands
ID NLM: 7909578

Informations de publication

Date de publication:
01 Sep 2023
Historique:
received: 19 05 2023
revised: 27 06 2023
accepted: 22 07 2023
medline: 22 9 2023
pubmed: 27 7 2023
entrez: 26 7 2023
Statut: ppublish

Résumé

Poly(3-hydroxybutyrate) and chitosan are among the most widely used polymers for biomedical applications due to their biocompatibility, renewability and low toxicity. The creation of composite materials based on biopolymers belonging to different classes makes it possible to overcome the disadvantages of each of the components and to obtain a material with specific properties. Solving this problem is associated with difficulties in the selection of conditions and solvents for obtaining the composite material. In our study, acetic acid was used as a common solvent for hydrophobic poly(3-hydroxybutyrate) and chitosan. Mechanical, thermal, physicochemical and surface properties of the composites and homopolymers were investigated. The composite films had less crystallinity and hydrophobicity than poly(3-hydroxybutyrate), and the addition of chitosan caused an increase in moisture absorption, a decrease in contact angle and changes in mechanical properties of the poly(3-hydroxybutyrate). The inclusion of varying amounts of chitosan controlled the properties of the composite, which will be important in the future for its specific biomedical applications.

Identifiants

pubmed: 37494998
pii: S0141-8130(23)02865-9
doi: 10.1016/j.ijbiomac.2023.125970
pii:
doi:

Substances chimiques

Chitosan 9012-76-4
3-Hydroxybutyric Acid TZP1275679
Acetic Acid Q40Q9N063P
Solvents 0
poly-beta-hydroxybutyrate 26063-00-3

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

125970

Informations de copyright

Copyright © 2023 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Yulia V. Zhuikova reports financial support was provided by Russian Science Foundation.

Auteurs

Yulia V Zhuikova (YV)

Research Center of Biotechnology of the Russian Academy of Sciences, Moscow, Russia. Electronic address: zhuikova.uv@gmail.com.

Vsevolod A Zhuikov (VA)

Research Center of Biotechnology of the Russian Academy of Sciences, Moscow, Russia.

Tatiana K Makhina (TK)

Research Center of Biotechnology of the Russian Academy of Sciences, Moscow, Russia.

Yuri M Efremov (YM)

Institute for Regenerative Medicine, Sechenov University, Moscow, Russia.

Nadezhda A Aksenova (NA)

Institute for Regenerative Medicine, Sechenov University, Moscow, Russia; N.N. Semenov Federal Research Center for Chemical Physics, Russian Academy of Sciences, Moscow, Russia.

Peter S Timashev (PS)

Institute for Regenerative Medicine, Sechenov University, Moscow, Russia; World-Class Research Center "Digital Biodesign and Personalized Healthcare" Moscow, Russia; Chemistry Department, Lomonosov Moscow State University, Moscow, Russia.

Garina A Bonartseva (GA)

Research Center of Biotechnology of the Russian Academy of Sciences, Moscow, Russia.

Valery P Varlamov (VP)

Research Center of Biotechnology of the Russian Academy of Sciences, Moscow, Russia.

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Classifications MeSH